Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts

Developmental deficits and staging of dynamics of age associated Alzheimer’s disease neurodegeneration and neuronal loss in subjects with Down syndrome

(2022) Jerzy Wegiel et al.   Acta Neuropathologica Communications

Patterns of amygdala region pathology in LATE-NC: subtypes that differ with regard to TDP-43 histopathology, genetic risk factors, and comorbid pathologies

(2022) Matthew D. Cykowski et al.   ACTA NEUROPATHOLOGICA

New insights into the genetic etiology of Alzheimer’s disease and related dementias

(2022) Céline Bellenguez et al.   NATURE GENETICS

Limbic‐predominant age‐related TDP‐43 encephalopathy neuropathologic change and microvascular pathologies in community‐dwelling older persons

(2021) Sonal Agrawal et al.   BRAIN PATHOLOGY

What is ‘Alzheimer's disease’? The neuropathological heterogeneity of clinically defined Alzheimer's dementia

(2021) Rupal I. Mehta et al.   CURRENT OPINION IN NEUROLOGY

TAR DNA-Binding Protein 43 Is Associated with Rate of Memory and Functional and Global Cognitive Decline in the Decade Prior to Death

(2021) Marina Buciuc et al.   JOURNAL OF ALZHEIMERS DISEASE

Application of deep learning to understand resilience to Alzheimer's disease pathology

(2021) Cecilia S. Lee et al.   BRAIN PATHOLOGY

Space-occupying brain lesions, trauma-related tau astrogliopathy, and ARTAG: a report of two cases and a literature review

(2021) Adam D. Bachstetter et al.   Acta Neuropathologica Communications

Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is independently associated with dementia and strongly associated with arteriolosclerosis in the oldest-old

(2021) William T. Harrison et al.   ACTA NEUROPATHOLOGICA

LATE Neuropathologic Changes with Little or No Alzheimer Disease is Common and is Associated with Cognitive Impairment but Not Frontotemporal Dementia

(2021) Peter T Nelson   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Analysis of genes (TMEM106B, GRN, ABCC9, KCNMB2, and APOE) implicated in risk for LATE-NC and hippocampal sclerosis provides pathogenetic insights: a retrospective genetic association study

(2021) Adam J. Dugan et al.   Acta Neuropathologica Communications

Recent update on the heterogeneity of the Alzheimer’s disease spectrum

(2021) Kurt A. Jellinger   JOURNAL OF NEURAL TRANSMISSION

TDP-43 Pathology in Alzheimer’s Disease

(2021) Axel Meneses et al.   Molecular Neurodegeneration

Changes in prevalence of cognitive impairment and associated risk factors 2000–2015 in São Paulo, Brazil

(2021) Fabiana Silva Ribeiro et al.   BMC Geriatrics

Limbic-predominant Age-related TDP-43 Encephalopathy and Distinct Longitudinal Profiles of Domain-specific Literacy

(2020) Lei Yu et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

TDP-43 Related Neuropathologies and Phosphorylation State: Associations with Age and Clinical Dementia in the Cambridge City over-75s Cohort

(2020) Sally Hunter et al.   JOURNAL OF ALZHEIMERS DISEASE

Distinct molecular patterns of TDP-43 pathology in Alzheimer’s disease: relationship with clinical phenotypes

(2020) Sandra O. Tomé et al.   Acta Neuropathologica Communications

Limbic-predominant age-related TDP-43 encephalopathy in black and white decedents

(2020) Sukriti Nag et al.   NEUROLOGY

Prevalence and Clinical Phenotype of Quadruple Misfolded Proteins in Older Adults

(2020) Shama Karanth et al.   JAMA Neurology

Hippocampal sclerosis, TDP‐43, and the duration of the symptoms of dementia of AD patients

(2020) Oscar L. Lopez et al.   Annals of Clinical and Translational Neurology

Brain arteriolosclerosis

(2020) Brittney L. Blevins et al.   ACTA NEUROPATHOLOGICA

Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy

(2020) Yuriko Katsumata et al.   ACTA NEUROPATHOLOGICA

Limbic-predominant age-related TDP-43 encephalopathy differs from frontotemporal lobar degeneration

(2020) John L Robinson et al.   BRAIN

Association of TDP-43 proteinopathy, cerebral amyloid angiopathy, and Lewy bodies with cognitive impairment in individuals with or without Alzheimer’s disease neuropathology

(2020) David X. Thomas et al.   Scientific Reports

Pathological, imaging and genetic characteristics support the existence of distinct TDP-43 types in non-FTLD brains

(2019) Keith A. Josephs et al.   ACTA NEUROPATHOLOGICA

Tau and TDP-43 proteinopathies: kindred pathologic cascades and genetic pleiotropy

(2019) Yevgen Chornenkyy et al.   LABORATORY INVESTIGATION

Neuropathological Diagnoses of Demented Hispanic, Black, and Non-Hispanic White Decedents Seen at an Alzheimer’s Disease Center

(2019) Teresa Jenica Filshtein et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuropathological lesions in the very old: results from a large brazilian autopsy study

(2019) Claudia K. Suemoto et al.   BRAIN PATHOLOGY

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

(2019) Peter T Nelson et al.   BRAIN

TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels

(2019) Peter T. Nelson et al.   NEUROBIOLOGY OF DISEASE

LATE to the PART-y

(2019) Keith A Josephs et al.   BRAIN

Reply: LATE to the PART-y

(2019) Peter T Nelson et al.   BRAIN

Resistance and resilience to Alzheimer’s disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort

(2019) Caitlin S. Latimer et al.   Acta Neuropathologica Communications

Putative risk alleles for LATE‐NC with hippocampal sclerosis in population‐representative autopsy cohorts

(2019) Suvi R. K. Hokkanen et al.   BRAIN PATHOLOGY

Neuropathology of Lewy body disease: Clinicopathological crosstalk between typical and atypical cases

(2019) Tomoya Kon et al.   NEUROPATHOLOGY

Chameleons and mimics: Progressive supranuclear palsy and corticobasal degeneration

(2019) Maya Mimuro et al.   NEUROPATHOLOGY

Non-Alzheimer’s contributions to dementia and cognitive resilience in The 90+ Study

(2018) John L. Robinson et al.   ACTA NEUROPATHOLOGICA

Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

(2018) John L Robinson et al.   BRAIN

Hippocampal Sclerosis in the Oldest Old: A Finnish Population-Based Study

(2018) Mia Kero et al.   JOURNAL OF ALZHEIMERS DISEASE

TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer’s disease

(2018) Sukriti Nag et al.   Acta Neuropathologica Communications

Epidemiological Neuropathology: The MRC Cognitive Function and Aging Study Experience

(2018) Stephen B. Wharton et al.   JOURNAL OF ALZHEIMERS DISEASE

TDP-43 Pathology in the Population: Prevalence and Associations with Dementia and Age

(2018) Hannah A.D. Keage et al.   JOURNAL OF ALZHEIMERS DISEASE

Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study

(2018) Hyun-Sik Yang et al.   LANCET NEUROLOGY

Attributable risk of Alzheimer's dementia attributed to age-related neuropathologies

(2018) Patricia A. Boyle et al.   ANNALS OF NEUROLOGY

TDP-43 Neuropathologic Associations in the Nun Study and the Honolulu-Asia Aging Study

(2018) Margaret E. Flanagan et al.   JOURNAL OF ALZHEIMERS DISEASE

Association of Apolipoprotein E ε4 With Transactive Response DNA-Binding Protein 43

(2018) Alexandra M. Wennberg et al.   JAMA Neurology

Resistance to Alzheimer Disease Neuropathologic Changes and Apparent Cognitive Resilience in the Nun and Honolulu-Asia Aging Studies

(2017) Caitlin S. Latimer et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD

(2017) Sukriti Nag et al.   NEUROLOGY

Prevalence of transactive response DNA-binding protein 43 (TDP-43) proteinopathy in cognitively normal older adults: systematic review and meta-analysis

(2017) C. Nascimento et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Neuropathological diagnoses and clinical correlates in older adults in Brazil: A cross-sectional study

(2017) Claudia K. Suemoto et al.   PLOS MEDICINE

Amyotrophic lateral sclerosis - frontotemporal spectrum disorder (ALS-FTSD): Revised diagnostic criteria

(2017) Michael J. Strong et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Neuropathological Correlates of Dementia in Over-80-Year-Old Brain Donors from the Population-Based Cambridge City over-75s Cohort (CC75C) Study

(2017) Carol Brayne et al.   JOURNAL OF ALZHEIMERS DISEASE

The Neuropathology of Older Persons with and Without Dementia from Community versus Clinic Cohorts

(2017) Julie A. Schneider et al.   JOURNAL OF ALZHEIMERS DISEASE

Updated TDP-43 in Alzheimer’s disease staging scheme

(2016) Keith A. Josephs et al.   ACTA NEUROPATHOLOGICA

Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease

(2016) Thomas J. Montine et al.   Alzheimers & Dementia

TDP-43 stage, mixed pathologies, and clinical Alzheimer’s-type dementia

(2016) Bryan D. James et al.   BRAIN

TDP-43 pathology in Alzheimer's disease, dementia with Lewy bodies and ageing

(2016) Kirsty E. McAleese et al.   BRAIN PATHOLOGY

Regional MRI Diffusion, White-Matter Hyperintensities, and Cognitive Function in Alzheimer's Disease and Vascular Dementia

(2016) Claudia Altamura et al.   Journal of Clinical Neurology

Prevalence, characteristics, and survival of frontotemporal lobar degeneration syndromes

(2016) Ian T.S. Coyle-Gilchrist et al.   NEUROLOGY

Peripheral (deep) but not periventricular MRI white matter hyperintensities are increased in clinical vascular dementia compared to Alzheimer's disease

(2016) Charles D. Smith et al.   Brain and Behavior

PART is part of Alzheimer disease

(2015) Charles Duyckaerts et al.   ACTA NEUROPATHOLOGICA

Hippocampal sclerosis and TDP-43 pathology in aging and Alzheimer disease

(2015) Sukriti Nag et al.   ANNALS OF NEUROLOGY

Higher Prevalence of TDP-43 Proteinopathy in Cognitively Normal Asians: A Clinicopathological Study on a Multiethnic Sample

(2015) Camila Nascimento et al.   BRAIN PATHOLOGY

Cerebral amyloid angiopathy and its co-occurrence with Alzheimer's disease and other cerebrovascular neuropathologic changes

(2015) Willa D. Brenowitz et al.   NEUROBIOLOGY OF AGING

TheTMEM106Blocus and TDP-43 pathology in older persons without FTLDAuthor Response

(2015) Dennis W. Dickson et al.   NEUROLOGY

Multiple pathologies are common and related to dementia in the oldest-old

(2015) Claudia H. Kawas et al.   NEUROLOGY

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

Differential clinicopathologic and genetic features of late-onset amnestic dementias

(2014) Melissa E. Murray et al.   ACTA NEUROPATHOLOGICA

TDP-43 is a key player in the clinical features associated with Alzheimer’s disease

(2014) Keith A. Josephs et al.   ACTA NEUROPATHOLOGICA

Prevalence of mixed pathologies in the aging brain

(2014) Jasmin Rahimi et al.   Alzheimers Research & Therapy

Non-Alzheimer neurodegenerative pathologies and their combinations are more frequent than commonly believed in the elderly brain: a community-based autopsy series

(2013) Gabor G. Kovacs et al.   ACTA NEUROPATHOLOGICA

University of Kentucky Sanders-Brown Healthy Brain Aging Volunteers: Donor Characteristics, Procedures and Neuropathology

(2013) Frederick A. Schmitt et al.   Current Alzheimer Research

Overview and Findings from the Religious Orders Study

(2013) David A. Bennett et al.   Current Alzheimer Research

A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the Cognitive Function and Ageing Study I and II

(2013) Fiona E Matthews et al.   LANCET

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease

(2012) N. J. Rutherford et al.   NEUROLOGY

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Estimating the Number of Persons with Frontotemporal Lobar Degeneration in the US Population

(2011) David S. Knopman et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

(2011) Heiko Braak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study

(2011) Melissa E Murray et al.   LANCET NEUROLOGY

Preclinical AD Workgroup staging: pathological correlates and potential challenges

(2011) Gregory A. Jicha et al.   NEUROBIOLOGY OF AGING

Apolipoprotein E ε4 Prevalence in Alzheimer’s Disease Patients Varies across Global Populations: A Systematic Literature Review and Meta-Analysis

(2010) Sheila Crean et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Assessment of β-amyloid deposits in human brain: a study of the BrainNet Europe Consortium

(2009) Irina Alafuzoff et al.   ACTA NEUROPATHOLOGICA

Correlation of Clinical Features With Argyrophilic Grains at Autopsy

(2009) Marwan N. Sabbagh et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Enduring involvement of tau, β-amyloid, α-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism–dementia complex of Guam (ALS/PDC)

(2008) Judith Miklossy et al.   ACTA NEUROPATHOLOGICA

Inter-laboratory comparison of neuropathological assessments of β-amyloid protein: a study of the BrainNet Europe consortium

(2008) Irina Alafuzoff et al.   ACTA NEUROPATHOLOGICA

Staging of Neurofibrillary Pathology in Alzheimer's Disease: A Study of the BrainNet Europe Consortium

(2008) Irina Alafuzoff et al.   BRAIN PATHOLOGY

Modeling the Association between 43 Different Clinical and Pathological Variables and the Severity of Cognitive Impairment in a Large Autopsy Cohort of Elderly Persons

(2008) Peter T. Nelson et al.   BRAIN PATHOLOGY

Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia

(2008) Rosa Rademakers et al.   HUMAN MOLECULAR GENETICS

Parenchymal and vascular Aβ-deposition and its effects on the degeneration of neurons and cognition in Alzheimer's disease

(2008) Dietmar Rudolf Thal et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Association between Deposition of Beta-Amyloid and Pathological Prion Protein in Sporadic Creutzfeldt-Jakob Disease

(2008) Laura Debatin et al.   Neurodegenerative Diseases

The Mayo Clinic Study of Aging: Design and Sampling, Participation, Baseline Measures and Sample Characteristics

(2008) Rosebud O. Roberts et al.   NEUROEPIDEMIOLOGY

Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype

(2008) K. A. Josephs et al.   NEUROLOGY