Iron deposits in the chronically inflamed central nervous system and contributes to neurodegeneration
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Title
Iron deposits in the chronically inflamed central nervous system and contributes to neurodegeneration
Authors
Keywords
Blood–brain barrier, Cell death, Iron accumulation, Macrophage, Neurodegeneration, Nitric oxide, Phagocytosis
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 71, Issue 9, Pages 1607-1622
Publisher
Springer Nature
Online
2013-11-11
DOI
10.1007/s00018-013-1509-8
References
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Note: Only part of the references are listed.- Iron uptake in quiescent and inflammation-activated astrocytes: A potentially neuroprotective control of iron burden
- (2013) Ilaria Pelizzoni et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Neuron-Microglia Interaction in Neuroinflammation
- (2013) Akio Suzumura CURRENT PROTEIN & PEPTIDE SCIENCE
- Cessation of Neoangiogenesis in Alzheimer's Disease Follows Amyloid-beta Immunization
- (2013) Kaan E. Biron et al. Scientific Reports
- Iron levels in polarized macrophages: Regulation of immunity and autoimmunity
- (2012) Stefania Recalcati et al. AUTOIMMUNITY REVIEWS
- Pantothenate Kinase-Associated Neurodegeneration
- (2012) Monika B. Hartig et al. CURRENT DRUG TARGETS
- Chelating Agents for Neurodegenerative Diseases
- (2012) R. J. Ward et al. CURRENT MEDICINAL CHEMISTRY
- Amyotrophic lateral sclerosis
- (2012) Albert C. Ludolph et al. CURRENT OPINION IN NEUROLOGY
- Huntingtonʼs disease
- (2012) Ainhi D. Ha et al. CURRENT OPINION IN NEUROLOGY
- Reactive Oxygen Species and Inhibitors of Inflammatory Enzymes, NADPH Oxidase, and iNOS in Experimental Models of Parkinson’s Disease
- (2012) Sushruta Koppula et al. MEDIATORS OF INFLAMMATION
- The relationship of copper to DNA damage and damage prevention in humans
- (2012) Maria C. Linder MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- The catalytic center of ferritin regulates iron storage via Fe(II)-Fe(III) displacement
- (2012) Kourosh Honarmand Ebrahimi et al. Nature Chemical Biology
- Elevated Oxidative Stress and Decreased Antioxidant Function in the Human Hippocampus and Frontal Cortex with Increasing Age: Implications for Neurodegeneration in Alzheimer’s Disease
- (2012) C. Venkateshappa et al. NEUROCHEMICAL RESEARCH
- Elevated brain iron is independent from atrophy in Huntington's Disease
- (2012) Eve M. Dumas et al. NEUROIMAGE
- Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system
- (2012) Mª Carmen Hernández-Romero et al. NEUROTOXICOLOGY
- Brain rust: Recent discoveries on the role of oxidative stress in neurodegenerative diseases
- (2012) Diêgo Madureira de Oliveira et al. NUTRITIONAL NEUROSCIENCE
- Mechanism of Oxidative Stress in Neurodegeneration
- (2012) Sonia Gandhi et al. Oxidative Medicine and Cellular Longevity
- Iron Accumulation in Deep Cortical Layers Accounts for MRI Signal Abnormalities in ALS: Correlating 7 Tesla MRI and Pathology
- (2012) Justin Y. Kwan et al. PLoS One
- Copper Imbalances in Ruminants and Humans: Unexpected Common Ground
- (2012) Neville F. Suttle Advances in Nutrition
- Advances in the Pathogenesis of Alzheimer’s Disease: Focusing on Tau-Mediated Neurodegeneration
- (2012) Yale Duan et al. Translational Neurodegeneration
- Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer's Disease
- (2011) Alberto Serrano-Pozo et al. AMERICAN JOURNAL OF PATHOLOGY
- Heterogenous distribution of ferroportin-containing neurons in mouse brain
- (2011) Michael W. Boserup et al. BIOMETALS
- Genetics of Neurodegeneration with Brain Iron Accumulation
- (2011) Allison Gregory et al. Current Neurology and Neuroscience Reports
- Iron mediates endothelial cell damage and blood-brain barrier opening in the hippocampus after transient forebrain ischemia in rats
- (2011) Sun Mi Won et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Inhibition of Microglial Phagocytosis Is Sufficient To Prevent Inflammatory Neuronal Death
- (2011) J. J. Neher et al. JOURNAL OF IMMUNOLOGY
- Mechanisms of neurodegeneration shared between multiple sclerosis and Alzheimer’s disease
- (2011) Hans Lassmann JOURNAL OF NEURAL TRANSMISSION
- Inflammation in the early stages of neurodegenerative pathology
- (2011) Preeti J. Khandelwal et al. JOURNAL OF NEUROIMMUNOLOGY
- Iron and Iron Regulatory Proteins in Amoeboid Microglial Cells Are Linked to Oligodendrocyte Death in Hypoxic Neonatal Rat Periventricular White Matter through Production of Proinflammatory Cytokines and Reactive Oxygen/Nitrogen Species
- (2011) G. Rathnasamy et al. JOURNAL OF NEUROSCIENCE
- The potential application of iron chelators for the treatment of neurodegenerative diseases
- (2011) Robert C. Hider et al. Metallomics
- Iron-related MRI images in patients with pantothenate kinase-associated neurodegeneration (PKAN) treated with deferiprone: Results of a phase II pilot trial
- (2011) Giovanna Zorzi et al. MOVEMENT DISORDERS
- Cerebrovascular disorders: molecular insights and therapeutic opportunities
- (2011) Erik Storkebaum et al. NATURE NEUROSCIENCE
- Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
- (2011) Marco Prinz et al. NATURE NEUROSCIENCE
- Upcoming treatments in Parkinson's disease, including gene therapy
- (2011) Robert L Rodnitzky PARKINSONISM & RELATED DISORDERS
- Amyloid Triggers Extensive Cerebral Angiogenesis Causing Blood Brain Barrier Permeability and Hypervascularity in Alzheimer's Disease
- (2011) Kaan E. Biron et al. PLoS One
- Blood-derived iron mediates free radical production and neuronal death in the hippocampal CA1 area following transient forebrain ischemia in rat
- (2010) Ui Jin Park et al. ACTA NEUROPATHOLOGICA
- The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice
- (2010) Wei-Jian Zhang et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Mutant Ferritin L-chains That Cause Neurodegeneration Act in a Dominant-negative Manner to Reduce Ferritin Iron Incorporation
- (2010) Sara Luscieti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice
- (2010) Ivana De Domenico et al. JOURNAL OF CLINICAL INVESTIGATION
- Brain iron metabolism and its perturbation in neurological diseases
- (2010) Robert R. Crichton et al. JOURNAL OF NEURAL TRANSMISSION
- Clinically available iron chelators induce neuroprotection in the 6-OHDA model of Parkinson’s disease after peripheral administration
- (2010) David T. Dexter et al. JOURNAL OF NEURAL TRANSMISSION
- Ulcerative colitis exacerbates lipopolysaccharide-induced damage to the nigral dopaminergic system: potential risk factor in Parkinson`s disease
- (2010) Ruth F. Villarán et al. JOURNAL OF NEUROCHEMISTRY
- Inflammatory Neurodegeneration and Mechanisms of Microglial Killing of Neurons
- (2010) Guy C. Brown et al. MOLECULAR NEUROBIOLOGY
- Systemic inflammatory cells fight off neurodegenerative disease
- (2010) Michal Schwartz et al. Nature Reviews Neurology
- Macrophage Apoptosis in Advanced Atherosclerosis
- (2009) Ira Tabas et al. Annals of the New York Academy of Sciences
- Role of hepcidin in murine brain iron metabolism
- (2009) S.-M. Wang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Differential regulation of iron homeostasis during human macrophage polarized activation
- (2009) Stefania Recalcati et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Iron elevations in the aging Parkinsonian brain: a consequence of impaired iron homeostasis?
- (2009) Donna W. Lee et al. JOURNAL OF NEUROCHEMISTRY
- Structure and function of the blood–brain barrier
- (2009) N. Joan Abbott et al. NEUROBIOLOGY OF DISEASE
- Alternative Activation of Macrophages: An Immunologic Functional Perspective
- (2008) Fernando O. Martinez et al. Annual Review of Immunology
- Intracellular labile iron promotes firm adhesion of human monocytes to endothelium under flow and transendothelial migration
- (2008) Apriliana E.R. Kartikasari et al. ATHEROSCLEROSIS
- Atherosclerosis—An immune disease
- (2008) Göran K. Hansson ATHEROSCLEROSIS
- Basolateral Aggregated Rat Amyloidβ(1-42) Potentiates Transmigration of Primary Rat Monocytes through a Rat Blood-Brain Barrier
- (2008) Christian Humpel CURRENT NEUROVASCULAR RESEARCH
- Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity
- (2008) Kryslaine O. Lopes et al. GLIA
- A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain
- (2008) Jae K. Ryu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Expression of a Mutant Form of the Ferritin Light Chain Gene Induces Neurodegeneration and Iron Overload in Transgenic Mice
- (2008) R. Vidal et al. JOURNAL OF NEUROSCIENCE
- Inflammatory Response in the Hippocampus of PS1M146L/APP751SL Mouse Model of Alzheimer's Disease: Age-Dependent Switch in the Microglial Phenotype from Alternative to Classic
- (2008) S. Jimenez et al. JOURNAL OF NEUROSCIENCE
- Oxidative and Inflammatory Pathways in Parkinson’s Disease
- (2008) Rebecca L. Miller et al. NEUROCHEMICAL RESEARCH
- Blood-brain barrier disruption in the striatum of rats treated with 3-nitropropionic acid
- (2008) Joaquim Duran-Vilaregut et al. NEUROTOXICOLOGY
- Mechanisms of microglia accumulation in Alzheimer’s disease: therapeutic implications
- (2008) Joseph El Khoury et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Flow cytometry measurement of the labile iron pool in human hematopoietic cells
- (2007) Eugenia Prus et al. CYTOMETRY PART A
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