Genetic tracing reveals transcription factor Foxp3-dependent and Foxp3-independent functionality of peripherally induced Treg cells

Regulatory T cells function in established systemic inflammation and reverse fatal autoimmunity

(2021) Wei Hu et al.   NATURE IMMUNOLOGY

Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity

(2021) Alexandra Schnell et al.   CELL

Local immune response as novel disease mechanism underlying abdominal pain in patients with irritable bowel syndrome

(2021) J. Aguilera-Lizarraga et al.   ACTA CLINICA BELGICA

Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells

(2020) Clarissa Campbell et al.   NATURE

Scirpy: a Scanpy extension for analyzing single-cell T-cell receptor-sequencing data

(2020) Gregor Sturm et al.   BIOINFORMATICS

c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis

(2019) Christian Neumann et al.   NATURE IMMUNOLOGY

The Intestine Harbors Functionally Distinct Homeostatic Tissue-Resident and Inflammatory Th17 Cells

(2019) Sara Omenetti et al.   IMMUNITY

IL-2 production by self-reactive CD4 thymocytes scales regulatory T cell generation in the thymus

(2019) Saskia Hemmers et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functional reprogramming of regulatory T cells in the absence of Foxp3

(2019) Louis-Marie Charbonnier et al.   NATURE IMMUNOLOGY

Developmental and cellular age direct conversion of CD4+ T cells into RORγ+ or Helios+ colon Treg cells

(2019) Alvin Pratama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bile acid metabolites control TH17 and Treg cell differentiation

(2019) Saiyu Hang et al.   NATURE

Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis

(2019) Xinyang Song et al.   NATURE

Recovering Gene Interactions from Single-Cell Data Using Data Diffusion

(2018) David van Dijk et al.   CELL

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

(2018) Elham Azizi et al.   CELL

Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance

(2018) Clarissa Campbell et al.   IMMUNITY

c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont

(2018) Mo Xu et al.   NATURE

Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+and Follicular Phenotypes

(2017) Joshua D. Wheaton et al.   JOURNAL OF IMMUNOLOGY

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Generation of RORγt + Antigen-Specific T Regulatory 17 Cells from Foxp3 + Precursors in Autoimmunity

(2017) Byung-Seok Kim et al.   Cell Reports

Dietary antigens limit mucosal immunity by inducing regulatory T cells in the small intestine

(2016) K. S. Kim et al.   SCIENCE

Rapid and Efficient Generation of Regulatory T Cells to Commensal Antigens in the Periphery

(2016) Katherine Nutsch et al.   Cell Reports

Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity

(2015) Jellert T. Gaublomme et al.   CELL

Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis

(2015) Jacob H. Levine et al.   CELL

The microbiota regulates type 2 immunity through ROR t+ T cells

(2015) C. Ohnmacht et al.   SCIENCE

Individual intestinal symbionts induce a distinct population of ROR + regulatory T cells

(2015) E. Sefik et al.   SCIENCE

Differences in Expression Level of Helios and Neuropilin-1 Do Not Distinguish Thymus-Derived from Extrathymically-Induced CD4+Foxp3+ Regulatory T Cells

(2015) Edyta Szurek et al.   PLoS One

Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells

(2014) Aaron Arvey et al.   NATURE IMMUNOLOGY

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

TGF-β Signalling Is Required for CD4+ T Cell Homeostasis But Dispensable for Regulatory T Cell Function

(2013) Anna Śledzińska et al.   PLOS BIOLOGY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+T reg cells

(2012) Jonathan M. Weiss et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo

(2012) Mahesh Yadav et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Induction and molecular signature of pathogenic TH17 cells

(2012) Youjin Lee et al.   NATURE IMMUNOLOGY

Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells

(2011) R. A. Gottschalk et al.   JOURNAL OF IMMUNOLOGY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

(2010) A. M. Thornton et al.   JOURNAL OF IMMUNOLOGY

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

(2010) Ye Zheng et al.   NATURE

Natural and Adaptive Foxp3+ Regulatory T Cells: More of the Same or a Division of Labor?

(2009) Maria A. Curotto de Lafaille et al.   IMMUNITY

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire

(2008) Matthew A. Burchill et al.   IMMUNITY

A Two-Step Process for Thymic Regulatory T Cell Development

(2008) Chan-Wang Joaquim Lio et al.   IMMUNITY

Differentiation of regulatory Foxp3+ T cells in the thymic cortex

(2008) A. Liston et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA