Ghrelin‐insulin‐like growth factor‐1 axis is activated via autonomic neural circuits in the non‐alcoholic fatty liver disease

Growth hormone acts on liver to stimulate autophagy, support glucose production, and preserve blood glucose in chronically starved mice

(2019) Fei Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression

(2019) Atsunori Kamiya et al.   NATURE NEUROSCIENCE

NAFLD in children: new genes, new diagnostic modalities and new drugs

(2019) Valerio Nobili et al.   Nature Reviews Gastroenterology & Hepatology

Current Status in Testing for Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH)

(2019) Hannah K. Drescher et al.   Cells

Analysis of peripheral ghrelin signaling via the vagus nerve in ghrelin receptor–restored GHSR-null mice

(2018) Tadashi Okada et al.   NEUROSCIENCE LETTERS

Autonomic nervous system network and liver regeneration

(2018) Kenya Kamimura et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Effect of a neural relay on liver regeneration in mice: activation of serotonin release from the gastrointestinal tract

(2018) Ryosuke Inoue et al.   FEBS Open Bio

A useful model to compare human and mouse growth hormone gene chromosomal structure, expression and regulation, and immune tolerance of human growth hormone analogues

(2018) Peter A. Cattini et al.   GROWTH HORMONE & IGF RESEARCH

Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis

(2017) Chia-Shan Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Is Ghrelin Synthesized in the Central Nervous System?

(2017) Agustina Cabral et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons

(2016) D. Gowanlock R. Tervo et al.   NEURON

IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent manner

(2016) Hitoshi Nishizawa et al.   Scientific Reports

Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice

(2015) Jose Cordoba-Chacon et al.   DIABETES

Long-term effects of growth hormone replacement therapy on liver function in adult patients with growth hormone deficiency

(2014) Ryusaku Matsumoto et al.   GROWTH HORMONE & IGF RESEARCH

Lower levels of insulin-like growth factor-1 standard deviation score are associated with histological severity of non-alcoholic fatty liver disease

(2014) Yoshio Sumida et al.   HEPATOLOGY RESEARCH

Early Effects of Liver Regeneration on Endocrine Pancreas: In Vivo Change in Islet Morphology and In Vitro Assessment of Systemic Effects on β-Cell Function and Viability in the Rat Model of Two-Thirds Hepatectomy

(2014) F. Moreau et al.   HORMONE AND METABOLIC RESEARCH

Behavioral and Neural Correlates of Acute and Scheduled Hunger in C57BL/6 Mice

(2014) Christian M. Gallardo et al.   PLoS One

GH-independent IGF-I action is essential to prevent the development of nonalcoholic steatohepatitis in a GH-deficient rat model

(2012) Hitoshi Nishizawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Essential roles of growth hormone (GH) and insulin-like growth factor-I (IGF-I) in the liver [Review]

(2012) Yutaka Takahashi   ENDOCRINE JOURNAL

Nonalcoholic fatty liver disease in adult hypopituitary patients with GH deficiency and the impact of GH replacement therapy

(2012) H. Nishizawa et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Melanocortin 4 Receptor–Deficient Mice as a Novel Mouse Model of Nonalcoholic Steatohepatitis

(2011) Michiko Itoh et al.   AMERICAN JOURNAL OF PATHOLOGY

Nonalcoholic fatty liver disease is associated with increased GHBP and reduced GH/IGF-I levels

(2011) Alessandra Fusco et al.   CLINICAL ENDOCRINOLOGY

Nonalcoholic Fatty Liver Disease Is Associated with Low Circulating Levels of Insulin-Like Growth Factor-I

(2011) Franco Arturi et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ghrelin in Central Neurons

(2009) F. Ferrini et al.   Current Neuropharmacology

IGF-I gene transfer to cirrhotic liver induces fibrolysis and reduces fibrogenesis leading to cirrhosis reversion in rats

(2009) Luciano Sobrevals et al.   HEPATOLOGY

Regulation of Pancreatic   Cell Mass by Neuronal Signals from the Liver

(2008) J. Imai et al.   SCIENCE