An Activity‐Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO − ) in the Alzheimer's Disease Brain

A Fluorogenic ONOO–-Triggered Carbon Monoxide Donor for Mitigating Brain Ischemic Damage

(2022) Linfeng Xing et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Psychosis in Alzheimer disease — mechanisms, genetics and therapeutic opportunities

(2022) Zahinoor Ismail et al.   Nature Reviews Neurology

Activity-Based Fluorescent Molecular Logic Gate Probe for Dynamic Tracking of Mitophagy Induced by Oxidative Stress

(2021) Zhipeng Liu et al.   ANALYTICAL CHEMISTRY

Alzheimer's disease

(2021) Philip Scheltens et al.   LANCET

Alzheimer’s disease and its treatment by different approaches: A review

(2021) Sukriti Srivastava et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Dual-locked spectroscopic probes for sensing and therapy

(2021) Luling Wu et al.   Nature Reviews Chemistry

Dual-Channel Imaging of Amyloid-β Plaques and Peroxynitrite To Illuminate Their Correlations in Alzheimer’s Disease Using a Unimolecular Two-Photon Fluorescent Probe

(2021) Xilei Xie et al.   ANALYTICAL CHEMISTRY

Recent advances in reaction-based fluorescent probes for the detection of central nervous system-related pathologies in vivo

(2021) Ya-Lin Qi et al.   COORDINATION CHEMISTRY REVIEWS

Dual-Channel Fluorescent Probe for the Simultaneous Monitoring of Peroxynitrite and Adenosine-5′-triphosphate in Cellular Applications

(2021) Luling Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A novel fluorescent probe for the detection of peroxynitrite and its application in acute liver injury model

(2021) Chen Jin et al.   Redox Biology

New rhodamines with changeable π-conjugation for lengthening fluorescence wavelengths and imaging peroxynitrite

(2021) Haolin Zhang et al.   Chem

Activity-based fluorescence probes for pathophysiological peroxynitrite fluxes

(2021) Zhiqiang Mao et al.   COORDINATION CHEMISTRY REVIEWS

Ultrafast Detection of Peroxynitrite in Parkinson’s Disease Models Using a Near-Infrared Fluorescent Probe

(2020) Qian Sun et al.   ANALYTICAL CHEMISTRY

Rabies Virus‐Inspired Metal–Organic Frameworks (MOFs) for Targeted Imaging and Chemotherapy of Glioma

(2020) Chaoqiang Qiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorescent Diagnostic Probes in Neurodegenerative Diseases

(2020) Jin Zhou et al.   ADVANCED MATERIALS

Activatable Two-Photon Near-Infrared Fluorescent Probe Tailored toward Peroxynitrite In Vivo Imaging in Tumors

(2020) Weiwei Wang et al.   ANALYTICAL CHEMISTRY

Activity‐Based NIR Enzyme Fluorescent Probes for the Diagnosis of Tumors and Image‐Guided Surgery

(2020) Juyoung Yoon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visualizing Peroxynitrite in Microvessels of the Brain with Stroke Using an Engineered Highly Specific Fluorescent Probe

(2020) Jianhua Xiong et al.   ACS Sensors

Frontiers in Probing Alzheimer’s Disease Biomarkers with Fluorescent Small Molecules

(2019) Yong Woong Jun et al.   ACS Central Science

Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease

(2019) D. Allan Butterfield et al.   NATURE REVIEWS NEUROSCIENCE

The impact of curcumin and its modified formulations on Alzheimer's disease

(2019) Tahereh Farkhondeh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Harnessing Intramolecular Rotation to Enhance Two-photon Imaging of Aβ Plaques Through Minimizing Background Fluorescence

(2019) Jinwoo Shin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hybrid Rhodamine Fluorophores in the Visible-NIR Region for Biological Imaging

(2019) Liulin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A brief history of “Alzheimer disease”

(2019) David S. Knopman et al.   NEUROLOGY

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

(2019) Justin M. Long et al.   CELL

The Blood–Brain Barrier (BBB) Score

(2019) Mayuri Gupta et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Dual-Modal Molecular Probe for Near-Infrared Fluorescence and Photoacoustic Imaging of Peroxynitrite

(2018) Jianjian Zhang et al.   ANALYTICAL CHEMISTRY

Shedding light on tau protein aggregation: the progress in developing highly selective fluorophores

(2018) Peter Verwilst et al.   CHEMICAL SOCIETY REVIEWS

A General Method To Increase Stokes Shift by Introducing Alternating Vibronic Structures

(2018) Tian-Bing Ren et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases

(2018) Denzil Furtado et al.   ADVANCED MATERIALS

Imaging the evolution and pathophysiology of Alzheimer disease

(2018) William Jagust   NATURE REVIEWS NEUROSCIENCE

Oxalate-curcumin–based probe for micro- and macroimaging of reactive oxygen species in Alzheimer’s disease

(2017) Jian Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased Iron and Free Radical Generation in Preclinical Alzheimer Disease and Mild Cognitive Impairment

(2017) Mark A. Smith et al.   JOURNAL OF ALZHEIMERS DISEASE

Transforming the recognition site of 4-hydroxyaniline into 4-methoxyaniline grafted onto a BODIPY core switches the selective detection of peroxynitrite to hypochlorous acid

(2016) Chunchang Zhao et al.   CHEMICAL COMMUNICATIONS

Selective Visualization of the Endogenous Peroxynitrite in an Inflamed Mouse Model by a Mitochondria-Targetable Two-Photon Ratiometric Fluorescent Probe

(2016) Dan Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FRET-Based Mito-Specific Fluorescent Probe for Ratiometric Detection and Imaging of Endogenous Peroxynitrite: Dyad of Cy3 and Cy5

(2016) Xiaotong Jia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A rationally designed rhodamine-based fluorescent probe for molecular imaging of peroxynitrite in live cells and tissues

(2016) Tao Peng et al.   Chemical Science

A mitochondria-targetable fluorescent probe for peroxynitrite: fast response and high selectivity

(2015) Hongxing Zhang et al.   CHEMICAL COMMUNICATIONS

PET/SPECT imaging agents for neurodegenerative diseases

(2014) Lin Zhu et al.   CHEMICAL SOCIETY REVIEWS

Smart Near-Infrared Fluorescence Probes with Donor–Acceptor Structure for in Vivo Detection of β-Amyloid Deposits

(2014) Mengchao Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Imaging of Peroxynitrite with HKGreen-4 in Live Cells and Tissues

(2014) Tao Peng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reversible Near-Infrared Fluorescent Probe Introducing Tellurium to Mimetic Glutathione Peroxidase for Monitoring the Redox Cycles between Peroxynitrite and Glutathione in Vivo

(2013) Fabiao Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aminonaphthalene 2-Cyanoacrylate (ANCA) Probes Fluorescently Discriminate between Amyloid-β and Prion Plaques in Brain

(2012) Kevin Cao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

(2008) Lars Lannfelt et al.   LANCET NEUROLOGY

Biomarkers of Alzheimer's disease

(2008) Rebecca Craig-Schapiro et al.   NEUROBIOLOGY OF DISEASE