Drug Repurposing by Siderophore Conjugation: Synthesis and Biological Evaluation of Siderophore‐Methotrexate Conjugates as Antibiotics
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Drug Repurposing by Siderophore Conjugation: Synthesis and Biological Evaluation of Siderophore‐Methotrexate Conjugates as Antibiotics
Authors
Keywords
-
Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2022-07-09
DOI
10.1002/anie.202204139
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Iron Acquisition Systems of Gram-negative Bacterial Pathogens Define TonB-Dependent Pathways to Novel Antibiotics
- (2021) Phillip E. Klebba et al. CHEMICAL REVIEWS
- Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens
- (2021) Lukas Pinkert et al. JOURNAL OF MEDICINAL CHEMISTRY
- Repurposed anti-cancer drugs: the future for anti-infective therapy?
- (2020) Héctor Quezada et al. Expert Review of Anti-Infective Therapy
- Advances in ‘Trojan horse’ strategies in antibiotic delivery systems
- (2020) Alexandra Dassonville-Klimpt et al. Future Medicinal Chemistry
- The Pneumococcal Iron Uptake Protein a (PiuA) Specifically Recognizes Tetradentate FeIII bis- and Mono-Catechol Complexes
- (2020) Yifan Zhang et al. JOURNAL OF MOLECULAR BIOLOGY
- Narrow-Spectrum Antibacterial Agents—Benefits and Challenges
- (2020) Richard A. Alm et al. Antibiotics-Basel
- Artificial intelligence, drug repurposing and peer review
- (2020) Jeremy M. Levin et al. NATURE BIOTECHNOLOGY
- Platform to Discover Protease-Activated Antibiotics and Application to Siderophore–Antibiotic Conjugates
- (2020) Jonathan H. Boyce et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- DHFR Inhibitors: Reading the Past for Discovering Novel Anticancer Agents
- (2019) Maria Raimondi et al. MOLECULES
- Delivery Systems as Vital Tools in Drug Repurposing
- (2019) Tori Czech et al. AAPS PHARMSCITECH
- Drug delivery systems designed to overcome antimicrobial resistance
- (2019) Thanh‐Nhat Pham et al. MEDICINAL RESEARCH REVIEWS
- Toward Broad Spectrum DHFR inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin-Resistant Staphylococcus aureus
- (2019) Stephanie M. Reeve et al. ACS Infectious Diseases
- Antibiotic repurposing: bis-catechol- and mixed ligand (bis-catechol-mono-hydroxamate)-teicoplanin conjugates are active against multidrug resistant Acinetobacter baumannii
- (2019) Manuka Ghosh et al. JOURNAL OF ANTIBIOTICS
- Evaluation of a reducible disulfide linker for siderophore-mediated delivery of antibiotics
- (2018) Wilma Neumann et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- A Synthetic Dual Drug Sideromycin Induces Gram-Negative Bacteria To Commit Suicide with a Gram-Positive Antibiotic
- (2018) Rui Liu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Esterase-Catalyzed Siderophore Hydrolysis Activates an Enterobactin–Ciprofloxacin Conjugate and Confers Targeted Antibacterial Activity
- (2018) Wilma Neumann et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Total synthesis and antimicrobial evaluation of natural albomycins against clinical pathogens
- (2018) Zihua Lin et al. Nature Communications
- Siderophore–fluoroquinolone conjugates containing potential reduction-triggered linkers for drug release: synthesis and antibacterial activity
- (2015) Cheng Ji et al. BIOMETALS
- Evaluation of (acyloxy)alkyl ester linkers for antibiotic release from siderophore–antibiotic conjugates
- (2015) Tengfei Zheng et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- A return to the pre-antimicrobial era?
- (2015) S. Baker SCIENCE
- Direct Evidence of Iron Uptake by the Gram-Positive Siderophore-Shuttle Mechanism without Iron Reduction
- (2014) Tatsuya Fukushima et al. ACS Chemical Biology
- Tuning the Intracellular Bacterial Targeting of Peptidic Vectors
- (2013) Eric K. Lei et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Structures of Streptococcus pneumoniae PiaA and Its Complex with Ferrichrome Reveal Insights into the Substrate Binding and Release of High Affinity Iron Transporters
- (2013) Wang Cheng et al. PLoS One
- Chemical syntheses and in vitro antibacterial activity of two desferrioxamine B-ciprofloxacin conjugates with potential esterase and phosphatase triggered drug release linkers
- (2012) Cheng Ji et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Maximizing the Therapeutic Window of an Antimicrobial Drug by Imparting Mitochondrial Sequestration in Human Cells
- (2011) Mark P. Pereira et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now