Respiratory syncytial virus disrupts the airway epithelial barrier by decreasing cortactin and destabilizing F-actin

Phosphoproteomic profiling of influenza virus entry reveals infection-triggered filopodia induction counteracted by dynamic cortactin phosphorylation

(2022) Annika Hunziker et al.   Cell Reports

RSV attenuates epithelial cell restitution by inhibiting actin cytoskeleton-dependent cell migration

(2021) Debra T Linfield et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The multifarious regulation of the apical junctional complex

(2020) Alexandra D. Rusu et al.   Open Biology

Titanium Dioxide Nanoparticles Exaggerate Respiratory Syncytial Virus-Induced Airway Epithelial Barrier Dysfunction

(2020) Carrie C Smallcombe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Host–Pathogen Responses to Pandemic Influenza H1N1pdm09 in a Human Respiratory Airway Model

(2020) Elizabeth A. Pharo et al.   Viruses-Basel

Epithelial barrier function properties of the 16HBE14o- human bronchial epithelial cell culture model

(2020) Patrick J. Callaghan et al.   BIOSCIENCE REPORTS

Improved binding of SARS-CoV-2 Envelope protein to tight junction-associated PALS1 could play a key role in COVID-19 pathogenesis

(2020) Flavio De Maio et al.   MICROBES AND INFECTION

Measles Virus Ribonucleoprotein Complexes Rapidly Spread across Well-Differentiated Primary Human Airway Epithelial Cells along F-Actin Rings

(2019) Brajesh K. Singh et al.   mBio

Cortactin: Cell Functions of A Multifaceted Actin-Binding Protein

(2018) Michael Schnoor et al.   TRENDS IN CELL BIOLOGY

The Many Faces of Rap1 GTPase

(2018) Anna Jaśkiewicz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Disruption of the airway epithelial barrier in a murine model of respiratory syncytial virus infection

(2018) Carrie C. Smallcombe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Visualizing the dynamic coupling of claudin strands to the actin cytoskeleton through ZO-1

(2017) Christina M. Van Itallie et al.   MOLECULAR BIOLOGY OF THE CELL

Cortactin deficiency causes increased RhoA/ROCK1-dependent actomyosin contractility, intestinal epithelial barrier dysfunction, and disproportionately severe DSS-induced colitis

(2017) A F Citalán-Madrid et al.   Mucosal Immunology

cAMP-dependent activation of protein kinase A attenuates respiratory syncytial virus-induced human airway epithelial barrier disruption

(2017) Fariba Rezaee et al.   PLoS One

Ongoing developments in RSV prophylaxis: a clinician’s analysis

(2017) Fariba Rezaee et al.   Current Opinion in Virology

Influenza virus damages the alveolar barrier by disrupting epithelial cell tight junctions

(2016) Kirsty R. Short et al.   EUROPEAN RESPIRATORY JOURNAL

Cortactin is a scaffolding platform for the E-cadherin adhesion complex and is regulated by protein kinase D1 phosphorylation

(2016) Robert Sroka et al.   JOURNAL OF CELL SCIENCE

Tight junctions: from simple barriers to multifunctional molecular gates

(2016) Ceniz Zihni et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Viral Bronchiolitis in Children

(2016) H. Cody Meissner   NEW ENGLAND JOURNAL OF MEDICINE

Persistent Morbillivirus Infection Leads to Altered Cortactin Distribution in Histiocytic Sarcoma Cells with Decreased Cellular Migration Capacity

(2016) Vanessa Maria Pfankuche et al.   PLoS One

Unravelling the Actin Cytoskeleton: A New Competitive Edge?

(2016) Andrew J. Davidson et al.   TRENDS IN CELL BIOLOGY

Caspase-mediated degradation of host cortactin that promotes influenza A virus infection in epithelial cells

(2016) Da-Yuan Chen et al.   VIROLOGY

Host cytoskeleton in respiratory syncytial virus assembly and budding

(2016) Shadi Shahriari et al.   Virology Journal

Loss of cortactin causes endothelial barrier dysfunction via disturbed adrenomedullin secretion and actomyosin contractility

(2016) Alexander García Ponce et al.   Scientific Reports

Long-Term Burden and Respiratory Effects of Respiratory Syncytial Virus Hospitalization in Preterm Infants—The SPRING Study

(2015) Xavier Carbonell-Estrany et al.   PLoS One

Breaking Barriers. New Insights into Airway Epithelial Barrier Function in Health and Disease

(2014) Fariba Rezaee et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Actin Dynamics, Architecture, and Mechanics in Cell Motility

(2014) Laurent Blanchoin et al.   PHYSIOLOGICAL REVIEWS

Effects of Human Parvovirus B19 and Bocavirus VP1 Unique Region on Tight Junction of Human Airway Epithelial A549 Cells

(2014) Chun-Ching Chiu et al.   PLoS One

Paramyxovirus Glycoprotein Incorporation, Assembly and Budding: A Three Way Dance for Infectious Particle Production

(2014) Farah El Najjar et al.   Viruses-Basel

Relative Respiratory Syncytial Virus Cytopathogenesis in Upper and Lower Respiratory Tract Epithelium

(2013) Hong Guo-Parke et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Binding to F-actin guides cadherin cluster assembly, stability, and movement

(2013) Soonjin Hong et al.   JOURNAL OF CELL BIOLOGY

Sustained Protein Kinase D Activation Mediates Respiratory Syncytial Virus-Induced Airway Barrier Disruption

(2013) F. Rezaee et al.   JOURNAL OF VIROLOGY

Respiratory Syncytial Virus-Associated Hospitalizations Among Children Less Than 24 Months of Age

(2013) C. B. Hall et al.   PEDIATRICS

Actin Stabilization by Jasplakinolide Affects the Function of Bone Marrow-Derived Late Endothelial Progenitor Cells

(2012) Xiaoyun Zhang et al.   PLoS One

Evidence for a causal relationship between respiratory syncytial virus infection and asthma

(2011) Pingsheng Wu et al.   Expert Review of Anti-Infective Therapy

Polyinosinic:polycytidylic acid induces protein kinase D–dependent disassembly of apical junctions and barrier dysfunction in airway epithelial cells

(2011) Fariba Rezaee et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cortactin deficiency is associated with reduced neutrophil recruitment but increased vascular permeability in vivo

(2011) Michael Schnoor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Subversion of the actin cytoskeleton during viral infection

(2011) Matthew P. Taylor et al.   NATURE REVIEWS MICROBIOLOGY

The SARS Coronavirus E Protein Interacts with PALS1 and Alters Tight Junction Formation and Epithelial Morphogenesis

(2010) Kim-Tat Teoh et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of actin cytoskeleton dynamics in cells

(2010) Sung Haeng Lee et al.   MOLECULES AND CELLS

Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life

(2010) N. Sigurs et al.   THORAX

Enhanced Rap1 Activation and Insulin Secretagogue Properties of an Acetoxymethyl Ester of an Epac-selective Cyclic AMP Analog in Rat INS-1 Cells

(2009) Oleg G. Chepurny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Burden of Respiratory Syncytial Virus Infection in Young Children

(2009) Caroline Breese Hall et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epac/Rap1 pathway regulates microvascular hyperpermeability induced by PAF in rat mesentery

(2008) R. H. Adamson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Rhinovirus Disrupts the Barrier Function of Polarized Airway Epithelial Cells

(2008) Umadevi Sajjan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

8-pCPT-2′-O-Me-cAMP-AM: An Improved Epac-Selective cAMP Analogue

(2008) Marjolein J. Vliem et al.   CHEMBIOCHEM

Cortactin branches out: Roles in regulating protrusive actin dynamics

(2008) Amanda Gatesman Ammer et al.   CELL MOTILITY AND THE CYTOSKELETON

Structural and functional associations of apical junctions with cytoskeleton

(2007) Jun Miyoshi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton

(2007) Andrea Hartsock et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES