Role of Caveolin-1 in Sepsis – A Mini-Review

Role of Lipid Rafts in Pathogen-Host Interaction - A Mini Review

(2022) Rakesh Kulkarni et al.   Frontiers in Immunology

Multiple subregions within the caveolin-1 scaffolding domain inhibit fibrosis, microvascular leakage, and monocyte migration

(2022) Charles F. Reese et al.   PLoS One

Dexmedetomidine attenuates lipopolysaccharide-induced acute liver injury in rats by inhibiting caveolin-1 downstream signaling pathway

(2021) Fei Tong et al.   BIOSCIENCE REPORTS

Campylobacter jejuni Cytolethal Distending Toxin C Exploits Lipid Rafts to Mitigate Helicobacter pylori-Induced Pathogenesis

(2021) Jia-Yin Yeh et al.   Frontiers in Cell and Developmental Biology

Resveratrol Attenuates Meningitic Escherichia coli-Mediated Blood–Brain Barrier Disruption

(2021) Ruicheng Yang et al.   ACS Infectious Diseases

Notoginsenoside R1 intervenes degradation and redistribution of tight junctions to ameliorate blood-brain barrier permeability by Caveolin-1/MMP2/9 pathway after acute ischemic stroke

(2021) Bowen Liu et al.   PHYTOMEDICINE

Matrix lumican endocytosed by immune cells controls receptor ligand trafficking to promote TLR4 and restrict TLR9 in sepsis

(2021) George Maiti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pravastatin attenuates sepsis-induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of Cav-1/eNOS pathway

(2021) Yi Ren et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

P2X7 receptor activation increases expression of caveolin-1 and formation of macrophage lipid rafts, thereby boosting CD39 activity

(2020) Luiz Eduardo Baggio Savio et al.   JOURNAL OF CELL SCIENCE

Early-Onset Neonatal Sepsis 2015 to 2017, the Rise of Escherichia coli, and the Need for Novel Prevention Strategies

(2020) Barbara J. Stoll et al.   JAMA Pediatrics

Structural Similarity with Cholesterol Reveals Crucial Insights into Mechanisms Sustaining the Immunomodulatory Activity of the Mycotoxin Alternariol

(2020) Giorgia Del Favero et al.   Cells

Cav-1 (Caveolin-1) Deficiency Increases Autophagy in the Endothelium and Attenuates Vascular Inflammation and Atherosclerosis

(2020) Xinbo Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Differential expression of caveolin-1 during pathogenesis of combined pulmonary fibrosis and emphysema: Effect of phosphodiesterase-5 inhibitor

(2020) R. Kulshrestha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Pulmonary Innate Immune Response Determines the Outcome of Inflammation During Pneumonia and Sepsis-Associated Acute Lung Injury

(2020) Vijay Kumar   Frontiers in Immunology

Occludin, caveolin‐1, and Alix form a multi‐protein complex and regulate HIV‐1 infection of brain pericytes

(2020) Silvia Torices et al.   FASEB JOURNAL

Signaling Pathways Involved in the Development of Bronchopulmonary Dysplasia and Pulmonary Hypertension

(2020) Rajamma Mathew   Children-Basel

Autophagy alleviates hypoxia-induced blood-brain barrier injury via regulation of CLDN5 (claudin 5)

(2020) Zhenguo Yang et al.   Autophagy

Caveolin-1, tetraspanin CD81 and flotillins in lymphocyte cell membrane organization, signaling and immunopathology

(2020) Anna-Maria Schaffer et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling

(2020) Neng Wang et al.   Frontiers in Pharmacology

Caveolin-1 in autophagy: A potential therapeutic target in atherosclerosis

(2020) Kai Hou et al.   CLINICA CHIMICA ACTA

Caveolae: Mechanosensing and mechanotransduction devices linking membrane trafficking to mechanoadaptation

(2020) Miguel A. Del Pozo et al.   CURRENT OPINION IN CELL BIOLOGY

Caveolae, caveolin-1 and lung diseases of aging

(2019) Sarah A. Wicher et al.   Expert Review of Respiratory Medicine

Caveolin‐1 regulates human trabecular meshwork cell adhesion, endocytosis, and autophagy

(2019) Zhenggen Wu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Axin-1 binds to Caveolin-1 to regulate the LPS-induced inflammatory response in AT-I cells

(2019) Yongjuan Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Caveolin-1 Regulates Atherogenesis by Attenuating Low-Density Lipoprotein Transcytosis and Vascular Inflammation Independently of Endothelial Nitric Oxide Synthase Activation

(2019) Cristina M. Ramírez et al.   CIRCULATION

Caveolin‐1 knockdown increases the therapeutic sensitivity of lung cancer to cisplatin‐induced apoptosis by repressing Parkin‐related mitophagy and activating the ROCK1 pathway

(2019) Yi Liu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

SPIONs enhances IL-10-producing macrophages to relieve sepsis via Cav1-Notch1/HES1-mediated autophagy

(2019) Yujun Xu et al.   International Journal of Nanomedicine

Trichomonas vaginalis extracellular vesicles are internalized by host cells using proteoglycans and caveolin-dependent endocytosis

(2019) Anand Kumar Rai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caveolin-1 deficiency protects pancreatic β cells against palmitate-induced dysfunction and apoptosis

(2018) Wen Zeng et al.   CELLULAR SIGNALLING

T cells and their immunometabolism: a novel way to understanding sepsis immunopathogenesis and future therapeutics

(2018) V. Kumar   EUROPEAN JOURNAL OF CELL BIOLOGY

Ox-LDL induces endothelial cell apoptosis and macrophage migration by regulating caveolin-1 phosphorylation

(2018) Fei Lin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Autophagy- and MMP-2/9-mediated Reduction and Redistribution of ZO-1 Contribute to Hyperglycemia-increased Blood–Brain Barrier Permeability During Early Reperfusion in Stroke

(2018) Shuai Zhang et al.   NEUROSCIENCE

Hostʼs Endogenous Caveolin-1 Expression is Downregulated in the Lung During Sepsis to Promote Cytoprotection

(2018) Agapi Kataki et al.   SHOCK

Shear stress augments mitochondrial ATP generation that triggers ATP release and Ca2+ signaling in vascular endothelial cells

(2018) Kimiko Yamamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Deletion of caveolin-1 attenuates LPS/GalN-induced acute liver injury in mice

(2018) Tsung-Huang Tsai et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Sepsis: developing new alternatives to reduce neuroinflammation and attenuate brain injury

(2018) Gabriela Meneses et al.   Annals of the New York Academy of Sciences

Inhibition of c-Src protects paraquat induced microvascular endothelial injury by modulating caveolin-1 phosphorylation and caveolae mediated transcellular permeability

(2017) Yu Huang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Caveolin-1 Influences LFA-1 Redistribution upon TCR Stimulation in CD8 T Cells

(2017) Jessica G. Borger et al.   JOURNAL OF IMMUNOLOGY

Lung epithelial cells: therapeutically inducible effectors of antimicrobial defense

(2017) M M Leiva-Juárez et al.   Mucosal Immunology

Vascular heterogeneity and specialization in development and disease

(2017) Michael Potente et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Macrophage-like nanoparticles concurrently absorbing endotoxins and proinflammatory cytokines for sepsis management

(2017) Soracha Thamphiwatana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Caveolin 1 in HIV Infection and Pathogenesis

(2017) Ayalew Mergia   Viruses-Basel

Caveolin1 Is Required for Th1 Cell Infiltration, but Not Tight Junction Remodeling, at the Blood-Brain Barrier in Autoimmune Neuroinflammation

(2017) Sarah E. Lutz et al.   Cell Reports

Sepsis and septic shock: New definitions, new diagnostic and therapeutic approaches

(2017) Silvano Esposito et al.   Journal of Global Antimicrobial Resistance

Caveolin-1 facilitates internalization and degradation of ABCA1 and probucol oxidative products interfere with this reaction to increase HDL biogenesis

(2016) Rui Lu et al.   ATHEROSCLEROSIS

Caveolin-1 contributes to realgar nanoparticle therapy in human chronic myelogenous leukemia K562 cells

(2016) Dan Shi et al.   International Journal of Nanomedicine

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Nucleoside diphosphate kinase B regulates angiogenic responses in the endothelium via caveolae formation and c-Src-mediated caveolin-1 phosphorylation

(2016) Shalini Gross et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dexmedetomidine may upregulate the expression of caveolin-1 in lung tissues of rats with sepsis and improve the short-term outcome

(2016) Yun Zhang et al.   Molecular Medicine Reports

The Endothelium in Sepsis

(2016) Can Ince et al.   SHOCK

Overexpression of caveolin-1 attenuates brain edema by inhibiting tight junction degradation

(2016) Kang-Ho Choi et al.   Oncotarget

Critical role of CAV1/caveolin-1 in cell stress responses in human breast cancer cells via modulation of lysosomal function and autophagy

(2015) Yin Shi et al.   Autophagy

Autophagy Mediates Tolerance to Staphylococcus aureus Alpha-Toxin

(2015) Katie Maurer et al.   Cell Host & Microbe

Combinatorial Therapy with Acetylation and Methylation Modifiers Attenuates Lung Vascular Hyperpermeability in Endotoxemia-Induced Mouse Inflammatory Lung Injury

(2014) Jayakumar Thangavel et al.   AMERICAN JOURNAL OF PATHOLOGY

Loss of caveolin-1 and adiponectin induces severe inflammatory lung injury following LPS challenge through excessive oxidative/nitrative stress

(2014) Lei Cai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Nucleoside Diphosphate Kinase B Regulates Angiogenesis Through Modulation of Vascular Endothelial Growth Factor Receptor Type 2 and Endothelial Adherens Junction Proteins

(2014) Yuxi Feng et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hypoxic Trophoblast HMGB1 Induces Endothelial Cell Hyperpermeability via the TRL-4/Caveolin-1 Pathway

(2014) Rongzhen Jiang et al.   JOURNAL OF IMMUNOLOGY

Caveolin-1 Mediates Salmonella Invasion via the Regulation of SopE-dependent Rac1 Activation and Actin Reorganization

(2014) Jae Sung Lim et al.   JOURNAL OF INFECTIOUS DISEASES

Role of caveolin-1 in asthma and chronic inflammatory respiratory diseases

(2014) Simon G Royce et al.   Expert Review of Respiratory Medicine

Caveolin-1 Tyr14 Phosphorylation Induces Interaction with TLR4 in Endothelial Cells and Mediates MyD88-Dependent Signaling and Sepsis-Induced Lung Inflammation

(2013) H. Jiao et al.   JOURNAL OF IMMUNOLOGY

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Caveolin-1 abrogates TGF-β mediated hepatocyte apoptosis

(2013) C Meyer et al.   Cell Death & Disease

The role of caveolae in the pathophysiology of lung diseases

(2013) Michael A Thompson et al.   Expert Review of Respiratory Medicine

Caveolin-1 Plays a Critical Role in the Differentiation of Monocytes into Macrophages

(2012) Yi Fu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Caveolin-1 plays a critical role in host immunity against Klebsiella pneumoniae by regulating STAT5 and Akt activity

(2012) Qiang Guo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Caveolin-1 opens endothelial cell junctions by targeting catenins

(2011) Romy Kronstein et al.   CARDIOVASCULAR RESEARCH

Caveolin-1 Orchestrates TCR Synaptic Polarity, Signal Specificity, and Function in CD8 T Cells

(2011) T. Tomassian et al.   JOURNAL OF IMMUNOLOGY

Caveolin-1 Deficiency Dampens Toll-Like Receptor 4 Signaling through eNOS Activation

(2010) Muhammad K. Mirza et al.   AMERICAN JOURNAL OF PATHOLOGY

Caveolin-1 Protects against Sepsis by Modulating Inflammatory Response, Alleviating Bacterial Burden, and Suppressing Thymocyte Apoptosis

(2010) Hong Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudomonas aeruginosa

(2009) Milan Bajmoczi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Caveolin-1 Modifies the Immunity to Pseudomonas aeruginosa

(2009) Mihaela Gadjeva et al.   JOURNAL OF IMMUNOLOGY

Immunodesign of experimental sepsis by cecal ligation and puncture

(2009) Daniel Rittirsch et al.   Nature Protocols

Deletion of Cavin/PTRF Causes Global Loss of Caveolae, Dyslipidemia, and Glucose Intolerance

(2008) Libin Liu et al.   Cell Metabolism

Apoptosis in Sepsis: Mechanisms, Clinical Impact and Potential Therapeutic Targets

(2008) Alfred Ayala et al.   CURRENT PHARMACEUTICAL DESIGN

Repression of BK Virus Infection of Human Renal Proximal Tubular Epithelial Cells by Pravastatin

(2008) Takahito Moriyama et al.   TRANSPLANTATION

Neutrophil caveolin-1 expression contributes to mechanism of lung inflammation and injury

(2007) Guochang Hu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY