Involvement of the liver-gut peripheral neural axis in nonalcoholic fatty liver disease pathologies via hepatic HTR2A

The Regulatory Role of the Central and Peripheral Serotonin Network on Feeding Signals in Metabolic Diseases

(2022) Katsunori Nonogaki   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Modulation of serotonin in the gut-liver neural axis ameliorates the fatty and fibrotic changes in non-alcoholic fatty liver

(2021) Masayoshi Ko et al.   Disease Models & Mechanisms

Hepatic Nervous System in Development, Regeneration, and Disease

(2021) Bess M. Miller et al.   HEPATOLOGY

Overfeeding during development induces temporally-dependent changes in areas controlling food intake in the brains of male Wistar rats

(2021) Severina Cassia de Andrade Silva et al.   LIFE SCIENCES

Serotonergic Regulation of Hepatic Energy Metabolism

(2021) Jiwon Park et al.   Endocrinology and Metabolism

Liver tissue microbiome in NAFLD: next step in understanding the gut–liver axis?

(2020) Herbert Tilg et al.   GUT

Serotonergic regulation of energy metabolism in peripheral tissues

(2020) Wonsuk Choi et al.   JOURNAL OF ENDOCRINOLOGY

Ghrelin‐insulin‐like growth factor‐1 axis is activated via autonomic neural circuits in the non‐alcoholic fatty liver disease

(2020) Takuro Nagoya et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Diet differentially regulates enterochromaffin cell serotonin content, density and nutrient sensitivity in the mouse small and large intestine

(2020) Alyce M. Martin et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Gut-Derived Serotonin Contributes to the Progression of Non-Alcoholic Steatohepatitis via the Liver HTR2A/PPARγ2 Pathway

(2020) Lulu Wang et al.   Frontiers in Pharmacology

Gut barrier proteins mediate liver regulation by the effects of serotonin on the non-alcoholic fatty liver disease

(2020) Ke Zhang et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

The liver–brain–gut neural arc maintains the Treg cell niche in the gut

(2020) Toshiaki Teratani et al.   NATURE

The degree of hepatic steatosis associates with impaired cardiac and autonomic function

(2019) David Houghton et al.   JOURNAL OF HEPATOLOGY

The melanocortin pathway and control of appetite-progress and therapeutic implications

(2019) Giulia Baldini et al.   JOURNAL OF ENDOCRINOLOGY

Liver sympathetic denervation reverses obesity‐induced hepatic steatosis

(2019) Chansol Hurr et al.   JOURNAL OF PHYSIOLOGY-LONDON

Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression

(2019) Atsunori Kamiya et al.   NATURE NEUROSCIENCE

Regulation of compensatory β-cell proliferation by inter-organ networks from the liver to pancreatic β-cells

(2018) Junta Imai   ENDOCRINE JOURNAL

5-HT 2 receptor mediates high-fat diet-induced hepatic steatosis and very low density lipoprotein overproduction in rats

(2018) Xin Li et al.   Obesity Research & Clinical Practice

Autonomic nervous system network and liver regeneration

(2018) Kenya Kamimura et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Effect of a neural relay on liver regeneration in mice: activation of serotonin release from the gastrointestinal tract

(2018) Ryosuke Inoue et al.   FEBS Open Bio

Inhibition of Serotonin Synthesis Induces Negative Hepatic Lipid Balance

(2018) Jun Namkung et al.   Diabetes & Metabolism Journal

Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients

(2018) Erin A. Bohula et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial

(2018) Erin A Bohula et al.   LANCET

Serotonin signals through a gut-liver axis to regulate hepatic steatosis

(2018) Wonsuk Choi et al.   Nature Communications

The Diverse Metabolic Roles of Peripheral Serotonin

(2017) Alyce M. Martin et al.   ENDOCRINOLOGY

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

(2017) Naga Chalasani et al.   HEPATOLOGY

Hepatic vagus nerve regulates Kupffer cell activation via α7 nicotinic acetylcholine receptor in nonalcoholic steatohepatitis

(2017) Takahiro Nishio et al.   JOURNAL OF GASTROENTEROLOGY

Targeting the gut-liver axis in liver disease

(2017) Reiner Wiest et al.   JOURNAL OF HEPATOLOGY

Nerves switch on angiogenic metabolism

(2017) Yoku Hayakawa et al.   SCIENCE

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Autonomic Nervous System and the Liver

(2016) Kei Mizuno et al.   HEPATOLOGY RESEARCH

Peripheral Serotonin: a New Player in Systemic Energy Homeostasis

(2015)   MOLECULES AND CELLS

Non-alcoholic fatty liver disease as a consequence of autonomic imbalance and circadian desynchronization

(2015) E. Sabath et al.   Obesity Reviews

Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis

(2014) Justin D Crane et al.   NATURE MEDICINE

Acute High Fat Diet Consumption Activates the Mesolimbic Circuit and Requires Orexin Signaling in a Mouse Model

(2014) Spring Valdivia et al.   PLoS One

Computed Tomography Scans in the Evaluation of Fatty Liver Disease in a Population Based Study

(2012) Irfan Zeb et al.   ACADEMIC RADIOLOGY

GH-independent IGF-I action is essential to prevent the development of nonalcoholic steatohepatitis in a GH-deficient rat model

(2012) Hitoshi Nishizawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Melanocortin 4 Receptor–Deficient Mice as a Novel Mouse Model of Nonalcoholic Steatohepatitis

(2011) Michiko Itoh et al.   AMERICAN JOURNAL OF PATHOLOGY

Imaging mass spectrometry reveals characteristic changes in triglyceride and phospholipid species in regenerating mouse liver

(2011) Norio Miyamura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NPY and MC4R Signaling Regulate Thyroid Hormone Levels during Fasting through Both Central and Peripheral Pathways

(2011) Kristen R. Vella et al.   Cell Metabolism

Serotonin Receptor Type 3 Antagonists Improve Obesity-Associated Fatty Liver Disease in Mice

(2011) S. Haub et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease

(2011) Mohammad R Ebrahimkhani et al.   NATURE MEDICINE

Biopsy-proven Nonsteatotic Liver in Adults: Estimation of Reference Range for Difference in Attenuation between the Liver and the Spleen at Nonenhanced CT

(2011) Yang Shin Park et al.   RADIOLOGY

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Brain serotonin system in the coordination of food intake and body weight

(2010) Daniel D. Lam et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The Expanded Biology of Serotonin

(2009) Miles Berger et al.   Annual Review of Medicine

IGF-I gene transfer to cirrhotic liver induces fibrolysis and reduces fibrogenesis leading to cirrhosis reversion in rats

(2009) Luciano Sobrevals et al.   HEPATOLOGY

The function of serotonin within the liver

(2008) Richard G. Ruddell et al.   JOURNAL OF HEPATOLOGY

Regulation of Pancreatic   Cell Mass by Neuronal Signals from the Liver

(2008) J. Imai et al.   SCIENCE