An HIV-1 Replication Pathway Utilizing Reverse Transcription Products That Fail To Integrate

A Doubly Fluorescent HIV-1 Reporter Shows that the Majority of Integrated HIV-1 Is Latent Shortly after Infection

(2013) M. S. Dahabieh et al.   JOURNAL OF VIROLOGY

Endothelial Cell Stimulation Overcomes Restriction and Promotes Productive and Latent HIV-1 Infection of Resting CD4+ T Cells

(2013) A. Shen et al.   JOURNAL OF VIROLOGY

Quantitative analysis of the time-course of viral DNA forms during the HIV-1 life cycle

(2013) Soundasse Munir et al.   Retrovirology

HIV restriction in quiescent CD4+ T cells

(2013) Jerome A Zack et al.   Retrovirology

HIV 2-long terminal repeat circular DNA is stable in primary CD4+T Cells

(2013) Matthew J. Pace et al.   VIROLOGY

Tracking episomal HIV DNA

(2013) Mark Sharkey   Current Opinion in HIV and AIDS

HIV Latency

(2013) R. F. Siliciano et al.   Cold Spring Harbor Perspectives in Medicine

HIV DNA Integration

(2013) R. Craigie et al.   Cold Spring Harbor Perspectives in Medicine

Interleukin-7 Facilitates HIV-1 Transmission to Cervico-Vaginal Tissue ex vivo

(2013) Andrea Introini et al.   PLoS Pathogens

Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies

(2013) Susanne Eriksson et al.   PLoS Pathogens

Integrated HIV DNA accumulates prior to treatment while episomal HIV DNA records ongoing transmission afterwards

(2012) John M. Murray et al.   AIDS

Concurrent measures of total and integrated HIV DNA monitor reservoirs and ongoing replication in eradication trials

(2012) Angela M. Mexas et al.   AIDS

The role of cytokines in the establishment, persistence and eradication of the HIV reservoir

(2012) Claire Vandergeeten et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Histone Deacetylase Inhibition Activates Transgene Expression from Integration-Defective Lentiviral Vectors in Dividing and Non-Dividing Cells

(2012) Laetitia P.L. Pelascini et al.   HUMAN GENE THERAPY

Redefining the Viral Reservoirs that Prevent HIV-1 Eradication

(2012) Evelyn Eisele et al.   IMMUNITY

Shock and kill

(2012) Steven G. Deeks   NATURE

Intrinsic antiviral immunity

(2012) Nan Yan et al.   NATURE IMMUNOLOGY

SAMHD1 restricts HIV-1 infection in resting CD4+ T cells

(2012) Hanna-Mari Baldauf et al.   NATURE MEDICINE

A Flexible Model of HIV-1 Latency Permitting Evaluation of Many Primary CD4 T-Cell Reservoirs

(2012) Kara G. Lassen et al.   PLoS One

Quantification of Unintegrated HIV-1 DNA at the Single Cell Level In Vivo

(2012) Rodolphe Suspène et al.   PLoS One

Developing strategies for HIV-1 eradication

(2012) Christine M. Durand et al.   TRENDS IN IMMUNOLOGY

Integrase-independent HIV-1 infection is augmented under conditions of DNA damage and produces a viral reservoir

(2012) Hirotaka Ebina et al.   VIROLOGY

A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: From nucleocapsid-condensed RNA to Vpr-bridged DNA

(2012) Sébastien Lyonnais et al.   VIRUS RESEARCH

The role of HIV-1 Vpr in promoting the infection of nondividing cells and in cell cycle arrest

(2012) Hamayun J. Sharifi et al.   Current Opinion in HIV and AIDS

HIV integrase as a target for antiretroviral therapy

(2012) Daria J. Hazuda   Current Opinion in HIV and AIDS

Impact of treatment with raltegravir during primary or chronic HIV infection on RNA decay characteristics and the HIV viral reservoir

(2011) Kersten K. Koelsch et al.   AIDS

HIV reservoirs and the possibility of a cure for HIV infection

(2011) S. Palmer et al.   JOURNAL OF INTERNAL MEDICINE

Vpr-Host Interactions During HIV-1 Viral Life Cycle

(2011) Richard Y. Zhao et al.   Journal of Neuroimmune Pharmacology

Multiploid Inheritance of HIV-1 during Cell-to-Cell Infection

(2011) A. Del Portillo et al.   JOURNAL OF VIROLOGY

HLA-DR+ CD38+ CD4+ T Lymphocytes Have Elevated CCR5 Expression and Produce the Majority of R5-Tropic HIV-1 RNA In Vivo

(2011) A. L. Meditz et al.   JOURNAL OF VIROLOGY

Rapid Turnover of 2-LTR HIV-1 DNA during Early Stage of Highly Active Antiretroviral Therapy

(2011) Weijun Zhu et al.   PLoS One

The role of unintegrated DNA in HIV infection

(2011) Richard D Sloan et al.   Retrovirology

The acute HIV infection: implications for intervention, prevention and development of an effective AIDS vaccine

(2011) Yoshiaki Nishimura et al.   Current Opinion in Virology

Elite Suppressors Harbor Low Levels of Integrated HIV DNA and High Levels of 2-LTR Circular HIV DNA Compared to HIV+ Patients On and Off HAART

(2011) Erin H. Graf et al.   PLoS Pathogens

Episomal Viral cDNAs Identify a Reservoir That Fuels Viral Rebound after Treatment Interruption and That Contributes to Treatment Failure

(2011) Mark Sharkey et al.   PLoS Pathogens

Early Events in Sexual Transmission of HIV and SIV and Opportunities for Interventions

(2010) Ashley T. Haase   Annual Review of Medicine

Molecular genetics of HBV infection

(2010) Stephen Locarnini et al.   ANTIVIRAL THERAPY

Bryostatin-1 Synergizes with Histone Deacetylase Inhibitors to Reactivate HIV-1 from Latency

(2010) Moises Perez et al.   CURRENT HIV RESEARCH

Targeting early infection to prevent HIV-1 mucosal transmission

(2010) Ashley T. Haase   NATURE

HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals

(2010) D. Trono et al.   SCIENCE

Patients on HAART often have an excess of unintegrated HIV DNA: Implications for monitoring reservoirs

(2010) Luis M. Agosto et al.   VIROLOGY

Histone deacetylase inhibitors and HIV latency

(2010) David M Margolis   Current Opinion in HIV and AIDS

HIV-1 Vpr: Regulator of Viral Survival

(2009) Khanh Thieu et al.   CURRENT HIV RESEARCH

Homeostatic proliferation and survival of naïve and memory T cells

(2009) Onur Boyman et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Measurement of Human Immunodeficiency Virus Type 1 Preintegration Transcription by Using Rev-Dependent Rev-CEM Cells Reveals a Sizable Transcribing DNA Population Comparable to That from Proviral Templates

(2009) S. R. Iyer et al.   JOURNAL OF VIROLOGY

Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs

(2009) Mayte Coiras et al.   NATURE REVIEWS MICROBIOLOGY

Synergistic Activation of HIV-1 Expression by Deacetylase Inhibitors and Prostratin: Implications for Treatment of Latent Infection

(2009) Sophie Reuse et al.   PLoS One

Epigenetic activation of unintegrated HIV-1 genomes by gut-associated short chain fatty acids and its implications for HIV infection

(2009) B. Kantor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High frequencies of resting CD4+ T cells containing integrated viral DNA are found in rhesus macaques during acute lentivirus infections

(2009) Y. Nishimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells

(2008) A. Bosque et al.   BLOOD

Non-Integrating Lentiviral Vectors

(2008) Chamsy Sarkis et al.   CURRENT GENE THERAPY

Dynamics of Total, Linear Nonintegrated, and Integrated HIV‐1 DNA In Vivo and In Vitro

(2008) Kersten K. Koelsch et al.   JOURNAL OF INFECTIOUS DISEASES

Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs

(2008) Lin Shen et al.   NATURE MEDICINE

HIV-1 Pre-Integration Complexes Selectively Target Decondensed Chromatin in the Nuclear Periphery

(2008) Alberto Albanese et al.   PLoS One

Viral complementation allows HIV-1 replication without integration

(2008) Huub C Gelderblom et al.   Retrovirology

Persistent transcription of a nonintegrating mutant of simian immunodeficiency virus in rhesus macrophages

(2007) Yanfang Zheng et al.   VIROLOGY

Human macrophages support persistent transcription from unintegrated HIV-1 DNA

(2007) Jeremy Kelly et al.   VIROLOGY