Towards a unified model of naive T cell dynamics across the lifespan

Cell-density independent increased lymphocyte production and loss rates post-autologous HSCT

(2021) Mariona Baliu-Piqué et al.   eLife

The naive T-cell receptor repertoire has an extremely broad distribution of clone sizes

(2020) Peter C de Greef et al.   eLife

Fate mapping reveals the age structure of the peripheral T cell compartment

(2019) Arnold Reynaldi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell generation dynamics underlying naive T-cell homeostasis in adult humans

(2019) Jeff E. Mold et al.   PLOS BIOLOGY

Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cell memory

(2019) Thea Hogan et al.   eLife

Developmental Origin Governs CD8 + T Cell Fate Decisions during Infection

(2018) Norah L. Smith et al.   CELL

Age is not just a number: Naive T cells increase their ability to persist in the circulation over time

(2018) Sanket Rane et al.   PLOS BIOLOGY

Ki67 is a Graded Rather than a Binary Marker of Proliferation versus Quiescence

(2018) Iain Miller et al.   Cell Reports

A new mechanism shapes the naïve CD8 + T cell repertoire: the selection for full diversity

(2017) Pedro Gonçalves et al.   MOLECULAR IMMUNOLOGY

Memory CD4 T cell subsets are kinetically heterogeneous and replenished from naive T cells at high levels

(2017) Graeme Gossel et al.   eLife

Dynamics of Recent Thymic Emigrants in Young Adult Mice

(2017) Vera van Hoeven et al.   Frontiers in Immunology

Fetal and adult progenitors give rise to unique populations of CD8+ T cells

(2016) J. Wang et al.   BLOOD

Practical Bayesian model evaluation using leave-one-out cross-validation and WAIC

(2016) Aki Vehtari et al.   STATISTICS AND COMPUTING

Temporal fate mapping reveals age-linked heterogeneity in naive T lymphocytes in mice

(2015) Thea Hogan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele

(2014) O. Basak et al.   EMBO JOURNAL

Mathematical Modeling Reveals the Biological Program Regulating Lymphopenia-Induced Proliferation

(2014) A. Yates et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Contact with Secondary Lymphoid Organs Drives Postthymic T Cell Maturation

(2014) E. G. Houston et al.   JOURNAL OF IMMUNOLOGY

Diversity and clonal selection in the human T-cell repertoire

(2014) Q. Qi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clonally Diverse T Cell Homeostasis Is Maintained by a Common Program of Cell-Cycle Control

(2013) T. Hogan et al.   JOURNAL OF IMMUNOLOGY

Homeostatic Properties and Phenotypic Maturation of Murine CD4+ Pre-Thymic Emigrants in the Thymus

(2013) Jie Dong et al.   PLoS One

Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans

(2012) Ineke den Braber et al.   IMMUNITY

Derivation and Maintenance of Virtual Memory CD8 T Cells

(2012) A. D. Akue et al.   JOURNAL OF IMMUNOLOGY

Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age

(2012) P. L. F. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent thymic emigrants are preferentially incorporated only into the depleted T-cell pool

(2011) E. G. Houston et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bim Dictates Naive CD4 T Cell Lifespan and the Development of Age-Associated Functional Defects

(2010) H. Tsukamoto et al.   JOURNAL OF IMMUNOLOGY

Convergent recombination shapes the clonotypic landscape of the naive T-cell repertoire

(2010) M. F. Quigley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects

(2009) H. Tsukamoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA