Resistance evolution can disrupt antibiotic exposure protection through competitive exclusion of the protective species

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

(2022) Christopher JL Murray et al.   LANCET

Bacterial defenses against a natural antibiotic promote collateral resilience to clinical antibiotics

(2021) Lucas A. Meirelles et al.   PLOS BIOLOGY

Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection

(2021) Rachel Wheatley et al.   Nature Communications

Integrating fundamental processes to understand eco‐evolutionary community dynamics and patterns

(2021) Lynn Govaert et al.   FUNCTIONAL ECOLOGY

rpoS-mutation variants are selected in Pseudomonas aeruginosa biofilms under imipenem pressure

(2021) Xiangke Duan et al.   Cell and Bioscience

Bottleneck size and selection level reproducibly impact evolution of antibiotic resistance

(2021) Niels Mahrt et al.   Nature Ecology & Evolution

Inter-species interactions alter antibiotic efficacy in bacterial communities

(2021) Michael J. Bottery et al.   ISME Journal

Bacterial adaptation is constrained in complex communities

(2020) Thomas Scheuerl et al.   Nature Communications

Lung function and microbiota diversity in cystic fibrosis

(2020) Leah Cuthbertson et al.   Microbiome

Cross-feeding modulates the rate and mechanism of antibiotic resistance evolution in a model microbial community of Escherichia coli and Salmonella enterica

(2020) Elizabeth M. Adamowicz et al.   PLoS Pathogens

Ecology and evolution of antimicrobial resistance in bacterial communities

(2020) Michael J. Bottery et al.   ISME Journal

Optimization of nutritional and environmental conditions for pyocyanin production by urine isolates of Pseudomonas aeruginosa

(2020) Rehab Mohammed Elbargisy   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Clinical and microbiological characteristics of cystic fibrosis adults never colonized by Pseudomonas aeruginosa: Analysis of the French CF registry

(2019) Réchana Vongthilath et al.   PLoS One

Phenazine production promotes antibiotic tolerance and metabolic heterogeneity in Pseudomonas aeruginosa biofilms

(2019) Konstanze T. Schiessl et al.   Nature Communications

Pseudomonas aeruginosa inhibits Rhizopus microsporus germination through sequestration of free environmental iron

(2019) Courtney Kousser et al.   Scientific Reports

Influence of the lung microbiome on antibiotic susceptibility of cystic fibrosis pathogens

(2019) Eva Vandeplassche et al.   European Respiratory Review

Selection for antimicrobial resistance is reduced when embedded in a natural microbial community

(2019) Uli Klümper et al.   ISME Journal

Pyoverdine-Dependent Virulence of Pseudomonas aeruginosa Isolates From Cystic Fibrosis Patients

(2019) Donghoon Kang et al.   Frontiers in Microbiology

Coexistence with Pseudomonas aeruginosa alters Staphylococcus aureus transcriptome, antibiotic resistance and internalization into epithelial cells

(2019) Paul Briaud et al.   Scientific Reports

Universal antibiotic tolerance arising from antibiotic-triggered accumulation of pyocyanin in Pseudomonas aeruginosa

(2019) Kui Zhu et al.   PLOS BIOLOGY

Cross-feeding modulates antibiotic tolerance in bacterial communities

(2018) Elizabeth M. Adamowicz et al.   ISME Journal

Evolution of high-level resistance during low-level antibiotic exposure

(2018) Erik Wistrand-Yuen et al.   Nature Communications

Community interactions and spatial structure shape selection on antibiotic resistant lineages

(2018) Sylvie Estrela et al.   PLoS Computational Biology

Pyocyanin Restricts Social Cheating in Pseudomonas aeruginosa

(2018) Paulina Castañeda-Tamez et al.   Frontiers in Microbiology

Differential Regulation of the Phenazine Biosynthetic Operons by Quorum Sensing in Pseudomonas aeruginosa PAO1-N

(2018) Steven Higgins et al.   Frontiers in Cellular and Infection Microbiology

Collapse of genetic division of labour and evolution of autonomy in pellicle biofilms

(2018) Anna Dragoš et al.   Nature Microbiology

Stability and degradation products of imipenem applying High‐Resolution Mass Spectrometry: an analytical study focused on solutions for infusion

(2018) Fábio Souza Barbosa et al.   BIOMEDICAL CHROMATOGRAPHY

Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies

(2018) Zheng Pang et al.   BIOTECHNOLOGY ADVANCES

Pathological Mucus and Impaired Mucus Clearance in Cystic Fibrosis Patients Results from Increased Concentration, not altered pH

(2018) David B. Hill et al.   EUROPEAN RESPIRATORY JOURNAL

Co-evolution with Staphylococcus aureus leads to lipopolysaccharide alterations in Pseudomonas aeruginosa

(2017) Mikael Tognon et al.   ISME Journal

Development of carbapenem resistance in Pseudomonas aeruginosa is associated with OprD polymorphisms, particularly the amino acid substitution at codon 170

(2017) Jwu-Ching Shu et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Studies of Pseudomonas aeruginosa Mutants Indicate Pyoverdine as the Central Factor in Inhibition of Aspergillus fumigatus Biofilm

(2017) Gabriele Sass et al.   JOURNAL OF BACTERIOLOGY

Mechanisms of Pyocyanin Toxicity and Genetic Determinants of Resistance in Staphylococcus aureus

(2017) Michael J. Noto et al.   JOURNAL OF BACTERIOLOGY

Risk factors for and role of OprD protein in increasing minimal inhibitory concentrations of carbapenems in clinical isolates of Pseudomonas aeruginosa

(2017) Aki Hirabayashi et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Pseudomonas aeruginosa Alters Staphylococcus aureus Sensitivity to Vancomycin in a Biofilm Model of Cystic Fibrosis Infection

(2017) Giulia Orazi et al.   mBio

Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence

(2017) M. Fata Moradali et al.   Frontiers in Cellular and Infection Microbiology

Staphylococcus aureus interaction with Pseudomonas aeruginosa biofilm enhances tobramycin resistance

(2017) T. Beaudoin et al.   npj Biofilms and Microbiomes

Modulation of behaviour and virulence of a high alginate expressing Pseudomonas aeruginosa strain from cystic fibrosis by oral commensal bacterium Streptococcus anginosus

(2017) Richard D. Waite et al.   PLoS One

Overproduction of active efflux pump and variations of OprD dominate in imipenem-resistant Pseudomonas aeruginosa isolated from patients with bloodstream infections in Taiwan

(2016) Cheng-Yen Kao et al.   BMC MICROBIOLOGY

Inhaled Antibiotics for Gram-Negative Respiratory Infections

(2016) Eric Wenzler et al.   CLINICAL MICROBIOLOGY REVIEWS

Production of extended-spectrum β -lactamases and the potential indirect pathogenic role of Prevotella isolates from the cystic fibrosis respiratory microbiota

(2016) Laura J. Sherrard et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Causes of death in French cystic fibrosis patients: The need for improvement in transplantation referral strategies!

(2016) Clémence Martin et al.   Journal of Cystic Fibrosis

Risk factors for mortality in patients with Stenotrophomonas maltophilia bacteremia

(2016) Yong Duk Jeon et al.   MEDICINE

Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections

(2016) Craig Winstanley et al.   TRENDS IN MICROBIOLOGY

Collective Resistance in Microbial Communities by Intracellular Antibiotic Deactivation

(2016) Robin A. Sorg et al.   PLOS BIOLOGY

Coculture of Staphylococcus aureus with Pseudomonas aeruginosa Drives S. aureus towards Fermentative Metabolism and Reduced Viability in a Cystic Fibrosis Model

(2015) Laura M. Filkins et al.   JOURNAL OF BACTERIOLOGY

Emerging bacterial pathogens and changing concepts of bacterial pathogenesis in cystic fibrosis

(2015) Michael D. Parkins et al.   Journal of Cystic Fibrosis

Coevolution with Bacteriophages Drives Genome-Wide Host Evolution and Constrains the Acquisition of Abiotic-Beneficial Mutations

(2015) Pauline D. Scanlan et al.   MOLECULAR BIOLOGY AND EVOLUTION

Multifactorial Competition and Resistance in a Two-Species Bacterial System

(2015) Anupama Khare et al.   PLoS Genetics

Phenotypic Heterogeneity Affects Stenotrophomonas maltophilia K279a Colony Morphotypes and β-Lactamase Expression

(2015) Ebrahim M. Abda et al.   Frontiers in Microbiology

Prokka: rapid prokaryotic genome annotation

(2014) T. Seemann   BIOINFORMATICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

The evolving dynamics of the microbial community in the cystic fibrosis lung

(2014) Luke McGuigan et al.   ENVIRONMENTAL MICROBIOLOGY

Quorum sensing enhancement of the stress response promotes resistance to quorum quenching and prevents social cheating

(2014) Rodolfo García-Contreras et al.   ISME Journal

Antimicrobial resistance in the respiratory microbiota of people with cystic fibrosis

(2014) Laura J Sherrard et al.   LANCET

Pseudomonas aeruginosa eradicates Staphylococcus aureus by manipulating the host immunity

(2014) Erwan Pernet et al.   Nature Communications

Prevalence and detection of Stenotrophomonas maltophilia carrying metallo-β-lactamase blaL1 in Beijing, China

(2014) Zhan Yang et al.   Frontiers in Microbiology

Cystic Fibrosis Therapy: A Community Ecology Perspective

(2013) Douglas Conrad et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Interspecies signalling:Pseudomonas putidaefflux pump TtgGHI is activated by indole to increase antibiotic resistance

(2013) Carlos Molina-Santiago et al.   ENVIRONMENTAL MICROBIOLOGY

OprD mutations and inactivation in imipenem-resistant Pseudomonas aeruginosa isolates from China

(2013) Zhi-li Fang et al.   INFECTION GENETICS AND EVOLUTION

Complexity of resistance mechanisms to imipenem in intensive care unit strains of Pseudomonas aeruginosa

(2013) Damien Fournier et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antibiotic resistance—the need for global solutions

(2013) Ramanan Laxminarayan et al.   LANCET INFECTIOUS DISEASES

Phenotypic Heterogeneity of Pseudomonas aeruginosa Populations in a Cystic Fibrosis Patient

(2013) Matthew L. Workentine et al.   PLoS One

Direct observation of single stationary-phase bacteria reveals a surprisingly long period of constant protein production activity

(2013) O. Gefen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced in vivo fitness of carbapenem-resistant oprD mutants of Pseudomonas aeruginosa revealed through high-throughput sequencing

(2013) D. Skurnik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation

(2013) C. T. O'Loughlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alterations of OprD in Carbapenem-Intermediate and -Susceptible Strains of Pseudomonas aeruginosa Isolated from Patients with Bacteremia in a Spanish Multicenter Study

(2012) Alain A. Ocampo-Sosa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Pyoverdine biosynthesis and secretion inPseudomonas aeruginosa: implications for metal homeostasis

(2012) Isabelle J. Schalk et al.   ENVIRONMENTAL MICROBIOLOGY

Structure and function of OprD protein in Pseudomonas aeruginosa: From antibiotic resistance to novel therapies

(2012) Hui Li et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing

(2012) Anton Bankevich et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Decade-long bacterial community dynamics in cystic fibrosis airways

(2012) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mucin Promotes Rapid Surface Motility in Pseudomonas aeruginosa

(2012) A. T. Y. Yeung et al.   mBio

Use of Artificial Sputum Medium to Test Antibiotic Efficacy Against Pseudomonas aeruginosa in Conditions More Relevant to the Cystic Fibrosis Lung

(2012) Sebastian Kirchner et al.   Jove-Journal of Visualized Experiments

Pseudomonas siderophores in the sputum of patients with cystic fibrosis

(2011) Lois W. Martin et al.   BIOMETALS

Metabolite-based mutualism between Pseudomonas aeruginosa PA14 and Enterobacter aerogenes enhances current generation in bioelectrochemical systems

(2011) Arvind Venkataraman et al.   Energy & Environmental Science

The Stringent Response Is Essential for Pseudomonas aeruginosa Virulence in the Rat Lung Agar Bead and Drosophila melanogaster Feeding Models of Infection

(2011) Stefanie L. Vogt et al.   INFECTION AND IMMUNITY

Chronic pulmonary infection with Stenotrophomonas maltophilia and lung function in patients with cystic fibrosis

(2011) C.S. Dalbøge et al.   Journal of Cystic Fibrosis

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Cystic Fibrosis Pulmonary Guidelines

(2010) Patrick A. Flume et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Parasitic growth of Pseudomonas aeruginosa in co-culture with the chitinolytic bacterium Aeromonas hydrophila

(2010) Nina Jagmann et al.   ENVIRONMENTAL MICROBIOLOGY

Pseudomonas aeruginosa Exotoxin Pyocyanin Causes Cystic Fibrosis Airway Pathogenesis

(2009) Charles C. Caldwell et al.   AMERICAN JOURNAL OF PATHOLOGY

Protection of Salmonella by ampicillin-resistant Escherichia coli in the presence of otherwise lethal drug concentrations

(2009) M. H. Perlin et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Induction of L1 and L2  -Lactamase Production in Stenotrophomonas maltophilia Is Dependent on an AmpR-Type Regulator

(2008) A. Okazaki et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nebulized imipenem to control nosocomial pneumonia caused by Pseudomonas aeruginosa

(2008) M. Radhakrishnan et al.   JOURNAL OF CRITICAL CARE

Interspecies signalling via the Stenotrophomonas maltophilia diffusible signal factor influences biofilm formation and polymyxin tolerance in Pseudomonas aeruginosa

(2008) Robert P. Ryan et al.   MOLECULAR MICROBIOLOGY

Purification and characterization of an antimicrobial peptide produced by Pseudomonas sp. strain 4B

(2008) Roberta Fontoura et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY