Pharmacological and In Silico Analysis of Oat Avenanthramides as EGFR Inhibitors: Effects on EGF-Induced Lung Cancer Cell Growth and Migration

Avenanthramide C induces cellular senescence in colorectal cancer cells via suppressing β-catenin-mediated the transcription of miR-183/96/182 cluster

(2022) Rong Fu et al.   BIOCHEMICAL PHARMACOLOGY

Oat polyphenol avenanthramide-2c confers protection from oxidative stress by regulating the Nrf2-ARE signaling pathway in PC12 cells

(2021) Yanan Hou et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Epidermal Growth Factor Receptor Expression and Resistance Patterns to Targeted Therapy in Non-Small Cell Lung Cancer: A Review

(2021) Emma-Anne Karlsen et al.   Cells

Multiple Antioxidative and Bioactive Molecules of Oats (Avena sativa L.) in Human Health

(2021) Il-Sup Kim et al.   Antioxidants

A review on epidermal growth factor receptor's role in breast and non-small cell lung cancer

(2021) Vetriselvan Subramaniyan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

ProLIF: a library to encode molecular interactions as fingerprints

(2021) Cédric Bouysset et al.   Journal of Cheminformatics

Avenanthramide C suppresses hypoxia-induced cyclooxygenase-2 expression through sirtuin1 activation in non-small-cell lung cancer cells

(2020) Wonchung Lim et al.   Animal Cells and Systems

How ATP-Competitive Inhibitors Allosterically Modulate Tyrosine Kinases That Contain a Src-like Regulatory Architecture

(2020) Linglan Fang et al.   ACS Chemical Biology

PyMod 3: a complete suite for structural bioinformatics in PyMOL

(2020) Giacomo Janson et al.   BIOINFORMATICS

Prostaglandin E2 and Cancer: Insight into Tumor Progression and Immunity

(2020) Federica Finetti et al.   Biology-Basel

Cytoprotective effects of Avenathramide C against oxidative and inflammatory stress in normal human dermal fibroblasts

(2019) Chenxuan Wang et al.   Scientific Reports

Avenanthramide A induces cellular senescence via miR-129-3p/Pirh2/p53 signaling pathway to suppress colon cancer growth

(2019) Rong Fu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Identification of 2(1H)-Pyrimidinones as Potential EGFR T790M Inhibitors for the Treatment of Gefitinib-resistant Non-small Cell Lung Cancer

(2019) Jianping Huang et al.   BIOORGANIC CHEMISTRY

Overview of the Anticancer Profile of Avenanthramides from Oat

(2019) Eleonora Turrini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Avenanthramide A triggers potent ROS-mediated anti-tumor effects in colorectal cancer by directly targeting DDX3

(2019) Rong Fu et al.   Cell Death & Disease

High Levels of Avenanthramides in Oat-Based Diet Further Suppress High Fat Diet-Induced Atherosclerosis in Ldlr–/– Mice

(2018) Michael Thomas et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Biological Activities, Health Benefits, and Therapeutic Properties of Avenanthramides: From Skin Protection to Prevention and Treatment of Cerebrovascular Diseases

(2018) Andrea Perrelli et al.   Oxidative Medicine and Cellular Longevity

Yeast-Derived Recombinant Avenanthramides Inhibit Proliferation, Migration and Epithelial Mesenchymal Transition of Colon Cancer Cells

(2018) Federica Finetti et al.   Nutrients

Cyclooxygenase-2 in cancer: A review

(2018) Nasser Hashemi Goradel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

PubChem 2019 update: improved access to chemical data

(2018) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

Mechanism of Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors and a Potential Treatment Strategy

(2018) Tatsuya Nagano et al.   Cells

Antiproliferative activity of vitexin-2-O-xyloside and avenanthramides on CaCo-2 and HepG2 cancer cells occurs through apoptosis induction and reduction of pro-survival mechanisms

(2017) Emanuele Salvatore Scarpa et al.   EUROPEAN JOURNAL OF NUTRITION

AutoDock VinaXB: implementation of XBSF, new empirical halogen bond scoring function, into AutoDock Vina

(2016) Mathew R. Koebel et al.   Journal of Cheminformatics

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

(2016) Linda S. Steelman et al.   Aging-US

Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast

(2015) Andrea Moglia et al.   BIOFACTORS

PLIP: fully automated protein–ligand interaction profiler

(2015) Sebastian Salentin et al.   NUCLEIC ACIDS RESEARCH

UniProt: a hub for protein information

(2014)   NUCLEIC ACIDS RESEARCH

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

(2013) Jing Huang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

αC helix displacement as a general approach for allosteric modulation of protein kinases

(2012) Lorenzo Palmieri et al.   DRUG DISCOVERY TODAY

Pharmacological Inhibition of Microsomal Prostaglandin E Synthase-1 Suppresses Epidermal Growth Factor Receptor-Mediated Tumor Growth and Angiogenesis

(2012) Federica Finetti et al.   PLoS One

Dihydroavenanthramide D inhibits human breast cancer cell invasion through suppression of MMP-9 expression

(2011) Young-Rae Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Open Babel: An open chemical toolbox

(2011) Noel M O'Boyle et al.   Journal of Cheminformatics

Avenanthramides Inhibit Proliferation of Human Colon Cancer Cell Lines In Vitro

(2010) Weimin Guo et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Potential health benefits of avenanthramides of oats

(2009) Mohsen Meydani   NUTRITION REVIEWS