Mutations in the 3'-PPT Lead to HIV-1 Replication without Integration

Mechanistic Analysis of the Broad Antiretroviral Resistance Conferred by HIV-1 Envelope Glycoprotein Mutations

(2021) Yuta Hikichi et al.   mBio

Mutations in the HIV-1 3′-Polypurine Tract and Integrase Strand Transfer Inhibitor Resistance

(2021) Yuliang Wei et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tax induces the recruitment of NF-kB to unintegrated HIV-1 DNA to rescue viral gene expression and replication

(2021) Ishak D. Irwan et al.   JOURNAL OF VIROLOGY

Specific mutations in the HIV-1 G-tract of the 3′-polypurine tract cause resistance to integrase strand transfer inhibitors

(2021) Atsuko Hachiya et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

INSTIs and NNRTIs Potently Inhibit HIV-1 Polypurine Tract Mutants in a Single Round Infection Assay

(2021) Steven J. Smith et al.   Viruses-Basel

Reversal of Epigenetic Silencing Allows Robust HIV-1 Replication in the Absence of Integrase Function

(2020) Ishak D. Irwan et al.   mBio

Human Immunodeficiency Virus Resistance to Dolutegravir: Are We Looking at the Wrong Place?

(2018) Gilles Darcis et al.   JOURNAL OF INFECTIOUS DISEASES

Mutations Located outside the Integrase Gene Can Confer Resistance to HIV-1 Integrase Strand Transfer Inhibitors

(2017) Isabelle Malet et al.   mBio

Different Pathways Leading to Integrase Inhibitors Resistance

(2017) Eloïse Thierry et al.   Frontiers in Microbiology

Dolutegravir as maintenance monotherapy for HIV (DOMONO): a phase 2, randomised non-inferiority trial

(2017) Ingeborg Wijting et al.   Lancet HIV

HIV-1 latency and virus production from unintegrated genomes following direct infection of resting CD4 T cells

(2016) Chi N. Chan et al.   Retrovirology

Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration

(2015) Sylvain Thierry et al.   Retrovirology

Once-daily dolutegravir versus darunavir plus ritonavir for treatment-naive adults with HIV-1 infection (FLAMINGO): 96 week results from a randomised, open-label, phase 3b study

(2015) Jean-Michel Molina et al.   Lancet HIV

Identification of Highly Conserved Residues Involved in Inhibition of HIV-1 RNase H Function by Diketo Acid Derivatives

(2014) Angela Corona et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An HIV-1 Replication Pathway Utilizing Reverse Transcription Products That Fail To Integrate

(2013) Benjamin Trinité et al.   JOURNAL OF VIROLOGY

Quantitative analysis of the time-course of viral DNA forms during the HIV-1 life cycle

(2013) Soundasse Munir et al.   Retrovirology

Evolution of HIV integrase resistance mutations

(2012) Peter K. Quashie et al.   CURRENT OPINION IN INFECTIOUS DISEASES

HIV Drug Resistance and the Advent of Integrase Inhibitors

(2012) Peter K. Quashie et al.   Current Infectious Disease Reports

The role of unintegrated DNA in HIV infection

(2011) Richard D Sloan et al.   Retrovirology

Notable Reduction in Illegitimate Integration Mediated by a PPT-deleted, Nonintegrating Lentiviral Vector

(2010) Boris Kantor et al.   MOLECULAR THERAPY