Overexpression of ferroptosis defense enzyme Gpx4 retards motor neuron disease of SOD1G93A mice
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Title
Overexpression of ferroptosis defense enzyme Gpx4 retards motor neuron disease of SOD1G93A mice
Authors
Keywords
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Journal
Scientific Reports
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-06-18
DOI
10.1038/s41598-021-92369-8
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Related references
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- (2020) Snežana Spasić et al. CURRENT DRUG TARGETS
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- Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration
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- (2014) Jose Pedro Friedmann Angeli et al. NATURE CELL BIOLOGY
- Therapeutic AAV9-mediated Suppression of Mutant SOD1 Slows Disease Progression and Extends Survival in Models of Inherited ALS
- (2013) Kevin D Foust et al. MOLECULAR THERAPY
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- Mechanisms, models and biomarkers in amyotrophic lateral sclerosis
- (2013) Martin R. Turner et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
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- (2011) Matthew C Kiernan et al. LANCET
- Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis
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- Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1G93A mice model
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- Modification of Superoxide Dismutase 1 (SOD1) Properties by a GFP Tag – Implications for Research into Amyotrophic Lateral Sclerosis (ALS)
- (2010) James C. Stevens et al. PLoS One
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- Oxidative stress biomarkers in sporadic ALS
- (2008) Hiroshi Mitsumoto et al. Amyotrophic Lateral Sclerosis
- Design, power, and interpretation of studies in the standard murine model of ALS
- (2008) Sean Scott et al. Amyotrophic Lateral Sclerosis
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