MULTI-SCULPT: Multiplex Integration via Selective, CRISPR-Mediated, Ultralong Pathway Transformation in Yeast for Plant Natural Product Synthesis

Natural products in drug discovery: advances and opportunities

(2021) Atanas G. Atanasov et al.   NATURE REVIEWS DRUG DISCOVERY

Metabolic Engineering of Isoflavones: An Updated Overview

(2021) Soo In Sohn et al.   Frontiers in Plant Science

Engineering Saccharomyces cerevisiae Coculture Platform for the Production of Flavonoids

(2020) Yun Du et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Discovery and engineering of colchicine alkaloid biosynthesis

(2020) Ryan S. Nett et al.   NATURE

Biosynthesis of medicinal tropane alkaloids in yeast

(2020) Prashanth Srinivasan et al.   NATURE

COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors

(2019) Gita Naseri et al.   Nature Communications

Deciphering eukaryotic gene-regulatory logic with 100 million random promoters

(2019) Carl G. de Boer et al.   NATURE BIOTECHNOLOGY

mpCRISTAR: Multiple Plasmid Approach for CRISPR/Cas9 and TAR-Mediated Multiplexed Refactoring of Natural Product Biosynthetic Gene Clusters

(2019) Hiyoung Kim et al.   ACS Synthetic Biology

Involvement of chalcone reductase (CHR) in the soybean isoflavone metabolon: Identification of GmCHR5 that interacts with 2-hydroxyisoflavanone synthase

(2018) Ryo Mameda et al.   PLANT JOURNAL

Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle

(2018) Lorenzo Caputi et al.   SCIENCE

A highly efficient single-step, markerless strategy for multi-copy chromosomal integration of large biochemical pathways in Saccharomyces cerevisiae

(2016) Shuobo Shi et al.   METABOLIC ENGINEERING

Evaluation of Biosynthetic Pathway and Engineered Biosynthesis of Alkaloids

(2016) Shinji Kishimoto et al.   MOLECULES

The Traditional Medicine and Modern Medicine from Natural Products

(2016) Haidan Yuan et al.   MOLECULES

Twin anchors of the soybean isoflavonoid metabolon: evidence for tethering of the complex to the endoplasmic reticulum by IFS and C4H

(2016) Mehran Dastmalchi et al.   PLANT JOURNAL

De novo production of the plant-derived alkaloid strictosidine in yeast

(2015) Stephanie Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complete biosynthesis of opioids in yeast

(2015) S. Galanie et al.   SCIENCE

A Highly Characterized Yeast Toolkit for Modular, Multipart Assembly

(2015) Michael E. Lee et al.   ACS Synthetic Biology

CasEMBLR: Cas9-Facilitated Multiloci Genomic Integration of in Vivo Assembled DNA Parts in Saccharomyces cerevisiae

(2015) Tadas Jakočiu̅nas et al.   ACS Synthetic Biology

Short Synthetic Terminators for Improved Heterologous Gene Expression in Yeast

(2015) Kathleen A. Curran et al.   ACS Synthetic Biology

Soybean chalcone isomerase: evolution of the fold, and the differential expression and localization of the gene family

(2014) Mehran Dastmalchi et al.   PLANTA

Efficient bioethanol production by overexpression of endogenous Saccharomyces cerevisiae xylulokinase and NADPH-dependent aldose reductase with mutated strictly NADP+-dependent Pichia stipitis xylitol dehydrogenase

(2014) Sadat Mohammad Rezq Khattab et al.   PROCESS BIOCHEMISTRY

Homology-Integrated CRISPR–Cas (HI-CRISPR) System for One-Step Multigene Disruption in Saccharomyces cerevisiae

(2014) Zehua Bao et al.   ACS Synthetic Biology

Characterization of 582 natural and synthetic terminators and quantification of their design constraints

(2013) Ying-Ja Chen et al.   NATURE METHODS

Metabolic engineering of recombinant protein secretion by Saccharomyces cerevisiae

(2012) Jin Hou et al.   FEMS YEAST RESEARCH

DEVELOPING A YEAST CELL FACTORY FOR THE PRODUCTION OF TERPENOIDS

(2012) Sotirios C. Kampranis et al.   Computational and Structural Biotechnology Journal

Metabolic engineering of monoterpene synthesis in yeast

(2011) Marc J. C. Fischer et al.   BIOTECHNOLOGY AND BIOENGINEERING

Harnessing yeast subcellular compartments for the production of plant terpenoids

(2011) Moran Farhi et al.   METABOLIC ENGINEERING

Functional Analysis of the Arabidopsis PAL Gene Family in Plant Growth, Development, and Response to Environmental Stress

(2010) J. Huang et al.   PLANT PHYSIOLOGY

Natural products in crop protection

(2009) Franck E. Dayan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Production of Genistein from Naringenin Using Escherichia coli Containing Isoflavone Synthase-Cytochrome P450 Reductase Fusion Protein

(2009) Dae Hwan Kim   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Differential expression of CHS7 and CHS8 genes in soybean

(2009) Jinxin Yi et al.   PLANTA

Characterization of chromosomal integration sites for heterologous gene expression inSaccharomyces cerevisiae

(2009) Dongmei Bai Flagfeldt et al.   YEAST

DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways

(2008) Zengyi Shao et al.   NUCLEIC ACIDS RESEARCH

Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma genitalium Genome

(2008) D. G. Gibson et al.   SCIENCE

Pervasive and Persistent Redundancy among Duplicated Genes in Yeast

(2008) E. Jedediah Dean et al.   PLoS Genetics