FAK mediates LPS-induced inflammatory lung injury through interacting TAK1 and activating TAK1-NFκB pathway

NF-κB Signaling in Macrophages: Dynamics, Crosstalk, and Signal Integration

(2019) Michael G. Dorrington et al.   Frontiers in Immunology

Shikonin inhibits myeloid differentiation protein 2 to prevent LPS-induced acute lung injury

(2018) Yali Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Recent progress in the discovery of myeloid differentiation 2 (MD2) modulators for inflammatory diseases

(2018) Lingfeng Chen et al.   DRUG DISCOVERY TODAY

Acute Lung Injury: A Clinical and Molecular Review

(2016) Yasmeen Butt et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Acute respiratory distress syndrome

(2016) C. Mason et al.   CLINICAL MEDICINE

Initial testing of VS-4718, a novel inhibitor of focal adhesion kinase (FAK), against pediatric tumor models by the Pediatric Preclinical Testing Program

(2016) Raushan T. Kurmasheva et al.   PEDIATRIC BLOOD & CANCER

Pharmacological Inhibition of Focal Adhesion Kinase Attenuates Cardiac Fibrosis in Mice Cardiac Fibroblast and Post-Myocardial-Infarction Models

(2015) Guang-Pu Fan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Lipopolysaccharide Regulation of Intestinal Tight Junction Permeability Is Mediated by TLR4 Signal Transduction Pathway Activation of FAK and MyD88

(2015) Shuhong Guo et al.   JOURNAL OF IMMUNOLOGY

Antifibrotic Effects of Focal Adhesion Kinase Inhibitor in Bleomycin-Induced Pulmonary Fibrosis in Mice

(2013) Katsuhiro Kinoshita et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cell type-specific function of TAK1 in innate immune signaling

(2013) Adebusola A. Ajibade et al.   TRENDS IN IMMUNOLOGY

Targeting Focal Adhesion Kinase in Fibrotic Diseases

(2012) David Lagares et al.   BIODRUGS

Evaluation and Discovery of Novel Synthetic Chalcone Derivatives as Anti-Inflammatory Agents

(2011) Jianzhang Wu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Early Identification of Patients at Risk of Acute Lung Injury

(2010) Ognjen Gajic et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Clinical Characteristics and Outcomes of Sepsis-Related vs Non-Sepsis-Related ARDS

(2010) Chau-Chyun Sheu et al.   CHEST

Acute Lung Injury: Epidemiology, Pathogenesis, and Treatment

(2010) Elizabeth R. Johnson et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Focal adhesion kinase modulates activation of NF-κB by flow in endothelial cells

(2009) Tobias Petzold et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Requirement of transforming growth factor β-activated kinase 1 for transforming growth factor β-induced α-smooth muscle actin expression and extracellular matrix contraction in fibroblasts

(2009) Xu Shi-Wen et al.   ARTHRITIS AND RHEUMATISM

Recent trends in acute lung injury mortality: 1996–2005*

(2009) Sara E. Erickson et al.   CRITICAL CARE MEDICINE

Animal models of acute lung injury

(2008) Gustavo Matute-Bello et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY