Cucumber-Derived Nanovesicles Containing Cucurbitacin B for Non-Small Cell Lung Cancer Therapy

Targeting cancer stem cells with a pan-BCL-2 inhibitor in preclinical and clinical settings in patients with gastroesophageal carcinoma

(2021) Shumei Song et al.   GUT

STAT3 promotes peritoneal metastasis of gastric cancer by enhancing mesothelial-mesenchymal transition

(2021) Hongkui Yang et al.   BIOLOGICAL CHEMISTRY

Engineering Exosome-Like Nanovesicles Derived from Asparagus cochinchinensis Can Inhibit the Proliferation of Hepatocellular Carcinoma Cells with Better Safety Profile

(2021) Lei Zhang et al.   International Journal of Nanomedicine

Delivery of functional exogenous proteins by plant-derived vesicles to human cells in vitro

(2021) Luiza Garaeva et al.   Scientific Reports

Chitosan oligosaccharide decorated liposomes combined with TH302 for photodynamic therapy in triple negative breast cancer

(2021) Yinan Ding et al.   JOURNAL OF NANOBIOTECHNOLOGY

Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway

(2021) Charles L. Evavold et al.   CELL

Are sugar-sweetened beverages contributing to the rising occurrence of colorectal cancer in young adults?

(2021) Neil Murphy et al.   GUT

Cucurbitacin B inhibits non-small cell lung cancer in vivo and in vitro by triggering TLR4/NLRP3/GSDMD-dependent pyroptosis

(2021) Renyikun Yuan et al.   PHARMACOLOGICAL RESEARCH

NIR‐II Excitation Phototheranostic Nanomedicine for Fluorescence/Photoacoustic Tumor Imaging and Targeted Photothermal‐Photonic Thermodynamic Therapy

(2021) Yeneng Dai et al.   Small

The Antioxidant Effect of Small Extracellular Vesicles Derived from Aloe vera Peels for Wound Healing

(2021) Min Kang Kim et al.   Tissue Engineering and Regenerative Medicine

A dual-modal aptasensor based on a multifunctional acridone derivate for exosomes detection

(2021) Yaokun Xia et al.   ANALYTICA CHIMICA ACTA

A multifunctional nanoamplifier with self-enhanced acidity and hypoxia relief for combined photothermal/photodynamic/starvation therapy

(2021) Shanshan Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Isolation of cabbage exosome-like nanovesicles and investigation of their biological activities in human cells

(2021) Jae Young You et al.   Bioactive Materials

A folic acid-modified non-viral vector combines gene therapy with chemotherapy to reverse cancer chemotherapy resistance

(2021) Jing Chen et al.   Applied Materials Today

The Global Macroeconomic Burden of Breast Cancer

(2020) Kavitha Ranganathan et al.   ANNALS OF SURGERY

Cucurbitacin B inhibits gastric cancer progression by suppressing STAT3 activity

(2020) Jiaxin Xu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

STAT3 Regulates Mouse Neural Progenitor Proliferation and Differentiation by Promoting Mitochondrial Metabolism

(2020) Yixun Su et al.   Frontiers in Cell and Developmental Biology

Encapsulation of cucurbitacin B into lipid polymer hybrid nanocarriers induced apoptosis of MDAMB231 cells through PARP cleavage

(2020) Filiz Bakar-Ates et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

An efficient method to isolate lemon derived extracellular vesicles for gastric cancer therapy

(2020) Meng Yang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Plant-Derived Nanovesicles: A Novel Form of Nanomedicine

(2020) Lanlan Yu et al.   Frontiers in Bioengineering and Biotechnology

Plant Exosome-like Nanovesicles: Emerging Therapeutics and Drug Delivery Nanoplatforms

(2020) Haseeb Anwar Dad et al.   MOLECULAR THERAPY

A Compressive Review about Taxol®: History and Future Challenges

(2020) Julia Gallego-Jara et al.   MOLECULES

Polymers and inorganic nanoparticles: A winning combination towards assembled nanostructures for cancer imaging and therapy

(2020) Kuikun Yang et al.   Nano Today

Extracellular Vesicles from Fresh and Dried Plants—Simultaneous Purification and Visualization Using Gel Electrophoresis

(2019) Eric Woith et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Plant Extracellular Vesicles Contain Diverse Small RNA Species and Are Enriched in 10- to 17-Nucleotide “Tiny” RNAs

(2019) Patricia Baldrich et al.   PLANT CELL

Cucurbitacin B induces inhibitory effects via the CIP2A/PP2A/C-KIT signaling axis in t(8;21) acute myeloid leukemia

(2019) Wenjing Ma et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

STAT3 controls osteoclast differentiation and bone homeostasis by regulating NFATc1 transcription

(2019) Yiling Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Repurposing of drugs as STAT3 inhibitors for cancer therapy

(2019) Pathum S. Thilakasiri et al.   SEMINARS IN CANCER BIOLOGY

Responsive Exosome Nano-bioconjugates for Synergistic Cancer Therapy

(2019) Weidong Nie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modified mixed nanomicelles with collagen peptides enhanced oral absorption of Cucurbitacin B: preparation and evaluation

(2018) Lan Tang et al.   DRUG DELIVERY

Mixed-Charged Zwitterionic Polymeric Micelles for Tumor Acidic Environment Responsive Intracellular Drug Delivery

(2018) Zhihui Qin et al.   LANGMUIR

Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes

(2018) Qiang Cai et al.   SCIENCE

ROS signalling in the biology of cancer

(2018) Jennifer N. Moloney et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Antitumor activity of nimotuzumab in combination with cisplatin in lung cancer cell line A549 in�vitro

(2018) Yanhong Yang et al.   Oncology Letters

Dual-stimuli-responsive TiOx/DOX nanodrug system for lung cancer synergistic therapy

(2018) Zideng Dai et al.   RSC Advances

Bone metastasis target redox-responsive micell for the treatment of lung cancer bone metastasis and anti-bone resorption

(2018) Wei-Liang Ye et al.   Artificial Cells Nanomedicine and Biotechnology

Arrowtail RNA for Ligand Display on Ginger Exosome-like Nanovesicles to Systemic Deliver siRNA for Cancer Suppression

(2018) Zhefeng Li et al.   Scientific Reports

Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota

(2018) Yun Teng et al.   Cell Host & Microbe

Evaluation of Cytotoxic Potentials of Some Isoindole-1,3-Dione Derivatives on HeLa, C6 and A549 Cancer Cell Lines

(2018) Ayse Tan et al.   Medicinal Chemistry

Cucurbitacin B Induces Hypermethylation of Oncogenes in Breast Cancer Cells

(2018) Kanthanadon Dittharot et al.   PLANTA MEDICA

Dual functions of STAT3 in LPS-induced angiogenesis of hepatocellular carcinoma

(2018) Zhuo Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cucurbitacin B synergistically enhances the apoptosis-inducing effect of arsenic trioxide by inhibiting STAT3 phosphorylation in lymphoma Ramos cells

(2017) Xiuli Ding et al.   LEUKEMIA & LYMPHOMA

Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer

(2016) Mingzhen Zhang et al.   BIOMATERIALS

Edible Ginger-derived Nano-lipids Loaded with Doxorubicin as a Novel Drug-delivery Approach for Colon Cancer Therapy

(2016) Mingzhen Zhang et al.   MOLECULAR THERAPY

Synergistic effect of cucurbitacin B in combination with curcumin via enhancing apoptosis induction and reversing multidrug resistance in human hepatoma cells

(2015) Yuqi Sun et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells

(2015) Jin Mo Ku et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung cancer cells

(2014) MENG ZHANG et al.   Molecular Medicine Reports

Grape Exosome-like Nanoparticles Induce Intestinal Stem Cells and Protect Mice From DSS-Induced Colitis

(2013) Songwen Ju et al.   MOLECULAR THERAPY

Delivery of therapeutic agents by nanoparticles made of grapefruit-derived lipids

(2013) Qilong Wang et al.   Nature Communications

Intratumoral injection of taxol in vivo suppresses A549 tumor showing cytoplasmic vacuolization

(2011) Chaoyang Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Vesicular fractions of sunflower apoplastic fluids are associated with potential exosome marker proteins

(2009) Mariana Regente et al.   FEBS LETTERS

Interaction of cucurbitacins with human serum albumin: Thermodynamic characteristics and influence on the binding of site specific ligands

(2009) Rony Abou-Khalil et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY