Bivalent metal ions induce formation of α-synuclein fibril polymorphs with different cytotoxicities

Inhibiting mTTR Aggregation/Fibrillation by a Chaperone-like Hydrophobic Amino Acid-Conjugated SPION

(2022) Payam Arghavani et al.   JOURNAL OF PHYSICAL CHEMISTRY B

The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells

(2021) Roberta Cascella et al.   Nature Communications

Remodeling of the Fibrillation Pathway of α‐Synuclein by Interaction with Antimicrobial Peptide LL‐III

(2021) Rosario Oliva et al.   CHEMISTRY-A EUROPEAN JOURNAL

A study on the interaction of the amyloid fibrils of α-synuclein and hen egg white lysozyme with biological membranes

(2021) Ramin Zadali et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Naturally occurring cinnamic acid derivatives prevent amyloid transformation of alpha-synuclein

(2020) Maria Medvedeva et al.   BIOCHIMIE

Alpha-Synuclein Amyloid Aggregation Is Inhibited by Sulfated Aromatic Polymers and Pyridinium Polycation

(2020) Pavel Semenyuk et al.   Polymers

α-Synuclein fibrillation products trigger the release of hexokinase I from mitochondria: Protection by curcumin, and possible role in pathogenesis of Parkinson's disease

(2020) Ziba Dehghani et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Inhibition of aggregation and toxicity of α-synuclein in the presence of copper by an N-methylated peptide

(2020) Binbin Zhou et al.   JOURNAL OF MOLECULAR STRUCTURE

Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity

(2020) Amberley D. Stephens et al.   Nature Communications

α-synuclein interaction with zero-valent iron nanoparticles accelerates structural rearrangement into amyloid-susceptible structure with increased cytotoxic tendency

(2019) Seyedeh Sahar Tahaei Gilan et al.   International Journal of Nanomedicine

Characterizing the inhibition of α‐synuclein oligomerization by a pharmacological chaperone that prevents prion formation by the protein PrP

(2019) Chunhua Dong et al.   PROTEIN SCIENCE

C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction

(2018) Janin Lautenschläger et al.   Nature Communications

Molecular Role of Ca2+ and Hard Divalent Metal Cations on Accelerated Fibrillation and Interfibrillar Aggregation of α-Synuclein

(2018) Jong Yoon Han et al.   Scientific Reports

Evidence for Intramolecular Antiparallel Beta-Sheet Structure in Alpha-Synuclein Fibrils from a Combination of Two-Dimensional Infrared Spectroscopy and Atomic Force Microscopy

(2017) Steven J. Roeters et al.   Scientific Reports

Inhibition of HEWL fibril formation by taxifolin: Mechanism of action

(2017) Mohsen Mahdavimehr et al.   PLoS One

Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1

(2016) Michel Brahic et al.   ACTA NEUROPATHOLOGICA

Enterolactone: A novel radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis

(2016) Bahareh Bigdeli et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inhibition of amyloid fibrillation and cytotoxicity of lysozyme fibrillation products by polyphenols

(2015) Sajad Shariatizi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Obtaining information about protein secondary structures in aqueous solution using Fourier transform IR spectroscopy

(2015) Huayan Yang et al.   Nature Protocols

Multiple-System Atrophy

(2015) Alessandra Fanciulli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural basis behind the interaction of Zn2+ with the protein α-synuclein and the Aβ peptide: A comparative analysis

(2012) Ariel A. Valiente-Gabioud et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

(2011) Ulrike K Resenberger et al.   EMBO JOURNAL

Bioinorganic Chemistry of Parkinson’s Disease: Structural Determinants for the Copper-Mediated Amyloid Formation of Alpha-Synuclein

(2010) Andrés Binolfi et al.   INORGANIC CHEMISTRY

Site-Specific Interactions of Cu(II) with α and β-Synuclein: Bridging the Molecular Gap between Metal Binding and Aggregation

(2008) Andrés Binolfi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper(II) Binding to α-Synuclein, the Parkinson’s Protein

(2008) Jennifer C. Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Calcium(II) selectively induces α-synuclein annular oligomers via interaction with the C-terminal domain

(2004) Rachel Lowe et al.   PROTEIN SCIENCE