Exploring the Immunotherapeutic Potential of Oleocanthal against Murine Cutaneous Leishmaniasis

Total Phenolic Fraction (TPF) from Extra Virgin Olive Oil: Induction of apoptotic-like cell death in Leishmania spp. promastigotes and in vivo potential of therapeutic immunomodulation

(2021) Kalliopi Karampetsou et al.   PLoS Neglected Tropical Diseases

An Overview on the Therapeutics of Neglected Infectious Diseases—Leishmaniasis and Chagas Diseases

(2021) Brindha J et al.   Frontiers in Chemistry

Leishmanicidal potentials of Gossypium hirsutum extract and its fractions on Leishmania major in a murine model: parasite burden, gene expression, and histopathological profile

(2021) Fatemeh Sharifi et al.   JOURNAL OF MEDICAL MICROBIOLOGY

In vitro and in vivo therapeutic potentials of 6-gingerol in combination with amphotericin B for treatment of Leishmania major infection: Powerful synergistic and multifunctional effects

(2021) Alireza Keyhani et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Recent researches in effective antileishmanial herbal compounds: narrative review

(2020) Sahar Ghodsian et al.   PARASITOLOGY RESEARCH

An investigation of the effects of environmental and ecologic factors on cutaneous leishmaniasis in the old world: a systematic review study

(2020) Abolfazl Mohammadbeigi et al.   REVIEWS ON ENVIRONMENTAL HEALTH

Pilot continuous centrifugal liquid-liquid extraction of extra virgin olive oil biophenols and gram-scale recovery of pure oleocanthal, oleacein, MFOA, MFLA and hydroxytyrosol

(2020) Apostolis Angelis et al.   SEPARATION AND PURIFICATION TECHNOLOGY

(−)-Oleocanthal Combined with Lapatinib Treatment Synergized against HER-2 Positive Breast Cancer In Vitro and In Vivo

(2019) Abu Siddique et al.   Nutrients

(−)-Oleocanthal Prevents Breast Cancer Locoregional Recurrence After Primary Tumor Surgical Excision and Neoadjuvant Targeted Therapy in Orthotopic Nude Mouse Models

(2019) Abu Bakar Siddique et al.   Cancers

Novel liquid-liquid extraction and self-emulsion methods for simplified isolation of extra-virgin olive oil phenolics with emphasis on (-)-oleocanthal and its oral anti-breast cancer activity

(2019) Abu Bakar Siddique et al.   PLoS One

(-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells

(2019) Limor Goren et al.   PLoS One

Evaluation of total phenolic fraction derived from extra virgin olive oil for its antileishmanial activity

(2018) Olga S. Koutsoni et al.   PHYTOMEDICINE

The Biological Activities of Oleocanthal from a Molecular Perspective

(2018) Kok-Lun Pang et al.   Nutrients

Sambucus ebulus extract stimulates cellular responses in cutaneous leishmaniasis

(2018) Maryam Heidari-Kharaji et al.   PARASITE IMMUNOLOGY

The olive oil phenolic (-)-oleocanthal modulates estrogen receptor expression in luminal breast cancer in vitro and in vivo and synergizes with tamoxifen treatment

(2017) Nehad M. Ayoub et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

An integrated process for the recovery of high added-value compounds from olive oil using solid support free liquid-liquid extraction and chromatography techniques

(2017) Apostolis Angelis et al.   JOURNAL OF CHROMATOGRAPHY A

Lower levels of IgG1 in comparison with IgG2a are associated with protective immunity against Leishmania tropica infection in BALB/c mice

(2017) Mosayeb Rostamian et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Role of Mast Cells in clearance of Leishmania through extracellular trap formation

(2017) Nilofer Naqvi et al.   Scientific Reports

The Health Benefiting Mechanisms of Virgin Olive Oil Phenolic Compounds

(2016) Lisa Parkinson et al.   MOLECULES

The leishmanicidal activity of oleuropein is selectively regulated through inflammation- and oxidative stress-related genes

(2016) Ioannis D. Kyriazis et al.   Parasites & Vectors

Pro- and anti-inflammatory cytokines in cutaneous leishmaniasis: a review

(2016) Nahid Maspi et al.   Pathogens and Global Health

Therapeutic and immunomodulatory activities of short-course treatment of murine visceral leishmaniasis with KALSOME™10, a new liposomal amphotericin B

(2015) Mohammad Asad et al.   BMC INFECTIOUS DISEASES

Activity of olive leaf extracts against the promastigote stage of Leishmania species and their correlation with the antioxidant activity

(2014) Ines Sifaoui et al.   EXPERIMENTAL PARASITOLOGY

Oleocanthal, a Phenolic Derived from Virgin Olive Oil: A Review of the Beneficial Effects on Inflammatory Disease

(2014) Lisa Parkinson et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases

(2014) Stefania Bulotta et al.   Journal of Translational Medicine

In vitro effects of triterpenic acids from olive leaf extracts on the mitochondrial membrane potential of promastigote stage of Leishmania spp

(2014) Ines Sifaoui et al.   PHYTOMEDICINE

Olive Phenolics as c-Met Inhibitors: (-)-Oleocanthal Attenuates Cell Proliferation, Invasiveness, and Tumor Growth in Breast Cancer Models

(2014) Mohamed R. Akl et al.   PLoS One

Olive-Oil-Derived Oleocanthal Enhances β-Amyloid Clearance as a Potential Neuroprotective Mechanism against Alzheimer’s Disease: In Vitro and in Vivo Studies

(2013) Alaa H. Abuznait et al.   ACS Chemical Neuroscience

Further evidence for the anti-inflammatory activity of oleocanthal: Inhibition of MIP-1α and IL-6 in J774 macrophages and in ATDC5 chondrocytes

(2012) Morena Scotece et al.   LIFE SCIENCES

Tissue damage and immunity in cutaneous leishmaniasis

(2012) S. Nylén et al.   PARASITE IMMUNOLOGY

Intramuscular and topical treatment of cutaneous leishmaniasis lesions in mice infected with Leishmania amazonensis using coumarin (−) mammea A/BB

(2012) Tatiana Shioji Tiuman et al.   PHYTOMEDICINE

T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements

(2012) Aditi Kanhere et al.   Nature Communications

Accelerated healing of cutaneous leishmaniasis in non-healing BALB/c mice using water soluble amphotericin B-polymethacrylic acid

(2011) Karina Corware et al.   BIOMATERIALS