Metabolic transitions define spermatogonial stem cell maturation

Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment

(2021) Jingtao Guo et al.   Cell Stem Cell

Specification and epigenomic resetting of the pig germline exhibit conservation with the human lineage

(2021) Qifan Zhu et al.   Cell Reports

Unique metabolic phenotype and its transition during maturation of juvenile male germ cells

(2021) Anna Laura Voigt et al.   FASEB JOURNAL

Metabolo-epigenetics: the interplay of metabolism and epigenetics during early germ cells development†

(2021) Roxane Verdikt et al.   BIOLOGY OF REPRODUCTION

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty

(2020) Jingtao Guo et al.   Cell Stem Cell

Metabolic Changes Accompanying Spermatogonial Stem Cell Differentiation

(2020) Tessa Lord et al.   DEVELOPMENTAL CELL

Single-Cell RNA Sequencing of Human, Macaque, and Mouse Testes Uncovers Conserved and Divergent Features of Mammalian Spermatogenesis

(2020) Adrienne Niederriter Shami et al.   DEVELOPMENTAL CELL

The Neonatal and Adult Human Testis Defined at the Single-Cell Level

(2019) Abhishek Sohni et al.   Cell Reports

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Aging of spermatogonial stem cells by Jnk-mediated glycolysis activation

(2019) Mito Kanatsu-Shinohara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular regulation of spermatogonial stem cell renewal and differentiation

(2019) Juho-Antti Mäkelä et al.   REPRODUCTION

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos

(2018) Vasileios I. Floros et al.   NATURE CELL BIOLOGY

Metabolic regulation of pluripotency and germ cell fate through α‐ketoglutarate

(2018) Julia Tischler et al.   EMBO JOURNAL

The adult human testis transcriptional cell atlas

(2018) Jingtao Guo et al.   CELL RESEARCH

Alpha‐ketoglutarate: a “magic” metabolite in early germ cell development

(2018) Vivian Lu et al.   EMBO JOURNAL

The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to Spermatids

(2018) Brian P. Hermann et al.   Cell Reports

Distinct requirements for energy metabolism in mouse primordial germ cells and their reprogramming to embryonic germ cells

(2017) Yohei Hayashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-Term Propagation of Porcine Undifferentiated Spermatogonia

(2017) Pengfei Zhang et al.   STEM CELLS AND DEVELOPMENT

Glycolysis-Optimized Conditions Enhance Maintenance of Regenerative Integrity in Mouse Spermatogonial Stem Cells during Long-Term Culture

(2017) Aileen R. Helsel et al.   Stem Cell Reports

Conditions for Long-Term Culture of Cattle Undifferentiated Spermatogonia

(2016) M. J. Oatley et al.   BIOLOGY OF REPRODUCTION

mTORC1 Activation Promotes Spermatogonial Differentiation and Causes Subfertility in Mice

(2016) C. Wang et al.   BIOLOGY OF REPRODUCTION

Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification

(2016) Ferdinand von Meyenn et al.   DEVELOPMENTAL CELL

Myc/Mycn-mediated glycolysis enhances mouse spermatogonial stem cell self-renewal

(2016) Mito Kanatsu-Shinohara et al.   GENES & DEVELOPMENT

The Sertoli cell: one hundred fifty years of beauty and plasticity

(2016) L. R. França et al.   Andrology

Glial cell line-derived neurotrophic factor in combination with insulin-like growth factor 1 and basic fibroblast growth factor promotein vitroculture of goat spermatogonial stem cells

(2015) M. Bahadorani et al.   GROWTH FACTORS

mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy

(2015) Jinghui Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IGF-1R Signaling Is Essential for the Proliferation of Cultured Mouse Spermatogonial Stem Cells by Promoting the G2/M Progression of the Cell Cycle

(2015) Si Wang et al.   STEM CELLS AND DEVELOPMENT

Functional and molecular features of the Id4+ germline stem cell population in mouse testes

(2014) F. Chan et al.   GENES & DEVELOPMENT

BoxPlotR: a web tool for generation of box plots

(2014) Michaela Spitzer et al.   NATURE METHODS

Serine, but Not Glycine, Supports One-Carbon Metabolism and Proliferation of Cancer Cells

(2014) Christiaan F. Labuschagne et al.   Cell Reports

Gonocytes, from the Fifties to the Present: Is There a Reason to Change the Name?1

(2013) Martine Culty   BIOLOGY OF REPRODUCTION

Insulin/IGF-1 Signaling Regulates Proteasome Activity through the Deubiquitinating Enzyme UBH-4

(2013) Olli Matilainen et al.   Cell Reports

Expression of the Ubiquitin Proteasome System in Neonatal Rat Gonocytes and Spermatogonia: Role in Gonocyte Differentiation1

(2012) Gurpreet Manku et al.   BIOLOGY OF REPRODUCTION

The Germline Stem Cell Niche Unit in Mammalian Testes

(2012) Jon M. Oatley et al.   PHYSIOLOGICAL REVIEWS

Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis

(2012) M. Raverdeau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Spermatogonial morphology and kinetics during testis development in mice: a high-resolution light microscopy approach

(2011) Ana Luiza Drumond et al.   REPRODUCTION

Plzf Regulates Germline Progenitor Self-Renewal by Opposing mTORC1

(2010) Robin M. Hobbs et al.   CELL

In VivoResidue-specific Histone Methylation Dynamics

(2009) Barry M. Zee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Propagation of bovine spermatogonial stem cells in vitro

(2008) Pedro M Aponte et al.   REPRODUCTION