Engineered exosome-mediated delivery of circDIDO1 inhibits gastric cancer progression via regulation of MiR-1307-3p/SOCS2 Axis

Mesenchymal stem cell-originated exosomal circDIDO1 suppresses hepatic stellate cell activation by miR-141-3p/PTEN/AKT pathway in human liver fibrosis

(2022) Li Ma et al.   DRUG DELIVERY

Expanding uncapped translation and emerging function of circular RNA in carcinomas and noncarcinomas

(2022) Yan Wang et al.   Molecular Cancer

Circular RNA circLMO7 acts as a microRNA-30a-3p sponge to promote gastric cancer progression via the WNT2/β-catenin pathway

(2021) Jiacheng Cao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Treatment of Oxidative Stress with Exosomes in Myocardial Ischemia

(2021) Yun Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Extracellular vesicles as delivery systems at nano-/micro-scale

(2021) Peiwen Fu et al.   ADVANCED DRUG DELIVERY REVIEWS

Circular RNA ACTN4 promotes intrahepatic cholangiocarcinoma progression by recruiting YBX1 to initiate FZD7 transcription

(2021) Qinjunjie Chen et al.   JOURNAL OF HEPATOLOGY

A novel NF-κB regulator encoded by circPLCE1 inhibits colorectal carcinoma progression by promoting RPS3 ubiquitin-dependent degradation

(2021) Zhen-xing Liang et al.   Molecular Cancer

CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1-529aa protein and regulating PRDX2 protein stability

(2021) Yu Zhang et al.   Molecular Cancer

Circular RNA CircPPP1CB Suppresses Tumorigenesis by Interacting With the MiR-1307-3p/SMG1 Axis in Human Bladder Cancer

(2021) Feifan Wang et al.   Frontiers in Cell and Developmental Biology

Engineered exosomes for targeted co-delivery of miR-21 inhibitor and chemotherapeutics to reverse drug resistance in colon cancer

(2020) Gaofeng Liang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Extracellular Vesicle-Mediated Delivery of CircSCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models

(2020) Li Yang et al.   CIRCULATION

RNA delivery by extracellular vesicles in mammalian cells and its applications

(2020) Killian O’Brien et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Gastric cancer

(2020) Elizabeth C Smyth et al.   LANCET

Circular RNAs in cancer: Limitations in functional studies and diagnostic potential

(2020) Feiya Li et al.   SEMINARS IN CANCER BIOLOGY

circTADA2As suppress breast cancer progression and metastasis via targeting miR-203a-3p/SOCS3 axis

(2019) Jian-Zhen Xu et al.   Cell Death & Disease

The Landscape of Circular RNA in Cancer

(2019) Josh N. Vo et al.   CELL

MicroRNA-196a/-196b regulate the progression of hepatocellular carcinoma through modulating the JAK/STAT pathway via targeting SOCS2

(2019) Weihua Ren et al.   Cell Death & Disease

Mesenchymal stem cell-derived exosomes for clinical use

(2019) Mayela Mendt et al.   BONE MARROW TRANSPLANTATION

hsa_circ_0091570 acts as a ceRNA to suppress hepatocellular cancer progression by sponging hsa-miR-1307

(2019) Yu-Gang Wang et al.   CANCER LETTERS

The biogenesis, biology and characterization of circular RNAs

(2019) Lasse S. Kristensen et al.   NATURE REVIEWS GENETICS

Therapeutic targeting of circ‐ CUX 1 / EWSR 1/ MAZ axis inhibits glycolysis and neuroblastoma progression

(2019) Huanhuan Li et al.   EMBO Molecular Medicine

Circular RNA circ-RanGAP1 regulates VEGFA expression by targeting miR-877–3p to facilitate gastric cancer invasion and metastasis

(2019) Jun Lu et al.   CANCER LETTERS

CircNT5E acts as a sponge of microRNA-422a to promote glioblastoma tumorigenesis

(2018) Renjie Wang et al.   CANCER RESEARCH

The Effects of Cimetidine, N-Acetylcysteine, and Taurine on Thioridazine Metabolic Activation and Induction of Oxidative Stress in Isolated Rat Hepatocytes

(2018) Aziz Eftekhari et al.   PHARMACEUTICAL CHEMISTRY JOURNAL

Human Mesenchymal Stem Cell Derived Exosomes Alleviate Type 2 Diabetes Mellitus by Reversing Peripheral Insulin Resistance and Relieving β-Cell Destruction

(2018) Yaoxiang Sun et al.   ACS Nano

Synthetic circular RNA functions as a miR-21 sponge to suppress gastric carcinoma cell proliferation

(2018) Xi Liu et al.   Molecular Therapy-Nucleic Acids

In vivo β-catenin attenuation by the integrin α5-targeting nano-delivery strategy suppresses triple negative breast cancer stemness and metastasis

(2018) Yunfei Li et al.   BIOMATERIALS

Cis-acting circ-CTNNB1 promotes β-catenin signaling and cancer progression via DDX3-mediated transactivation of YY1

(2018) Feng Yang et al.   CANCER RESEARCH

Circular RNA circAGO2 drives cancer progression through facilitating HuR-repressed functions of AGO2-miRNA complexes

(2018) Yajun Chen et al.   CELL DEATH AND DIFFERENTIATION

Exosome-mediated delivery of functionally active miRNA-142-3p inhibitor reduces tumorigenicity of breast cancer in vitro and in vivo

(2018) Zahra Naseri et al.   International Journal of Nanomedicine

Recent advancements in the use of exosomes as drug delivery systems

(2018) Edwin J. Bunggulawa et al.   JOURNAL OF NANOBIOTECHNOLOGY

The use of RGD-engineered exosomes for enhanced targeting ability and synergistic therapy toward angiogenesis

(2017) Jie Wang et al.   Nanoscale

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

(2017) Sushrut Kamerkar et al.   NATURE

A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation

(2017) Y Chhabra et al.   ONCOGENE

Hepatoprotective and free radical scavenging actions of quercetin nanoparticles on aflatoxin B1-induced liver damage: in vitro/in vivo studies

(2017) Aziz Eftekhari et al.   Artificial Cells Nanomedicine and Biotechnology

Molecular classification of gastric cancer

(2016) N.-Y. Chia et al.   ANNALS OF ONCOLOGY

MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2

(2016) Rajdeep Das et al.   CANCER RESEARCH

Novel combination of serum microRNA for detecting breast cancer in the early stage

(2016) Akihiko Shimomura et al.   CANCER SCIENCE

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

(2016) William W. Du et al.   NUCLEIC ACIDS RESEARCH

Circular RNA Expression: Its Potential Regulation and Function

(2016) Julia Salzman   TRENDS IN GENETICS

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC

(2015) Benjamin Besse et al.   OncoImmunology

Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter

(2014) Charles P. Lai et al.   ACS Nano

Circular RNA and miR-7 in Cancer

(2013) T. B. Hansen et al.   CANCER RESEARCH

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials

(2012) Alexander V. Vlassov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS