Comparative Hepatotoxicity of a Novel Perfluoroalkyl Ether Sulfonic Acid, Nafion Byproduct 2 (H-PFMO2OSA), and Legacy Perfluorooctane Sulfonate (PFOS) in Adult Male Mice

Per-/polyfluoroalkyl substance concentrations in human serum and their associations with liver cancer

(2022) Linping Cao et al.   CHEMOSPHERE

Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?

(2021) Styliani Fragki et al.   CRITICAL REVIEWS IN TOXICOLOGY

Perfluorononanoic acid impedes mouse oocyte maturation by inducing mitochondrial dysfunction and oxidative stress

(2021) Xiaofei Jiao et al.   REPRODUCTIVE TOXICOLOGY

Developmental toxicity of Nafion byproduct 2 (NBP2) in the Sprague-Dawley rat with comparisons to hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) and perfluorooctane sulfonate (PFOS)

(2021) Justin M. Conley et al.   ENVIRONMENT INTERNATIONAL

Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxatilis) are associated with biomarkers of altered immune and liver function

(2020) T.C. Guillette et al.   ENVIRONMENT INTERNATIONAL

Legacy and emerging per- and polyfluoroalkyl substances (PFASs) in the coastal environment of Korea: Occurrence, spatial distribution, and bioaccumulation potential

(2020) Jae-Won Lee et al.   CHEMOSPHERE

Novel Perfluoroalkyl Ether Carboxylic Acids (PFECAs) and Sulfonic Acids (PFESAs): Occurrence and Association with Serum Biochemical Parameters in Residents Living Near a Fluorochemical Plant in China

(2020) Jingzhi Yao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Legacy and Novel Per- and Polyfluoroalkyl Substances in Juvenile Seabirds from the U.S. Atlantic Coast

(2020) Anna R. Robuck et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Perfluorooctane sulfonate (PFOS) disrupts testosterone biosynthesis via CREB/CRTC2/StAR signaling pathway in Leydig cells

(2020) Lianglin Qiu et al.   TOXICOLOGY

Environmental perfluoroalkyl acid exposures are associated with liver disease characterized by apoptosis and altered serum adipocytokines

(2019) John Bassler et al.   ENVIRONMENTAL POLLUTION

Hepatic metabolic adaptation in a murine model of glutathione deficiency

(2019) Ying Chen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Liver function biomarkers disorder is associated with exposure to perfluoroalkyl acids in adults: Isomers of C8 Health Project in China

(2019) Min Nian et al.   ENVIRONMENTAL RESEARCH

Oxidative stress biomarkers in the serum and plasma of patients with non-alcoholic fatty liver disease (NAFLD). Can plasma AGE be a marker of NAFLD? Oxidative stress biomarkers in NAFLD patients

(2019) Magdalena Świderska et al.   FREE RADICAL RESEARCH

Perfluoroalkyl substances and severity of nonalcoholic fatty liver in Children: An untargeted metabolomics approach

(2019) Ran Jin et al.   ENVIRONMENT INTERNATIONAL

Perfluorooctane sulphonate induces oxidative hepatic damage via mitochondria-dependent and NF-κB/TNF-α-mediated pathway

(2018) Rui Han et al.   CHEMOSPHERE

Molecular actions of PPARα in lipid metabolism and inflammation

(2018) Nadia Bougarne et al.   ENDOCRINE REVIEWS

Chlorinated Polyfluorinated Ether Sulfonates Exhibit Higher Activity toward Peroxisome Proliferator-Activated Receptors Signaling Pathways than Perfluorooctanesulfonate

(2018) Chuan-Hai Li et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The glutathione cycle: Glutathione metabolism beyond the γ-glutamyl cycle

(2018) Anand Kumar Bachhawat et al.   IUBMB LIFE

Subchronic Hepatotoxicity Effects of 6:2 Chlorinated Polyfluorinated Ether Sulfonate (6:2 Cl-PFESA), a Novel Perfluorooctane Sulfonate (PFOS) Alternative, on Adult Male Mice

(2018) Hongxia Zhang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

A Never-Ending Story of Per- and Polyfluoroalkyl Substances (PFASs)?

(2017) Zhanyun Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex

(2017) Suzanne N. Shapira et al.   GENES & DEVELOPMENT

Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice

(2017) Raymond E. Soccio et al.   JOURNAL OF CLINICAL INVESTIGATION

Half-lives of PFOS, PFHxS and PFOA after end of exposure to contaminated drinking water

(2017) Ying Li et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Comparative hepatotoxicity of 6:2 fluorotelomer carboxylic acid and 6:2 fluorotelomer sulfonic acid, two fluorinated alternatives to long-chain perfluoroalkyl acids, on adult male mice

(2016) Nan Sheng et al.   ARCHIVES OF TOXICOLOGY

Toxicity assessment of perfluorooctane sulfonate using acute and subchronic male C57BL/6J mouse models

(2016) Jiali Xing et al.   ENVIRONMENTAL POLLUTION

Unique cistrome defined as CsMBE is strictly required for Nrf2-sMaf heterodimer function in cytoprotection

(2016) Akihito Otsuki et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism

(2016) Akira Uruno et al.   MOLECULAR AND CELLULAR BIOLOGY

PFOS induces adipogenesis and glucose uptake in association with activation of Nrf2 signaling pathway

(2016) Jialin Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Chronic Glutathione Depletion Confers Protection against Alcohol-induced Steatosis: Implication for Redox Activation of AMP-activated Protein Kinase Pathway

(2016) Ying Chen et al.   Scientific Reports

Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo

(2015) Raymond E. Soccio et al.   CELL

Associations of perfluorinated chemical serum concentrations and biomarkers of liver function and uric acid in the US population (NHANES), 2007–2010

(2015) Jessie A. Gleason et al.   ENVIRONMENTAL RESEARCH

Identification of Novel Perfluoroalkyl Ether Carboxylic Acids (PFECAs) and Sulfonic Acids (PFESAs) in Natural Waters Using Accurate Mass Time-of-Flight Mass Spectrometry (TOFMS)

(2015) Mark Strynar et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Perfluoroalkyl acids and the isomers of perfluorooctanesulfonate and perfluorooctanoate in the sera of 50 new couples in Tianjin, China

(2014) Yifeng Zhang et al.   ENVIRONMENT INTERNATIONAL

Proteomic Analysis of Mouse Testis Reveals Perfluorooctanoic Acid-Induced Reproductive Dysfunction via Direct Disturbance of Testicular Steroidogenic Machinery

(2014) Hongxia Zhang et al.   JOURNAL OF PROTEOME RESEARCH

PFOS induced lipid metabolism disturbances in BALB/c mice through inhibition of low density lipoproteins excretion

(2014) Ling Wang et al.   Scientific Reports

Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements

(2014) Tsuyoshi Inoue et al.   GENOME BIOLOGY

PFOS-induced hepatic steatosis, the mechanistic actions on β-oxidation and lipid transport

(2012) H.T. Wan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glutathione synthesis

(2012) Shelly C. Lu   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Serum Perfluorooctanoate (PFOA) and Perfluorooctane Sulfonate (PFOS) Concentrations and Liver Function Biomarkers in a Population with Elevated PFOA Exposure

(2012) Valentina Gallo et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Association of Perfluorooctanoic Acid with HDL Cholesterol and Circulating miR-26b and miR-199–3p in Workers of a Fluorochemical Plant and Nearby Residents

(2012) Jianshe Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Mechanism of perfluorooctanesulfonate (PFOS)-induced apoptosis in the immunocyte

(2012) Ying-Hua Zhang et al.   Journal of Immunotoxicology

Effects of Perfluorinated Fatty Acids with Different Carbon Chain Length on Fatty Acid Profiles of Hepatic Lipids in Mice

(2011) Naomi Kudo et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Glutathione-Deficient Mice Are Susceptible to TCDD-Induced Hepatocellular Toxicity but Resistant to Steatosis

(2011) Ying Chen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Central role of mitochondria in drug-induced liver injury

(2011) Dominique Pessayre et al.   DRUG METABOLISM REVIEWS

Glucose and lipid homeostasis in adult rat is impaired by early-life exposure to perfluorooctane sulfonate

(2011) Ziquan Lv et al.   ENVIRONMENTAL TOXICOLOGY

Induction of apoptosis and CYP4A1 expression in Sprague-Dawley rats exposed to low doses of perfluorooctane sulfonate

(2011) Hyung-Sub Kim et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Comparative pharmacokinetics of perfluorooctanesulfonate (PFOS) in rats, mice, and monkeys

(2011) Shu-Ching Chang et al.   REPRODUCTIVE TOXICOLOGY

Multiplicity of nuclear receptor activation by PFOA and PFOS in primary human and rodent hepatocytes

(2011) J.A. Bjork et al.   TOXICOLOGY

Lipid metabolism and body composition in Gclm(−/−) mice

(2011) Eric L. Kendig et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Perfluoroalkyl and polyfluoroalkyl substances in the environment: Terminology, classification, and origins

(2011) Robert C Buck et al.   Integrated Environmental Assessment and Management

Perfluorooctanoic Acid, Perfluorooctanesulfonate, and Serum Lipids in Children and Adolescents

(2010) Stephanie J. Frisbee et al.   ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE

Hepatocellular hypertrophy and cell proliferation in Sprague–Dawley rats following dietary exposure to ammonium perfluorooctanoate occurs through increased activation of the xenosensor nuclear receptors PPARα and CAR/PXR

(2010) Clifford R. Elcombe et al.   ARCHIVES OF TOXICOLOGY

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

Perfluoroalkyl chemicals and human fetal development: An epidemiologic review with clinical and toxicological perspectives

(2009) Geary W. Olsen et al.   REPRODUCTIVE TOXICOLOGY

Gene expression profiling in the liver and lung of perfluorooctane sulfonate-exposed mouse fetuses: Comparison to changes induced by exposure to perfluorooctanoic acid

(2009) Mitchell B. Rosen et al.   REPRODUCTIVE TOXICOLOGY

28-Day dietary exposure of mice to a low total dose (7mg/kg) of perfluorooctanesulfonate (PFOS) alters neither the cellular compositions of the thymus and spleen nor humoral immune responses: Does the route of administration play a pivotal role in PFOS-induced immunotoxicity?

(2009) Mousumi Rahman Qazi et al.   TOXICOLOGY

A First Global Production, Emission, And Environmental Inventory For Perfluorooctane Sulfonate

(2008) Alexander G. Paul et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Altered Fatty Acid Homeostasis and Related Toxicologic Sequelae in Rats Exposed to Dietary Potassium Perfluorooctanesulfonate (PFOS)

(2008) Ivan Curran et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Regulation of glutathione synthesis

(2008) Shelly C. Lu   MOLECULAR ASPECTS OF MEDICINE

Perfluorooctane sulfonate-induced changes in fetal rat liver gene expression

(2008) James A. Bjork et al.   TOXICOLOGY

Oxidative mechanisms in the pathogenesis of alcoholic liver disease

(2007) Emanuele Albano   MOLECULAR ASPECTS OF MEDICINE