Highly sensitive Curcumin-conjugated nanotheranostic platform for detecting amyloid-beta plaques by magnetic resonance imaging and reversing cognitive deficits of Alzheimer's disease via NLRP3-inhibition

Brain regional pharmacokinetics following the oral administration of curcumagalactomannosides and its relation to cognitive function

(2021) Ramalingam G. Kannan et al.   NUTRITIONAL NEUROSCIENCE

NIR/MRI‐Guided Oxygen‐Independent Carrier‐Free Anti‐Tumor Nano‐Theranostics

(2021) Di Gao et al.   Small

Defect self-assembly of metal-organic framework triggers ferroptosis to overcome resistance

(2021) Haibao Peng et al.   Bioactive Materials

Modulating autophagic flux via ROS-responsive targeted micelles to restore neuronal proteostasis in Alzheimer's disease

(2021) Shuting Xu et al.   Bioactive Materials

Microglia in Alzheimer’s disease: Local heroes!

(2020) Nàdia Villacampa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NLRP3 inflammasome activity as biomarker for primary progressive multiple sclerosis

(2020) Sarah Lemprière   Nature Reviews Neurology

β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia

(2020) Lea L. Friker et al.   Cell Reports

Oxford Brain Diagnostics: turning MRI into a diagnosis tool for dementia

(2020) Simon Makin   NATURE

Co-Administration of Iron and a Bioavailable Curcumin Supplement Increases Serum BDNF Levels in Healthy Adults

(2020) Helena Tiekou Lorinczova et al.   Antioxidants

Immunogenic-cell-killing and immunosuppression-inhibiting nanomedicine

(2020) Ying Wang et al.   Bioactive Materials

Structure-Relaxivity Relationships of Magnetic Nanoparticles for Magnetic Resonance Imaging

(2019) Zijian Zhou et al.   ADVANCED MATERIALS

Targeting the transferrin receptor for brain drug delivery

(2019) Kasper Bendix Johnsen et al.   PROGRESS IN NEUROBIOLOGY

Dendritic Cell-Activating Magnetic Nanoparticles Enable Early Prediction of Antitumor Response with Magnetic Resonance Imaging

(2019) Adam J. Grippin et al.   ACS Nano

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

(2019) Justin M. Long et al.   CELL

Synthesis Of PEG-Coated, Ultrasmall, Manganese-Doped Iron Oxide Nanoparticles With High Relaxivity For T1/T2 Dual-Contrast Magnetic Resonance Imaging

(2019) Shilin Xiao et al.   International Journal of Nanomedicine

What Is Dementia?

(2019) Zoe Arvanitakis et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Diagnosis and Management of Dementia: Review

(2019) Zoe Arvanitakis et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Targeting the microglial NLRP3 inflammasome and its role in Parkinson's disease

(2019) Md. Ezazul Haque et al.   MOVEMENT DISORDERS

MRI-Visible siRNA Nanomedicine Directing Neuronal Differentiation of Neural Stem Cells in Stroke

(2018) Liejing Lu et al.   ADVANCED FUNCTIONAL MATERIALS

Upregulation of NLRP3 via STAT3-dependent histone acetylation contributes to painful neuropathy induced by bortezomib

(2018) Cui-Cui Liu et al.   EXPERIMENTAL NEUROLOGY

Developmental origins of adult health and disease: The metabolic role of BDNF from early life to adulthood

(2018) Despina D. Briana et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Molecular Magnetic Resonance Imaging of Endothelial Activation in the Central Nervous System

(2018) Maxime Gauberti et al.   Theranostics

Biomimetic nanoparticles for inflammation targeting

(2018) Kai Jin et al.   Acta Pharmaceutica Sinica B

Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases

(2018) Denzil Furtado et al.   ADVANCED MATERIALS

SPION-Enhanced Magnetic Resonance Imaging of Alzheimer's Disease Plaques in AβPP/PS-1 Transgenic Mouse Brain

(2018) Laurel O. Sillerud et al.   JOURNAL OF ALZHEIMERS DISEASE

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model

(2018) Se Hoon Choi et al.   SCIENCE

Magnetic Nanomaterials for Advanced Regenerative Medicine: The Promise and Challenges

(2018) Xiao-Li Liu et al.   ADVANCED MATERIALS

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

In vitro screening of nanomedicines through the blood brain barrier: A critical review

(2016) Juan Aparicio-Blanco et al.   BIOMATERIALS

Graphene quantum dots conjugated neuroprotective peptide improve learning and memory capability

(2016) Songhua Xiao et al.   BIOMATERIALS

Targeted Drug Delivery with Polymers and Magnetic Nanoparticles: Covalent and Noncovalent Approaches, Release Control, and Clinical Studies

(2016) Karel Ulbrich et al.   CHEMICAL REVIEWS

Blood–brain barrier shuttle peptides: an emerging paradigm for brain delivery

(2016) Benjamí Oller-Salvia et al.   CHEMICAL SOCIETY REVIEWS

Superparamagnetic nanoparticle-enhanced MRI of Alzheimer's disease plaques and activated microglia in 3X transgenic mouse brains: Contrast optimization

(2016) Marissa A. Tafoya et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Nanotheranostics: Congo Red/Rutin-MNPs with Enhanced Magnetic Resonance Imaging and H2O2-Responsive Therapy of Alzheimer's Disease in APPswe/PS1dE9 Transgenic Mice

(2015) Bingbing Hu et al.   ADVANCED MATERIALS

Curcumin-conjugated magnetic nanoparticles for detecting amyloid plaques in Alzheimer's disease mice using magnetic resonance imaging (MRI)

(2015) Kwok Kin Cheng et al.   BIOMATERIALS

DSPE-PEG: A Distinctive Component in Drug Delivery System

(2015) Jing Che et al.   CURRENT PHARMACEUTICAL DESIGN

A validated LC-MS/MS method for quantitative analysis of curcumin in mouse plasma and brain tissue and its application in pharmacokinetic and brain distribution studies

(2014) Prakash Ramalingam et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer’s Disease Model via Canonical Wnt/β-Catenin Pathway

(2013) Shashi Kant Tiwari et al.   ACS Nano

Indocyanine green loaded SPIO nanoparticles with phospholipid-PEG coating for dual-modal imaging and photothermal therapy

(2013) Yan Ma et al.   BIOMATERIALS

Dual-functional nanoparticles targeting amyloid plaques in the brains of Alzheimer's disease mice

(2013) Chi Zhang et al.   BIOMATERIALS

Nano-magnetic particles used in biomedicine: Core and coating materials

(2013) Z. Karimi et al.   Materials Science & Engineering C-Materials for Biological Applications

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Self-Assembly of Phospholipid–PEG Coating on Nanoparticles through Dual Solvent Exchange

(2011) Sheng Tong et al.   NANO LETTERS

Detection of amyloid plaques targeted by USPIO-Aβ1–42 in Alzheimer's disease transgenic mice using magnetic resonance microimaging

(2011) Jing Yang et al.   NEUROIMAGE

Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma

(2010) Fernanda I. Staquicini et al.   JOURNAL OF CLINICAL INVESTIGATION

Manganese ferrite nanoparticle micellar nanocomposites as MRI contrast agent for liver imaging

(2009) Jian Lu et al.   BIOMATERIALS

Differently Selected d-Enantiomeric Peptides Act on Different Aβ Species

(2009) Dirk Bartnik et al.   REJUVENATION RESEARCH

In vitro and in vivo Staining Characteristics of Small, Fluorescent, Aβ42-Binding D-Enantiomeric Peptides in Transgenic AD Mouse Models

(2008) Thomas van Groen et al.   ChemMedChem

HT22 hippocampal neuronal cell line possesses functional cholinergic properties

(2008) Jun Liu et al.   LIFE SCIENCES