Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases

Heterogeneity of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer and potential effects on therapy in the CAPRI GOIM trial

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Inter- and intra-tumor profiling of multi-regional colon cancer and metastasis

(2015) Akihiro Kogita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Development of a semi-conductor sequencing-based panel for genotyping of colon and lung cancer by the Onconetwork consortium

(2015) Bastiaan BJ Tops et al.   BMC CANCER

ERBB4 is over-expressed in human colon cancer and enhances cellular transformation

(2015) Christopher S. Williams et al.   CARCINOGENESIS

Novel molecular insights from routine genotyping of colorectal carcinomas

(2015) Matthew D. Stachler et al.   HUMAN PATHOLOGY

Notch-1 Promotes Stemness and Epithelial to Mesenchymal Transition in Colorectal Cancer

(2015) Alexander W. Fender et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Genetic mutations in human rectal cancers detected by targeted sequencing

(2015) Jun Bai et al.   JOURNAL OF HUMAN GENETICS

Mutations in the RAS and PI3K pathways are associated with metastatic location in colorectal cancers

(2015) Yuan-Tzu Lan et al.   JOURNAL OF SURGICAL ONCOLOGY

AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants

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HER2 Activating Mutations Are Targets for Colorectal Cancer Treatment

(2015) S. M. Kavuri et al.   Cancer Discovery

Loss of Smad4 in colorectal cancer induces resistance to 5-fluorouracil through activating Akt pathway

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Ion Torrent next-generation sequencing for routine identification of clinically relevant mutations in colorectal cancer patients

(2014) Umberto Malapelle et al.   JOURNAL OF CLINICAL PATHOLOGY

RAS testing of colorectal carcinoma—a guidance document from the Association of Clinical Pathologists Molecular Pathology and Diagnostics Group

(2014) Newton ACS Wong et al.   JOURNAL OF CLINICAL PATHOLOGY

FBXW7 Mutations in Patients with Advanced Cancers: Clinical and Molecular Characteristics and Outcomes with mTOR Inhibitors

(2014) Denis L. Jardim et al.   PLoS One

Rapamycin inhibits FBXW7 loss-induced epithelial–mesenchymal transition and cancer stem cell-like characteristics in colorectal cancer cells

(2013) Yuli Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PIK3CA and PTEN Gene and Exon Mutation-Specific Clinicopathologic and Molecular Associations in Colorectal Cancer

(2013) F. L. Day et al.   CLINICAL CANCER RESEARCH

KRAS testing in metastatic colorectal carcinoma: challenges, controversies, breakthroughs and beyond

(2013) Umberto Malapelle et al.   JOURNAL OF CLINICAL PATHOLOGY

FBXW7 Mediates Chemotherapeutic Sensitivity and Prognosis in NSCLCs

(2013) Takehiko Yokobori et al.   MOLECULAR CANCER RESEARCH

Activating Mutations in HER2 : Neu Opportunities and Neu Challenges

(2013) Britta Weigelt et al.   Cancer Discovery

Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in LKB1-Mutant Lung Cancer

(2013) Y. Liu et al.   Cancer Discovery

SMAD2, SMAD3 and SMAD4 Mutations in Colorectal Cancer

(2012) N. I. Fleming et al.   CANCER RESEARCH

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2

(2012) H. Greulich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Genetics of Colorectal Cancer

(2011) Eric R. Fearon   Annual Review of Pathology-Mechanisms of Disease

Randomized, Phase III Trial of Panitumumab With Infusional Fluorouracil, Leucovorin, and Oxaliplatin (FOLFOX4) Versus FOLFOX4 Alone As First-Line Treatment in Patients With Previously Untreated Metastatic Colorectal Cancer: The PRIME Study

(2010) Jean-Yves Douillard et al.   JOURNAL OF CLINICAL ONCOLOGY