Hypoxia controls plasma membrane targeting of polarity proteins by dynamic turnover of PI4P and PI(4,5)P2

Electrostatic plasma membrane targeting contributes to Dlg function in cell polarity and tumorigenesis

(2021) Juan Lu et al.   DEVELOPMENT

Probing the subcellular distribution of phosphatidylinositol reveals a surprising lack at the plasma membrane

(2020) James P. Zewe et al.   JOURNAL OF CELL BIOLOGY

Defining the subcellular distribution and metabolic channeling of phosphatidylinositol

(2020) Joshua G. Pemberton et al.   JOURNAL OF CELL BIOLOGY

Novel roles of phosphoinositides in signaling, lipid transport, and disease

(2020) Gerald R.V. Hammond et al.   CURRENT OPINION IN CELL BIOLOGY

A PI4KIIIα protein complex is required for cell viability during Drosophila wing development

(2020) Urbashi Basu et al.   DEVELOPMENTAL BIOLOGY

A polybasic domain in aPKC mediates Par6-dependent control of membrane targeting and kinase activity

(2020) Wei Dong et al.   JOURNAL OF CELL BIOLOGY

Escherichia coli as a platform for the study of phosphoinositide biology

(2019) Sergio Botero et al.   Science Advances

Phosphatidylinositol 4,5‐bisphosphate controls Rab7 and PLEKMH1 membrane cycling during autophagosome–lysosome fusion

(2019) Takashi Baba et al.   EMBO JOURNAL

PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism

(2019) Diana G. Wang et al.   Cell Reports

RGB-Color Intensiometric Indicators to Visualize Spatiotemporal Dynamics of ATP in Single Cells

(2018) Satoshi Arai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PI(4,5)P2controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites

(2018) Mira Sohn et al.   JOURNAL OF CELL BIOLOGY

Genetic dissection of the phosphoinositide cycle inDrosophilaphotoreceptors

(2018) Che-Hsiung Liu et al.   JOURNAL OF CELL SCIENCE

Regulation of PI4P levels by PI4KIIIα during G-protein coupled PLC signaling inDrosophilaphotoreceptors

(2018) Sruthi S. Balakrishnan et al.   JOURNAL OF CELL SCIENCE

Genetically encoded lipid biosensors

(2018) Rachel C. Wills et al.   MOLECULAR BIOLOGY OF THE CELL

An efficient and multiple target transgenic RNAi technique with low toxicity in Drosophila

(2018) Huan-Huan Qiao et al.   Nature Communications

Mitochondrial dysfunction induces dendritic loss via eIF2α phosphorylation

(2017) Taiichi Tsuyama et al.   JOURNAL OF CELL BIOLOGY

RASSF4 controls SOCE and ER–PM junctions through regulation of PI(4,5)P2

(2017) Yu-Ju Chen et al.   JOURNAL OF CELL BIOLOGY

Architecture of the human PI4KIIIα lipid kinase complex

(2017) Joshua A. Lees et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P

(2016) Rui Dong et al.   CELL

A phosphoinositide conversion mechanism for exit from endosomes

(2016) Katharina Ketel et al.   NATURE

Phosphoinositide signalling in Drosophila

(2015) Sruthi S. Balakrishnan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Establishment of Par-Polarized Cortical Domains via Phosphoregulated Membrane Motifs

(2015) Matthew J. Bailey et al.   DEVELOPMENTAL CELL

Plasticity of PI4KIII  interactions at the plasma membrane

(2015) J. Chung et al.   EMBO REPORTS

A conserved polybasic domain mediates plasma membrane targeting of Lgl and its regulation by hypoxia

(2015) Wei Dong et al.   JOURNAL OF CELL BIOLOGY

The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane

(2015) Jeremy M. Baskin et al.   NATURE CELL BIOLOGY

PI(4,5)P2 Produced by the PI4P5K SKTL Controls Apical Size by Tethering PAR-3 in Drosophila Epithelial Cells

(2014) Sandra Claret et al.   CURRENT BIOLOGY

A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi

(2014) Gerald R.V. Hammond et al.   JOURNAL OF CELL BIOLOGY

PI4KIII  is required for cortical integrity and cell polarity during Drosophila oogenesis

(2014) J. Tan et al.   JOURNAL OF CELL SCIENCE

Golgi and plasma membrane pools of PI(4)P contribute to plasma membrane PI(4,5)P2 and maintenance of KCNQ2/3 ion channel current

(2014) E. J. Dickson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Insights into Assembly and Regulation of the Plasma Membrane Phosphatidylinositol 4-Kinase Complex

(2013) Xudong Wu et al.   DEVELOPMENTAL CELL

Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation

(2013) Tamas Balla   PHYSIOLOGICAL REVIEWS

Evaluation of intramitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation

(2013) H. Kioka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila

(2012) J. Burgess et al.   DEVELOPMENT

PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity

(2012) Fubito Nakatsu et al.   JOURNAL OF CELL BIOLOGY

PI4P and PI(4,5)P2 Are Essential But Independent Lipid Determinants of Membrane Identity

(2012) G. R. V. Hammond et al.   SCIENCE

Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling

(2011) Y. Yan et al.   DEVELOPMENT

Differential regulation of adherens junction dynamics during apical-basal polarization

(2011) J. Huang et al.   JOURNAL OF CELL SCIENCE

An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis

(2009) Gregory D. Fairn et al.   JOURNAL OF CELL BIOLOGY

Dual roles for theDrosophilaPI 4-kinase Four wheel drive in localizing Rab11 during cytokinesis

(2009) Gordon Polevoy et al.   JOURNAL OF CELL BIOLOGY

Directed, efficient, and versatile modifications of the Drosophila genome by genomic engineering

(2009) J. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

(2009) H. Imamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PIP5K-dependent production of PIP2 sustains microtubule organization to establish polarized transport in the Drosophila oocyte

(2008) L. Gervais et al.   DEVELOPMENT

Rolling blackout is required for bulk endocytosis in non-neuronal cells and neuronal synapses

(2008) N. Vijayakrishnan et al.   JOURNAL OF CELL SCIENCE

Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

(2008) T. Yeung et al.   SCIENCE