The University of Pennsylvania glioblastoma (UPenn-GBM) cohort: advanced MRI, clinical, genomics, & radiomics

Radiomics analysis for predicting pembrolizumab response in patients with advanced rare cancers

(2021) Rivka R Colen et al.   Journal for ImmunoTherapy of Cancer

cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas

(2020) Daniel J. Brat et al.   ACTA NEUROPATHOLOGICA

Histopathology‐validated machine learning radiographic biomarker for noninvasive discrimination between true progression and pseudo‐progression in glioblastoma

(2020) Hamed Akbari et al.   CANCER

cIMPACT‐NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT‐Utrecht meeting on future CNS tumor classification and grading

(2020) David N. Louis et al.   BRAIN PATHOLOGY

AI-based prognostic imaging biomarkers for precision neuro-oncology: the ReSPOND consortium

(2020) Christos Davatzikos et al.   NEURO-ONCOLOGY

The Image Biomarker Standardization Initiative: Standardized Quantitative Radiomics for High-Throughput Image-based Phenotyping

(2020) Alex Zwanenburg et al.   RADIOLOGY

Integrated Biophysical Modeling and Image Analysis: Application to Neuro-Oncology

(2020) Andreas Mang et al.   Annual Review of Biomedical Engineering

iGLASS: Imaging integration into the Glioma Longitudinal AnalySiS Consortium

(2020) S Bakas et al.   NEURO-ONCOLOGY

Brain extraction on MRI scans in presence of diffuse glioma: Multi-institutional performance evaluation of deep learning methods and robust modality-agnostic training

(2020) Siddhesh Thakur et al.   NEUROIMAGE

cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAFV600E mutation

(2019) David W. Ellison et al.   ACTA NEUROPATHOLOGICA

Precision diagnostics based on machine learning-derived imaging signatures

(2019) Christos Davatzikos et al.   MAGNETIC RESONANCE IMAGING

Computational staining of unlabelled tissue

(2019) Spyridon Bakas et al.   Nature Biomedical Engineering

Imaging signatures of glioblastoma molecular characteristics: A radiogenomics review

(2019) Anahita Fathi Kazerooni et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Longitudinal brain tumor segmentation prediction in MRI using feature and label fusion

(2019) Linmin Pei et al.   Biomedical Signal Processing and Control

Multivariate Analysis of Preoperative Magnetic Resonance Imaging Reveals Transcriptomic Classification of de novo Glioblastoma Patients

(2019) Saima Rathore et al.   Frontiers in Computational Neuroscience

cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3 K27M-mutant and diffuse astrocytoma/anaplastic astrocytoma, IDH-mutant

(2018) David N. Louis et al.   ACTA NEUROPATHOLOGICA

cIMPACT-NOW update 1: Not Otherwise Specified (NOS) and Not Elsewhere Classified (NEC)

(2018) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development

(2018) Zev A. Binder et al.   CANCER CELL

In vivo evaluation of EGFRvIII mutation in primary glioblastoma patients via complex multiparametric MRI signature

(2018) Hamed Akbari et al.   NEURO-ONCOLOGY

User-Guided Segmentation of Multi-modality Medical Imaging Datasets with ITK-SNAP

(2018) Paul A. Yushkevich et al.   NEUROINFORMATICS

ACRIN 6684: Multicenter, phase II assessment of tumor hypoxia in newly diagnosed glioblastoma using magnetic resonance spectroscopy

(2018) Eva-Maria Ratai et al.   PLoS One

An anatomic transcriptional atlas of human glioblastoma

(2018) Ralph B. Puchalski et al.   SCIENCE

Radiogenomic analysis of hypoxia pathway is predictive of overall survival in Glioblastoma

(2018) Niha Beig et al.   Scientific Reports

Radiomic MRI signature reveals three distinct subtypes of glioblastoma with different clinical and molecular characteristics, offering prognostic value beyond IDH1

(2018) Saima Rathore et al.   Scientific Reports

cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”

(2018) Daniel J. Brat et al.   ACTA NEUROPATHOLOGICA

Non-invasive determination of the O6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation status in glioblastoma (GBM) using magnetic resonance imaging (MRI).

(2018) Saima Rathore et al.   JOURNAL OF CLINICAL ONCOLOGY

NIMG-40. NON-INVASIVE IN VIVO SIGNATURE OF IDH1 MUTATIONAL STATUS IN HIGH GRADE GLIOMA, FROM CLINICALLY-ACQUIRED MULTI-PARAMETRIC MAGNETIC RESONANCE IMAGING, USING MULTIVARIATE MACHINE LEARNING

(2018) Spyridon Bakas et al.   NEURO-ONCOLOGY

Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma

(2017) Roger Stupp et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Efficient multi-scale 3D CNN with fully connected CRF for accurate brain lesion segmentation

(2017) Konstantinos Kamnitsas et al.   MEDICAL IMAGE ANALYSIS

NIMG-41. ACCURATE AND GENERALIZABLE PRE-OPERATIVE PROGNOSTIC STRATIFICATION OF GLIOBLASTOMA PATIENTS USING INTEGRATIVE QUANTITATIVE RADIOMIC ANALYSIS OF CONVENTIONAL MRI

(2017) Spyridon Bakas et al.   NEURO-ONCOLOGY

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

ACRIN 6684: Assessment of Tumor Hypoxia in Newly Diagnosed Glioblastoma Using 18F-FMISO PET and MRI

(2016) E. R. Gerstner et al.   CLINICAL CANCER RESEARCH

The first step for neuroimaging data analysis: DICOM to NIfTI conversion

(2016) Xiangrui Li et al.   JOURNAL OF NEUROSCIENCE METHODS

Clonal evolution of glioblastoma under therapy

(2016) Jiguang Wang et al.   NATURE GENETICS

DRES-04. TUMOR HETEROGENEITY CONTRIBUTES TO RESISTANCE TO ANTI-EGFR THERAPY IN GLIOBLASTOMA

(2016) Ciro Zanca et al.   NEURO-ONCOLOGY

CSIG-22. MUTATIONAL HETEROGENEITY OF THE EGFR EXTRACELLULAR DOMAIN PROMOTES AN ONCOGENIC UNTETHERED TRANSITIONAL CONFORMATION AND THE POTENTIAL FOR GREATER THERAPEUTIC TARGETING IN GBM PATIENTS

(2016) Amy Haseley Thorne et al.   NEURO-ONCOLOGY

NIMG-20. IMAGING PATTERN ANALYSIS REVEALS THREE DISTINCT PHENOTYPIC SUBTYPES OF GBM WITH DIFFERENT SURVIVAL RATES

(2016) Saima Rathore et al.   NEURO-ONCOLOGY

MPTH-02. EXTRACELLULAR EGFR289 ACTIVATING MUTATIONS CONFER POORER SURVIVAL AND SUGGEST ENHANCED MOTILITY IN PRIMARY GBMs

(2016) Zev Binder et al.   NEURO-ONCOLOGY

NIMG-11. HIGHLY-EXPRESSED WILD-TYPE EGFR AND EGFRvIII MUTANT GLIOBLASTOMAS HAVE SIMILAR MRI SIGNATURE, CONSISTENT WITH DEEP PERITUMORAL INFILTRATION

(2016) Spyridon Bakas et al.   NEURO-ONCOLOGY

Imaging Surrogates of Infiltration Obtained Via Multiparametric Imaging Pattern Analysis Predict Subsequent Location of Recurrence of Glioblastoma

(2016) Hamed Akbari et al.   NEUROSURGERY

The FAIR Guiding Principles for scientific data management and stewardship

(2016) Mark D. Wilkinson et al.   Scientific Data

Co-occurrence of Local Anisotropic Gradient Orientations (CoLlAGe): A new radiomics descriptor

(2016) Prateek Prasanna et al.   Scientific Reports

Repeatability of Standardized and Normalized Relative CBV in Patients with Newly Diagnosed Glioblastoma

(2015) M.A. Prah et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

The Multimodal Brain Tumor Image Segmentation Benchmark (BRATS)

(2015) Bjoern H. Menze et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Addition of MR imaging features and genetic biomarkers strengthens glioblastoma survival prediction in TCGA patients

(2015) Manal Nicolasjilwan et al.   JOURNAL OF NEURORADIOLOGY

Imaging patterns predict patient survival and molecular subtype in glioblastoma via machine learning techniques

(2015) Luke Macyszyn et al.   NEURO-ONCOLOGY

Intratumoral heterogeneity in glioblastoma: don't forget the peritumoral brain zone

(2015) Jean-Michel Lemée et al.   NEURO-ONCOLOGY

Magnetic resonance image features identify glioblastoma phenotypic subtypes with distinct molecular pathway activities

(2015) Haruka Itakura et al.   Science Translational Medicine

Repeatability of Cerebral Perfusion Using Dynamic Susceptibility Contrast MRI in Glioblastoma Patients

(2015) Kourosh Jafari-Khouzani et al.   Translational Oncology

The Epileptic Thalamocortical Network is a Macroscopic Self-Sustained Oscillator: Evidence from Frequency-Locking Experiments in Rat Brains

(2015) J. L. Perez Velazquez et al.   Scientific Reports

Radiogenomics: What It Is and Why It Is Important

(2015) Maciej A. Mazurowski   Journal of the American College of Radiology

Association of overall survival in patients with newly diagnosed glioblastoma with contrast-enhanced perfusion MRI: Comparison of intraindividually matched T1- and T2*-based bolus techniques

(2014) David Bonekamp et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Molecular and cellular heterogeneity: the hallmark of glioblastoma

(2014) Diane J. Aum et al.   Neurosurgical Focus

Pattern Analysis of Dynamic Susceptibility Contrast-enhanced MR Imaging Demonstrates Peritumoral Tissue Heterogeneity

(2014) Hamed Akbari et al.   RADIOLOGY

Outcome Prediction in Patients with Glioblastoma by Using Imaging, Clinical, and Genomic Biomarkers: Focus on the Nonenhancing Component of the Tumor

(2014) Rajan Jain et al.   RADIOLOGY

Glioblastoma Multiforme: Exploratory Radiogenomic Analysis by Using Quantitative Image Features

(2014) Olivier Gevaert et al.   RADIOLOGY

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

(2014) A. P. Patel et al.   SCIENCE

ITK: enabling reproducible research and open science

(2014) Matthew McCormick et al.   Frontiers in Neuroinformatics

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered

(2013) Hui K. Gan et al.   FEBS Journal

SHAPE AND TEXTURE INDEXES APPLICATION TO CELL NUCLEI CLASSIFICATION

(2013) GUILLAUME THIBAULT et al.   INTERNATIONAL JOURNAL OF PATTERN RECOGNITION AND ARTIFICIAL INTELLIGENCE

The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository

(2013) Kenneth Clark et al.   JOURNAL OF DIGITAL IMAGING

Early post-bevacizumab progression on contrast-enhanced MRI as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 Central Reader Study

(2013) J. L. Boxerman et al.   NEURO-ONCOLOGY

Imaging descriptors improve the predictive power of survival models for glioblastoma patients

(2013) M. A. Mazurowski et al.   NEURO-ONCOLOGY

Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics

(2013) A. Sottoriva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MR Imaging Predictors of Molecular Profile and Survival: Multi-institutional Study of the TCGA Glioblastoma Data Set

(2013) David A. Gutman et al.   RADIOLOGY

A hitchhiker's guide to diffusion tensor imaging

(2013) José M. Soares et al.   Frontiers in Neuroscience

Probabilistic Radiographic Atlas of Glioblastoma Phenotypes

(2012) B.M. Ellingson et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

EGFRvIII gene rearrangement is an early event in glioblastoma tumorigenesis and expression defines a hierarchy modulated by epigenetic mechanisms

(2012) C A Del Vecchio et al.   ONCOGENE

Imaging and Genomics: Is There a Synergy?

(2012) C. Carl Jaffe   RADIOLOGY

Mosaic Amplification of Multiple Receptor Tyrosine Kinase Genes in Glioblastoma

(2011) Matija Snuderl et al.   CANCER CELL

Radiogenomic Mapping of Edema/Cellular Invasion MRI-Phenotypes in Glioblastoma Multiforme

(2011) Pascal O. Zinn et al.   PLoS One

N4ITK: Improved N3 Bias Correction

(2010) Nicholas J Tustison et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Radiogenomics: Creating a link between molecular diagnostics and diagnostic imaging

(2009) Aaron M. Rutman et al.   EUROPEAN JOURNAL OF RADIOLOGY

Comparison of Dynamic Susceptibility-weighted Contrast-enhanced MR Methods: Recommendations for Measuring Relative Cerebral Blood Volume in Brain Tumors

(2008) Eric S. Paulson et al.   RADIOLOGY