Short chain fatty acid, acetate restores ovarian function in experimentally induced PCOS rat model

Luteolin alleviates polycystic ovary syndrome in rats by resolving insulin resistance and oxidative stress

(2021) Yue Huang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Acetate rescues defective brain-adipose metabolic network in obese Wistar rats by modulation of peroxisome proliferator-activated receptor-γ

(2021) Kehinde Samuel Olaniyi et al.   Scientific Reports

Sildenafil ameliorates leptin resistance and normalizes lipid handling in the hypothalamic and adipose tissues of testosterone-exposed pregnant rats

(2021) Emmanuel Damilare Areola et al.   Heliyon

Repression of HDAC5 by acetate restores hypothalamic-pituitary-ovarian function in type 2 diabetes mellitus

(2021) Kehinde S. Olaniyi et al.   REPRODUCTIVE TOXICOLOGY

Spironolactone reversed hepato-ovarian triglyceride accumulation caused by letrozole-induced polycystic ovarian syndrome: tissue uric acid—a familiar foe

(2020) Oluwaseun A. Adeyanju et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Metabolic Dysfunction in Polycystic Ovary Syndrome: Pathogenic Role of Androgen Excess and Potential Therapeutic Strategies

(2020) Miguel A. Sanchez-Garrido et al.   Molecular Metabolism

Sodium acetate-mediated inhibition of histone deacetylase alleviates hepatic lipid dysregulation and its accompanied injury in streptozotocin-nicotinamide-induced diabetic rats

(2020) Kehinde S. Olaniyi et al.   BIOMEDICINE & PHARMACOTHERAPY

Low dose spironolactone-mediated androgen-adiponectin modulation alleviates endocrine-metabolic disturbances in letrozole-induced PCOS

(2020) Kehinde S. Olaniyi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Upregulation of Cyp19a1 and PPAR-γ in ovarian steroidogenic pathway by Ficus religiosa: A potential cure for polycystic ovary syndrome

(2020) Udhayaraj Suriyakalaa et al.   JOURNAL OF ETHNOPHARMACOLOGY

Polycystic Ovary Syndrome

(2019) Kathleen M. Brennan et al.   OBSTETRICAL & GYNECOLOGICAL SURVEY

Detrimental effects of oxidative stress in bovine oocytes during intracytoplasmic sperm injection (ICSI)

(2019) Shiori Ashibe et al.   THERIOGENOLOGY

Sodium acetate protects against nicotine-induced excess hepatic lipid in male rats by suppressing xanthine oxidase activity

(2019) E.O. Dangana et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The Anti-inflammatory Effects of Short Chain Fatty Acids on Lipopolysaccharide- or Tumor Necrosis Factor α-Stimulated Endothelial Cells via Activation of GPR41/43 and Inhibition of HDACs

(2018) Meng Li et al.   Frontiers in Pharmacology

Investigation of Therapeutic Effects of Erdosteine on Polycystic Ovary Syndrome in a Rat Model

(2018) Atilla Karateke et al.   MEDICAL PRINCIPLES AND PRACTICE

Epigenetic Metabolite Acetate Inhibits Class I/II Histone Deacetylases, Promotes Histone Acetylation, and Increases HIV-1 Integration in CD4 + T Cells

(2017) Jean-François Bolduc et al.   JOURNAL OF VIROLOGY

Genes and proteins of the alternative steroid backdoor pathway for dihydrotestosterone synthesis are expressed in the human ovary and seem enhanced in the polycystic ovary syndrome

(2017) Nesa Marti et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Sodium butyrate activates NRF2 to ameliorate diabetic nephropathy possibly via inhibition of HDAC

(2016) Wenpeng Dong et al.   JOURNAL OF ENDOCRINOLOGY

High Serum Tumor Necrosis Factor-Alpha Levels in Women with Polycystic Ovary Syndrome: A Meta-Analysis

(2016) Lingling Gao et al.   PLoS One

Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome

(2015) Daniel A. Dumesic et al.   ENDOCRINE REVIEWS

The Utility of Metformin Therapy in Reproductive-Aged Women with Polycystic Ovary Syndrome (PCOS)

(2014) Nisha Nathan et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Characterization of Reproductive, Metabolic, and Endocrine Features of Polycystic Ovary Syndrome in Female Hyperandrogenic Mouse Models

(2014) A. S. L. Caldwell et al.   ENDOCRINOLOGY

Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR–S6K pathway

(2014) J Park et al.   Mucosal Immunology

Emerging role of epigenetics and miRNA in diabetic cardiomyopathy

(2012) Mohamed Asrih et al.   CARDIOVASCULAR PATHOLOGY

A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells

(2012) Fan Qu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Should all women with PCOS be treated for insulin resistance?

(2011) John C. Marshall et al.   FERTILITY AND STERILITY

Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage

(2011) Bing Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Polycystic ovary syndrome: etiology, pathogenesis and diagnosis

(2011) Mark O. Goodarzi et al.   Nature Reviews Endocrinology

One-Hour Plasma Glucose Identifies Insulin Resistance and  -Cell Dysfunction in Individuals With Normal Glucose Tolerance: Cross-sectional data from the Relationship between Insulin Sensitivity and Cardiovascular Risk (RISC) study

(2010) M. Manco et al.   DIABETES CARE

TNF: A master switch for inflammation to cancer

(2008) Gautam Sethi   Frontiers in Bioscience-Landmark

Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon

(2008) Markus Waldecker et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY