The Classification and Prediction of Ferroptosis-Related Genes in ALS: A Pilot Study

The Gpx4NIKO Mouse Is a Versatile Model for Testing Interventions Targeting Ferroptotic Cell Death of Spinal Motor Neurons

(2022) Robert Cole Evans et al.   NEUROTOXICITY RESEARCH

Autophagy and ALS: mechanistic insights and therapeutic implications

(2021) Jason P. Chua et al.   Autophagy

Delineating the molecular and phenotypic spectrum of the SETD1B-related syndrome

(2021) Marjolein J. A. Weerts et al.   GENETICS IN MEDICINE

The landscape of gene co-expression modules correlating with prognostic genetic abnormalities in AML

(2021) Chao Guo et al.   Journal of Translational Medicine

Overexpression of ferroptosis defense enzyme Gpx4 retards motor neuron disease of SOD1G93A mice

(2021) Liuji Chen et al.   Scientific Reports

Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis

(2021) Taide Wang et al.   CELL DEATH AND DIFFERENTIATION

Identification of key genes controlling breast cancer stem cell characteristics via stemness indices analysis

(2020) Jianying Pei et al.   Journal of Translational Medicine

Biomaterials in Neurodegenerative Disorders: A Promising Therapeutic Approach

(2020) Matteo Bordoni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Abnormal Serum Iron-Status Indicator Changes in Amyotrophic Lateral Sclerosis (ALS) Patients: A Meta-Analysis

(2020) Lan Wang et al.   Frontiers in Neurology

Elevated serum ferritin level as a predictor of reduced survival in patients with sporadic amyotrophic lateral sclerosis in China: a retrospective study

(2019) Qionghua Sun et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Iron Metabolism of the Skeletal Muscle and Neurodegeneration

(2019) Malgorzata Halon-Golabek et al.   Frontiers in Neuroscience

Depression and risk of cognitive dysfunctions in amyotrophic lateral sclerosis

(2019) Fabiola De Marchi et al.   ACTA NEUROLOGICA SCANDINAVICA

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke

(2019) Ishraq Alim et al.   CELL

Imaging Hypoxic Stress and the Treatment of Amyotrophic Lateral Sclerosis with Dimethyloxalylglycine in a Mice Model

(2019) Emi Nomura et al.   NEUROSCIENCE

Edaravone, a free radical scavenger, protects against ferroptotic cell death in vitro

(2019) Takujiro Homma et al.   EXPERIMENTAL CELL RESEARCH

Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes

(2019) Tae-Jun Park et al.   Cell Death & Disease

Global variation in prevalence and incidence of amyotrophic lateral sclerosis: a systematic review and meta-analysis

(2019) Lu Xu et al.   JOURNAL OF NEUROLOGY

Could Conservative Iron Chelation Lead to Neuroprotection in Amyotrophic Lateral Sclerosis?

(2018) Caroline Moreau et al.   ANTIOXIDANTS & REDOX SIGNALING

Revisiting LAMP1 as a marker for degradative autophagy-lysosomal organelles in the nervous system

(2018) Xiu-Tang Cheng et al.   Autophagy

Astroglial and microglial contributions to iron metabolism disturbance in Parkinson's disease

(2018) Ning Song et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Autophagy and mitophagy in ALS

(2018) Chantell S. Evans et al.   NEUROBIOLOGY OF DISEASE

Whole blood transcriptome analysis in amyotrophic lateral sclerosis: A biomarker study

(2018) Wouter van Rheenen et al.   PLoS One

Striking while the iron is hot: Iron metabolism and Ferroptosis in neurodegeneration

(2018) Shashank Masaldan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent

(2018) Koki Fujimori et al.   NATURE MEDICINE

NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence?

(2017) Silvia Sorce et al.   FREE RADICAL BIOLOGY AND MEDICINE

ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation

(2017) Reddy Ranjith K. Sama et al.   Scientific Reports

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

Identification of ACSL4 as a biomarker and contributor of ferroptosis

(2016) Hua Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy

(2016) Christopher P Webster et al.   EMBO JOURNAL

Ferroptosis, a new form of cell death, and its relationships with tumourous diseases

(2016) Haitao Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC

(2016) Bruce Do Van et al.   NEUROBIOLOGY OF DISEASE

Sporadic and hereditary amyotrophic lateral sclerosis (ALS)

(2015) Senda Ajroud-Driss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis

(2015) Liuji Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells

(2015) Shu-Feng Zhou et al.   Drug Design Development and Therapy

LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease

(2015) Michelle Rothaug et al.   Acta Neuropathologica Communications

Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice

(2014) Oleg Butovsky et al.   ANNALS OF NEUROLOGY

NADPH oxidase (NOX2) activity is a modifier of survival in ALS

(2014) Giuseppe Marrali et al.   JOURNAL OF NEUROLOGY

The Neurology of mTOR

(2014) Jonathan O. Lipton et al.   NEURON

Absence of lipofuscin in motor neurons of SOD1-linked ALS mice

(2014) U. Bandyopadhyay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advances in kinase targeting: current clinical use and clinical trials

(2014) Mathias Rask-Andersen et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition

(2014) Michael V. Gormally et al.   Nature Communications

Amyotrophic Lateral Sclerosis Outcome Measures and the Role of Albumin and Creatinine

(2014) Adriano Chiò et al.   JAMA Neurology

Iron deposits in the chronically inflamed central nervous system and contributes to neurodegeneration

(2013) Hjalte Holm Andersen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Brain iron MRI: A biomarker for amyotrophic lateral sclerosis

(2013) Aleksandar Ignjatović et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Neuroprotection through Excitability and mTOR Required in ALS Motoneurons to Delay Disease and Extend Survival

(2013) Smita Saxena et al.   NEURON

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Elevated Serum Ferritin Is Associated with Reduced Survival in Amyotrophic Lateral Sclerosis

(2012) Yann Nadjar et al.   PLoS One

pROC: an open-source package for R and S+ to analyze and compare ROC curves

(2011) Xavier Robin et al.   BMC BIOINFORMATICS

Prevention of Motor Neuron Degeneration by Novel Iron Chelators in SOD1G93A Transgenic Mice of Amyotrophic Lateral Sclerosis

(2011) Qian Wang et al.   Neurodegenerative Diseases

The antioxidant edaravone attenuates ER-stress-mediated cardiac apoptosis and dysfunction in rats with autoimmune myocarditis

(2010) Hiroko Shimazaki et al.   FREE RADICAL RESEARCH

Deregulation of the hypoxia inducible factor-1α pathway in monocytes from sporadic amyotrophic lateral sclerosis patients

(2010) C. Moreau et al.   NEUROSCIENCE

Prognostic factors in ALS: A critical review

(2009) Adriano Chiò et al.   Amyotrophic Lateral Sclerosis

Dysregulation of Iron Homeostasis in the CNS Contributes to Disease Progression in a Mouse Model of Amyotrophic Lateral Sclerosis

(2009) S. Y. Jeong et al.   JOURNAL OF NEUROSCIENCE

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS