Activation of SIRT1 Alleviates Ferroptosis in the Early Brain Injury after Subarachnoid Hemorrhage

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Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects

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Hepcidin Promoted Ferroptosis through Iron Metabolism which Is Associated with DMT1 Signaling Activation in Early Brain Injury following Subarachnoid Hemorrhage

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Inhibition of Ferroptosis Alleviates Early Brain Injury After Subarachnoid Hemorrhage In Vitro and In Vivo via Reduction of Lipid Peroxidation

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Acyl‐CoA synthetase long chain family member 4 plays detrimental role in early brain injury after subarachnoid hemorrhage in rats by inducing ferroptosis

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Inhibition of BECN1 Suppresses Lipid Peroxidation by Increasing System Xc− Activity in Early Brain Injury after Subarachnoid Hemorrhage

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FSP1 is a glutathione-independent ferroptosis suppressor

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The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

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Cerebroprotection by salvianolic acid B after experimental subarachnoid hemorrhage occurs via Nrf2- and SIRT1-dependent pathways

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Astaxanthin mitigates subarachnoid hemorrhage injury primarily by increasing sirtuin 1 and inhibiting the Toll-like receptor 4 signaling pathway

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Role of GPX4 in ferroptosis and its pharmacological implication

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Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury

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Sirtuin 1 activation protects against early brain injury after experimental subarachnoid hemorrhage in rats

(2016) Xiang-Sheng Zhang et al.   Cell Death & Disease

Hydrogen Sulfide Ameliorates Early Brain Injury Following Subarachnoid Hemorrhage in Rats

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Amelioration of oxidative stress and protection against early brain injury by astaxanthin after experimental subarachnoid hemorrhage

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