Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age

Clonal Expansions and Loss of Receptor Diversity in the Naive CD8 T Cell Repertoire of Aged Mice

(2014) M. Ahmed et al.   JOURNAL OF IMMUNOLOGY

Determinants of public T cell responses

(2012) Hanjie Li et al.   CELL RESEARCH

Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans

(2012) Ineke den Braber et al.   IMMUNITY

Age-related changes in CD8 T cell homeostasis and immunity to infection

(2012) Janko Nikolich-Žugich et al.   SEMINARS IN IMMUNOLOGY

Exhaustive T-cell repertoire sequencing of human peripheral blood samples reveals signatures of antigen selection and a directly measured repertoire size of at least 1 million clonotypes

(2011) R. L. Warren et al.   GENOME RESEARCH

A Mechanism for TCR Sharing between T Cell Subsets and Individuals Revealed by Pyrosequencing

(2011) Vanessa Venturi et al.   JOURNAL OF IMMUNOLOGY

Evolution of the Antigen-Specific CD8+ TCR Repertoire across the Life Span: Evidence for Clonal Homogenization of the Old TCR Repertoire

(2011) B. D. Rudd et al.   JOURNAL OF IMMUNOLOGY

Recent thymic emigrants are preferentially incorporated only into the depleted T-cell pool

(2011) E. G. Houston et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions

(2011) B. D. Rudd et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overlap and Effective Size of the Human CD8+ T Cell Receptor Repertoire

(2010) H. S. Robins et al.   Science Translational Medicine

Quantifying Thymic Export: Combining Models of Naive T Cell Proliferation and TCR Excision Circle Dynamics Gives an Explicit Measure of Thymic Output

(2009) I. Bains et al.   JOURNAL OF IMMUNOLOGY

Thymic involution and immune reconstitution

(2009) Heather E. Lynch et al.   TRENDS IN IMMUNOLOGY

T cell subset-specific susceptibility to aging

(2008) Marta Czesnikiewicz-Guzik et al.   CLINICAL IMMUNOLOGY

Growth hormone enhances thymic function in HIV-1–infected adults

(2008) Laura A. Napolitano et al.   JOURNAL OF CLINICAL INVESTIGATION

Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool

(2008) N. Vrisekoop et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA