MiR-106b-5p Attenuates Neuropathic Pain by Regulating the P2X4 Receptor in the Spinal Cord in Mice

miR-132-3p, miR-106b-5p, and miR-19b-3p Are Associated with Brain-Derived Neurotrophic Factor Production and Clinical Activity in Multiple Sclerosis: A Pilot Study

(2021) Fatma Sağır et al.   Genetic Testing and Molecular Biomarkers

MicroRNA-133b-3p Targets Purinergic P2X4 Receptor to Regulate Central Poststroke Pain in Rats

(2021) Xiaoning Guo et al.   NEUROSCIENCE

miR-106b-5p Inhibits IRF1/IFN-β Signaling to Promote M2 Macrophage Polarization of Glioblastoma

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miR-205 enhances radiation sensitivity of prostate cancer cells by impairing DNA damage repair through PKCε and ZEB1 inhibition

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Stimulation of nuclear receptor REV-ERBs suppresses production of pronociceptive molecules in cultured spinal astrocytes and ameliorates mechanical hypersensitivity of inflammatory and neuropathic pain of mice

(2019) Norimitsu Morioka et al.   BRAIN BEHAVIOR AND IMMUNITY

Zinc inhibited LPS-induced inflammatory responses by upregulating A20 expression in microglia BV2 cells

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P2X4 receptors, immunity, and sepsis

(2019) Luca Antonioli et al.   CURRENT OPINION IN PHARMACOLOGY

Role of the P2X4 receptor in neuropathic pain

(2019) Kazuhide Inoue   CURRENT OPINION IN PHARMACOLOGY

Inhibition of miR-200b/miR-429 contributes to neuropathic pain development through targeting zinc finger E box binding protein-1

(2018) Xue-Tao Yan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MiR-134-5p attenuates neuropathic pain progression through targeting Twist1

(2018) Li-Juan Ji et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

N A new central post-stroke pain rat model: autologous blood injected thalamic hemorrhage involved increased expression of P2X4 receptor

(2018) Hai-Feng Lu et al.   NEUROSCIENCE LETTERS

miR-124-3p attenuates neuropathic pain induced by chronic sciatic nerve injury in rats via targeting EZH2

(2018) Yang Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Identification of the Genome-wide Expression Patterns of Long Non-coding RNAs and mRNAs in Mice with Streptozotocin-induced Diabetic Neuropathic Pain

(2018) Huiying Du et al.   NEUROSCIENCE

MiR-34c Ameliorates Neuropathic Pain by Targeting NLRP3 in a Mouse Model of Chronic Constriction Injury

(2018) Lijuan Xu et al.   NEUROSCIENCE

Diabetes-induced Neuropathic Mechanical Hyperalgesia Depends on P2X4 Receptor Activation in Dorsal Root Ganglia

(2018) Juliana Maia Teixeira et al.   NEUROSCIENCE

IGF2BP3 functions as a potential oncogene and is a crucial target of miR-34a in gastric carcinogenesis

(2017) Yuhang Zhou et al.   Molecular Cancer

Toll-like receptor-4/p38 MAPK signaling in the dorsal horn contributes to P2X4 receptor activation and BDNF over-secretion in cancer induced bone pain

(2017) Xiao-wen Meng et al.   NEUROSCIENCE RESEARCH

Loss of GCN5 leads to increased neuronal apoptosis by upregulating E2F1- and Egr-1-dependent BH3-only protein Bim

(2017) Yanna Wu et al.   Cell Death & Disease

microRNA-761 induces aggressive phenotypes in triple-negative breast cancer cells by repressing TRIM29 expression

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The early growth response protein 1-miR-30a-5p-neurogenic differentiation factor 1 axis as a novel biomarker for schizophrenia diagnosis and treatment monitoring

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MiR-30b Attenuates Neuropathic Pain by Regulating Voltage-Gated Sodium Channel Nav1.3 in Rats

(2017) Songxue Su et al.   Frontiers in Molecular Neuroscience

P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology

(2017) Leanne Stokes et al.   Frontiers in Pharmacology

Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model

(2017) Agnieszka M. Jurga et al.   Frontiers in Pharmacology

miR-200b inhibits proliferation and metastasis of breast cancer by targeting fucosyltransferase IV and α1,3-fucosylated glycans

(2017) Q Zheng et al.   Oncogenesis

The role of miR-190a-5p contributes to diabetic neuropathic pain via targeting SLC17A6

(2017) Di Yang et al.   Journal of Pain Research

P2X4: A fast and sensitive purinergic receptor

(2017) Jaanus Suurväli et al.   Biomedical Journal

An Antagomir to MicroRNA-106b-5p Ameliorates Cerebral Ischemia and Reperfusion Injury in Rats Via Inhibiting Apoptosis and Oxidative Stress

(2016) Pengfei Li et al.   MOLECULAR NEUROBIOLOGY

Can Peripheral MicroRNA Expression Data Serve as Epigenomic (Upstream) Biomarkers of Alzheimer's Disease?

(2016) Şenay Görücü Yılmaz et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Duloxetine Inhibits Microglial P2X4 Receptor Function and Alleviates Neuropathic Pain after Peripheral Nerve Injury

(2016) Tomohiro Yamashita et al.   PLoS One

MiRNA203 suppresses the expression of protumorigenic STAT1 in glioblastoma to inhibit tumorigenesis

(2016) Chuan He Yang et al.   Oncotarget

Over-Expressed miR-224 Promotes the Progression of Cervical Cancer via Targeting RASSF8

(2016) YongJie Huang et al.   PLoS One

Altered microRNAs expression profiling in mice with diabetic neuropathic pain

(2015) Qingjuan Gong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Electroacupuncture inhibits excessive interferon-γ evoked up-regulation of P2X4 receptor in spinal microglia in a CCI rat model for neuropathic pain

(2015) X.-M. Chen et al.   BRITISH JOURNAL OF ANAESTHESIA

Genome-wide circulating microRNA expression profiling indicates biomarkers for epilepsy

(2015) Jun Wang et al.   Scientific Reports

Effects of dexmedetomidine on P2X4Rs, p38-MAPK and BDNF in spinal microglia in rats with spared nerve injury

(2014) Tian-tian Zhou et al.   BRAIN RESEARCH

Circulating MicroRNAs as Novel Potential Biomarkers for Early Diagnosis of Acute Stroke in Humans

(2014) Wanhua Wang et al.   Journal of Stroke & Cerebrovascular Diseases

Transcription factor IRF5 drives P2X4R+-reactive microglia gating neuropathic pain

(2014) Takahiro Masuda et al.   Nature Communications

CCL2 promotes P2X4 receptor trafficking to the cell surface of microglia

(2012) Emika Toyomitsu et al.   Purinergic Signalling

Neuronal CCL21 up-regulates microglia P2X4 expression and initiates neuropathic pain development

(2011) Knut Biber et al.   EMBO JOURNAL

ATP receptors gate microglia signaling in neuropathic pain

(2011) Tuan Trang et al.   EXPERIMENTAL NEUROLOGY

Purinergic systems, neuropathic pain and the role of microglia

(2011) Kazuhide Inoue et al.   EXPERIMENTAL NEUROLOGY

Mechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signalling pathways

(2009) Makoto Tsuda et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Role of mast cell activation in inducing microglial cells to release neurotrophin

(2009) Hongbin Yuan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Antidepressants Inhibit P2X4 Receptor Function: a Possible Involvement in Neuropathic Pain Relief

(2009) Kenichiro Nagata et al.   Molecular Pain

ATP induces long-term potentiation of C-fiber-evoked field potentials in spinal dorsal horn: The roles of P2X4receptors and p38 MAPK in microglia

(2008) Qing-Juan Gong et al.   GLIA

Up-Regulation of P2X4 Receptors in Spinal Microglia after Peripheral Nerve Injury Mediates BDNF Release and Neuropathic Pain

(2008) L. Ulmann et al.   JOURNAL OF NEUROSCIENCE

MicroRNA regulation of Alzheimer's Amyloid precursor protein expression

(2008) Sébastien S. Hébert et al.   NEUROBIOLOGY OF DISEASE