Endothelial ENPP2 (Ectonucleotide Pyrophosphatase/Phosphodiesterase 2) Increases Atherosclerosis in Female and Male Mice

Endothelial Cell Receptors in Tissue Lipid Uptake and Metabolism

(2021) Nada A. Abumrad et al.   CIRCULATION RESEARCH

The Expression Regulation and Biological Function of Autotaxin

(2021) Xiaotian Zhang et al.   Cells

Lysophospholipid Mediators in Health and Disease

(2021) Kuniyuki Kano et al.   Annual Review of Pathology-Mechanisms of Disease

Genetic deletion of Autotaxin from CD11b+ cells decreases the severity of experimental autoimmune encephalomyelitis

(2020) Ioanna Ninou et al.   PLoS One

Metabolic Dysregulation of the Lysophospholipid/autotaxin Axis in the Chromosome 9p21 Gene SNP rs10757274

(2020) Sven W. Meckelmann et al.   Circulation-Genomic and Precision Medicine

Atheroma-Specific Lipids in ldlr–/– and apoe–/– Mice Using 2D and 3D Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

(2020) Jianhua Cao et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies

(2020) Habtamu B. Beyene et al.   PLOS BIOLOGY

Autotaxin and chronic inflammatory diseases

(2019) Christiana Magkrioti et al.   JOURNAL OF AUTOIMMUNITY

Effects of diet and hyperlipidemia on levels and distribution of circulating lysophosphatidic acid

(2019) Maria Kraemer et al.   JOURNAL OF LIPID RESEARCH

Lysophosphatidic Acid Signaling in Obesity and Insulin Resistance

(2018) et al.   Nutrients

Autotaxin-β interaction with the cell surface via syndecan-4 impacts on cancer cell proliferation and metastasis

(2018) Raphael Leblanc et al.   Oncotarget

Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ

(2017) Hua Mao et al.   Nature Communications

Autotaxin–Lysophosphatidic Acid Axis Acts Downstream of Apoprotein B Lipoproteins in Endothelial CellsHighlights

(2016) Liron Gibbs-Bar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibition of lysophosphatidic acid receptors 1 and 3 attenuates atherosclerosis development in LDL-receptor deficient mice

(2016) Eva Kritikou et al.   Scientific Reports

Autotaxin Derived From Lipoprotein(a) and Valve Interstitial Cells Promotes Inflammation and Mineralization of the Aortic ValveCLINICAL PERSPECTIVE

(2015) Rihab Bouchareb et al.   CIRCULATION

Endothelial Hypoxia-Inducible Factor-1α Promotes Atherosclerosis and Monocyte Recruitment by Upregulating MicroRNA-19a

(2015) Shamima Akhtar et al.   HYPERTENSION

Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate

(2015) Matthew G. K. Benesch et al.   JOURNAL OF LIPID RESEARCH

Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis

(2015) Mohamad Navab et al.   JOURNAL OF LIPID RESEARCH

Quantitation of phosphatidic acid and lysophosphatidic acid molecular species using hydrophilic interaction liquid chromatography coupled to electrospray ionization high resolution mass spectrometry

(2014) Alexander Triebl et al.   JOURNAL OF CHROMATOGRAPHY A

MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1

(2014) Andreas Schober et al.   NATURE MEDICINE

Transgenic 6F tomatoes act on the small intestine to prevent systemic inflammation and dyslipidemia caused by Western diet and intestinally derived lysophosphatidic acid

(2013) Mohamad Navab et al.   JOURNAL OF LIPID RESEARCH

ApoE and the role of very low density lipoproteins in adipose tissue inflammation

(2012) Jiali Wang et al.   ATHEROSCLEROSIS

Lysophosphatidic acid in atherosclerotic diseases

(2012) Andreas Schober et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lipoprotein-Derived Lysophosphatidic Acid Promotes Atherosclerosis by Releasing CXCL1 from the Endothelium

(2011) Zhe Zhou et al.   Cell Metabolism

Binding of Autotaxin to Integrins Localizes Lysophosphatidic Acid Production to Platelets and Mammalian Cells

(2011) Zachary Fulkerson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insights into autotaxin: how to produce and present a lipid mediator

(2011) Wouter H. Moolenaar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural basis of substrate discrimination and integrin binding by autotaxin

(2011) Jens Hausmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

(2011) Hiroshi Nishimasu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATX expression and LPA signalling are vital for the development of the nervous system

(2010) Stella Fotopoulou et al.   DEVELOPMENTAL BIOLOGY

Autotaxin expression and its connection with the TNF-alpha-NF-κB axis in human hepatocellular carcinoma

(2010) Jian-Min Wu et al.   Molecular Cancer

Oxidized LDL: Diversity, Patterns of Recognition, and Pathophysiology

(2009) Irena Levitan et al.   ANTIOXIDANTS & REDOX SIGNALING

Involvement of the Lysophosphatidic Acid-Generating Enzyme Autotaxin in Lymphocyte-Endothelial Cell Interactions

(2008) Tae Nakasaki et al.   AMERICAN JOURNAL OF PATHOLOGY

Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice

(2008) Iordanes Karagiannides et al.   FEBS Journal

Measurement of plasma lysophosphatidic acid concentration in healthy subjects: strong correlation with lysophospholipase D activity

(2008) S. Hosogaya et al.   ANNALS OF CLINICAL BIOCHEMISTRY