Loss of GCN5 leads to increased neuronal apoptosis by upregulating E2F1- and Egr-1-dependent BH3-only protein Bim
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Title
Loss of GCN5 leads to increased neuronal apoptosis by upregulating E2F1- and Egr-1-dependent BH3-only protein Bim
Authors
Keywords
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Journal
Cell Death & Disease
Volume 8, Issue 1, Pages e2570-e2570
Publisher
Springer Nature
Online
2017-01-26
DOI
10.1038/cddis.2016.465
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Note: Only part of the references are listed.- Melatonin attenuated early brain injury induced by subarachnoid hemorrhage via regulating NLRP3 inflammasome and apoptosis signaling
- (2016) Yushu Dong et al. JOURNAL OF PINEAL RESEARCH
- Control of genetic stability by a new heterochromatin compaction pathway involving the Tip60 histone acetyltransferase
- (2016) Aude Grézy et al. MOLECULAR BIOLOGY OF THE CELL
- Tozasertib attenuates neuronal apoptosis via DLK/JIP3/MA2K7/JNK pathway in early brain injury after SAH in rats
- (2016) Cheng Yin et al. NEUROPHARMACOLOGY
- Structural basis for histone H2B deubiquitination by the SAGA DUB module
- (2016) M. T. Morgan et al. SCIENCE
- Sirtuin 1 activation protects against early brain injury after experimental subarachnoid hemorrhage in rats
- (2016) Xiang-Sheng Zhang et al. Cell Death & Disease
- Role of the AMPK signaling pathway in early brain injury after subarachnoid hemorrhage in rats
- (2015) Ji-Yang An et al. ACTA NEUROCHIRURGICA
- Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression
- (2015) Frédéric Lebrun-Julien et al. ASN Neuro
- Intracellular translocation of histone deacetylase 5 regulates neuronal cell apoptosis
- (2015) Jia-Yi Wei et al. BRAIN RESEARCH
- HDAC2 Selectively Regulates FOXO3a-Mediated Gene Transcription during Oxidative Stress-Induced Neuronal Cell Death
- (2015) S. Peng et al. JOURNAL OF NEUROSCIENCE
- Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanism
- (2015) L. Formisano et al. JOURNAL OF NEUROSCIENCE
- Role of transcription factor acetylation in the regulation of metabolic homeostasis
- (2015) Joo-Man Park et al. Protein & Cell
- Interactive histone acetylation and methylation in regulating transdifferentiation-related genes during tunicate budding and regeneration
- (2014) Misa Shibuya et al. DEVELOPMENTAL DYNAMICS
- Regulation of cellular homoeostasis by reversible lysine acetylation: Figure 1.
- (2014) Iain Scott Essays in Biochemistry
- PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death
- (2014) Hyo-Kyoung Choi et al. HUMAN MOLECULAR GENETICS
- An RNA Binding Protein Promotes Axonal Integrity in Peripheral Neurons by Destabilizing REST
- (2014) F. Cargnin et al. JOURNAL OF NEUROSCIENCE
- Enhancement of Autophagy by Histone Deacetylase Inhibitor Trichostatin A Ameliorates Neuronal Apoptosis After Subarachnoid Hemorrhage in Rats
- (2014) Anwen Shao et al. MOLECULAR NEUROBIOLOGY
- MYC and EGR1 synergize to trigger tumor cell death by controlling NOXA and BIM transcription upon treatment with the proteasome inhibitor bortezomib
- (2014) Matthias Wirth et al. NUCLEIC ACIDS RESEARCH
- Role of p53 in cAMP/PKA pathway mediated apoptosis
- (2013) Ahmad Rahimi et al. APOPTOSIS
- Potential Roles of HDAC Inhibitors in Mitigating Ischemia-induced Brain Damage and Facilitating Endogenous Regeneration and Recovery
- (2013) Emily Fessler et al. CURRENT PHARMACEUTICAL DESIGN
- Specific Acetylation of p53 by HDAC Inhibition Prevents DNA Damage-Induced Apoptosis in Neurons
- (2013) C. Brochier et al. JOURNAL OF NEUROSCIENCE
- Disassociation of Histone Deacetylase-3 from Normal Huntingtin Underlies Mutant Huntingtin Neurotoxicity
- (2013) F. H. Bardai et al. JOURNAL OF NEUROSCIENCE
- Controversies and evolving new mechanisms in subarachnoid hemorrhage
- (2013) Sheng Chen et al. PROGRESS IN NEUROBIOLOGY
- Bim, a Proapoptotic Protein, Up-regulated via Transcription Factor E2F1-dependent Mechanism, Functions as a Prosurvival Molecule in Cancer
- (2012) Raghu Gogada et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- GCN5 acetylates and regulates the stability of the oncoprotein E2A-PBX1 in acute lymphoblastic leukemia
- (2012) T Holmlund et al. LEUKEMIA
- USP22 Antagonizes p53 Transcriptional Activation by Deubiquitinating Sirt1 to Suppress Cell Apoptosis and Is Required for Mouse Embryonic Development
- (2012) Zhenghong Lin et al. MOLECULAR CELL
- Tip60 HAT Activity Mediates APP Induced Lethality and Apoptotic Cell Death in the CNS of a Drosophila Alzheimer's Disease Model
- (2012) Sheila K. Pirooznia et al. PLoS One
- The importance of early brain injury after subarachnoid hemorrhage
- (2012) Fatima A. Sehba et al. PROGRESS IN NEUROBIOLOGY
- 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site
- (2011) Massimo Ghizzoni et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Egr-1 Transactivates Bim Gene Expression to Promote Neuronal Apoptosis
- (2011) B. Xie et al. JOURNAL OF NEUROSCIENCE
- Paradoxical Enhancement of Fear Extinction Memory and Synaptic Plasticity by Inhibition of the Histone Acetyltransferase p300
- (2011) R. Marek et al. JOURNAL OF NEUROSCIENCE
- -Synuclein Negatively Regulates Protein Kinase C Expression to Suppress Apoptosis in Dopaminergic Neurons by Reducing p300 Histone Acetyltransferase Activity
- (2011) H. Jin et al. JOURNAL OF NEUROSCIENCE
- NF-Y is essential for expression of the proapoptotic bim gene in sympathetic neurons
- (2010) R Hughes et al. CELL DEATH AND DIFFERENTIATION
- Virtual Ligand Screening of the p300/CBP Histone Acetyltransferase: Identification of a Selective Small Molecule Inhibitor
- (2010) Erin M. Bowers et al. CHEMISTRY & BIOLOGY
- Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation
- (2010) Qihuang Jin et al. EMBO JOURNAL
- Neuroprotection by Histone Deacetylase-7 (HDAC7) Occurs by Inhibition of c-junExpression through a Deacetylase-independent Mechanism
- (2010) Chi Ma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program
- (2010) D. Ren et al. SCIENCE
- The acetylation of RelA in Lys310 dictates the NF-κB-dependent response in post-ischemic injury
- (2010) A Lanzillotta et al. Cell Death & Disease
- Insights into SAGA function during gene expression
- (2009) Susana Rodríguez-Navarro EMBO REPORTS
- Opposing Roles for ATF2 and c-Fos in c-Jun-Mediated Neuronal Apoptosis
- (2009) Z. Yuan et al. MOLECULAR AND CELLULAR BIOLOGY
- Bim Upregulation by Histone Deacetylase Inhibitors Mediates Interactions with the Bcl-2 Antagonist ABT-737: Evidence for Distinct Roles for Bcl-2, Bcl-xL, and Mcl-1
- (2009) S. Chen et al. MOLECULAR AND CELLULAR BIOLOGY
- Gcn5 and SAGA Regulate Shelterin Protein Turnover and Telomere Maintenance
- (2009) Boyko S. Atanassov et al. MOLECULAR CELL
- HDAC6 is a target for protection and regeneration following injury in the nervous system
- (2009) M. A. Rivieccio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Multiple roles of HDAC inhibition in neurodegenerative conditions
- (2009) De-Maw Chuang et al. TRENDS IN NEUROSCIENCES
- A Novel Histone Acetyltransferase Inhibitor Modulating Gcn5 Network: Cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl)hydrazone
- (2008) Franco Chimenti et al. JOURNAL OF MEDICINAL CHEMISTRY
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