Limbic-predominant age-related TDP-43 encephalopathy differs from frontotemporal lobar degeneration

Pathological, imaging and genetic characteristics support the existence of distinct TDP-43 types in non-FTLD brains

(2019) Keith A. Josephs et al.   ACTA NEUROPATHOLOGICA

Tau and TDP-43 proteinopathies: kindred pathologic cascades and genetic pleiotropy

(2019) Yevgen Chornenkyy et al.   LABORATORY INVESTIGATION

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

(2019) Peter T Nelson et al.   BRAIN

Chronic Traumatic Encephalopathy (CTE) Is Absent From a European Community-Based Aging Cohort While Cortical Aging-Related Tau Astrogliopathy (ARTAG) Is Highly Prevalent

(2019) Shelley L Forrest et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels

(2019) Peter T. Nelson et al.   NEUROBIOLOGY OF DISEASE

LATE to the PART-y

(2019) Keith A Josephs et al.   BRAIN

Reply: LATE to the PART-y

(2019) Peter T Nelson et al.   BRAIN

Faster cognitive decline in dementia due to Alzheimer disease with clinically undiagnosed Lewy body disease

(2019) Michael Malek-Ahmadi et al.   PLoS One

Antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration

(2019) Alexandre Bejanin et al.   BRAIN

Chronic traumatic encephalopathy neuropathology might not be inexorably progressive or unique to repetitive neurotrauma

(2019) Grant L Iverson et al.   BRAIN

Non-Alzheimer’s contributions to dementia and cognitive resilience in The 90+ Study

(2018) John L. Robinson et al.   ACTA NEUROPATHOLOGICA

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

(2018) John L Robinson et al.   BRAIN

Assessing the Limitations and Biases in the Current Understanding of Chronic Traumatic Encephalopathy

(2018) Nicole Schwab et al.   JOURNAL OF ALZHEIMERS DISEASE

TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer’s disease

(2018) Sukriti Nag et al.   Acta Neuropathologica Communications

TDP-43 Pathology in the Population: Prevalence and Associations with Dementia and Age

(2018) Hannah A.D. Keage et al.   JOURNAL OF ALZHEIMERS DISEASE

Association of Apolipoprotein E ε4 With Transactive Response DNA-Binding Protein 43

(2018) Alexandra M. Wennberg et al.   JAMA Neurology

Dichotomous scoring of TDP-43 proteinopathy from specific brain regions in 27 academic research centers: associations with Alzheimer’s disease and cerebrovascular disease pathologies

(2018) Yuriko Katsumata et al.   Acta Neuropathologica Communications

Detergent Insoluble Proteins and Inclusion Body-Like Structures Immunoreactive for PRKDC/DNA-PK/DNA-PKcs, FTL, NNT, and AIFM1 in the Amygdala of Cognitively Impaired Elderly Persons

(2017) Jozsef Gal et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer's disease: a longitudinal retrospective study

(2017) Keith A Josephs et al.   LANCET NEUROLOGY

TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD

(2017) Sukriti Nag et al.   NEUROLOGY

Amyotrophic lateral sclerosis - frontotemporal spectrum disorder (ALS-FTSD): Revised diagnostic criteria

(2017) Michael J. Strong et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Updated TDP-43 in Alzheimer’s disease staging scheme

(2016) Keith A. Josephs et al.   ACTA NEUROPATHOLOGICA

“New Old Pathologies”: AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS)

(2016) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Prevalence, characteristics, and survival of frontotemporal lobar degeneration syndromes

(2016) Ian T.S. Coyle-Gilchrist et al.   NEUROLOGY

Hippocampal sclerosis and TDP-43 pathology in aging and Alzheimer disease

(2015) Sukriti Nag et al.   ANNALS OF NEUROLOGY

Neuropathologic correlates of regional brain volumes in a community cohort of older adults

(2015) Aikaterini Kotrotsou et al.   NEUROBIOLOGY OF AGING

TheTMEM106Blocus and TDP-43 pathology in older persons without FTLDAuthor Response

(2015) Dennis W. Dickson et al.   NEUROLOGY

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

Hippocampal sclerosis in Lewy body disease is a TDP-43 proteinopathy similar to FTLD-TDP Type A

(2014) Naoya Aoki et al.   ACTA NEUROPATHOLOGICA

Differential clinicopathologic and genetic features of late-onset amnestic dementias

(2014) Melissa E. Murray et al.   ACTA NEUROPATHOLOGICA

TDP-43 in Alzheimer’s disease is not associated with clinical FTLD or Parkinsonism

(2014) Youngsin Jung et al.   JOURNAL OF NEUROLOGY

The neuropathology associated with repeat expansions in the C9ORF72 gene

(2013) Ian R. A. Mackenzie et al.   ACTA NEUROPATHOLOGICA

Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease

(2013) Peter T. Nelson et al.   ACTA NEUROPATHOLOGICA

A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank

(2013) Jon B. Toledo et al.   Alzheimers & Dementia

Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing

(2013) Janna H. Neltner et al.   BRAIN

Clinicopathologic correlations in 172 cases of rapid eye movement sleep behavior disorder with or without a coexisting neurologic disorder

(2013) B.F. Boeve et al.   SLEEP MEDICINE

TDP-43 skeins show properties of amyloid in a subset of ALS cases

(2012) John L. Robinson et al.   ACTA NEUROPATHOLOGICA

A harmonized classification system for FTLD-TDP pathology

(2011) Ian R. A. Mackenzie et al.   ACTA NEUROPATHOLOGICA

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Hippocampal sclerosis in advanced age: clinical and pathological features

(2011) Peter T. Nelson et al.   BRAIN

Estimating the Number of Persons with Frontotemporal Lobar Degeneration in the US Population

(2011) David S. Knopman et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

(2011) Heiko Braak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Classification of primary progressive aphasia and its variants

(2011) M. L. Gorno-Tempini et al.   NEUROLOGY

Neuropathologic Correlates of Hippocampal Atrophy in the Elderly: A Clinical, Pathologic, Postmortem MRI Study

(2011) Robert J. Dawe et al.   PLoS One

Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies

(2009) Manuela Neumann et al.   ACTA NEUROPATHOLOGICA

Transactivation Response DNA-Binding Protein 43 Microvasculopathy in Frontotemporal Degeneration and Familial Lewy Body Disease

(2009) Wen-Lang Lin et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Brains With Medial Temporal Lobe Neurofibrillary Tangles But No Neuritic Amyloid Plaques Are a Diagnostic Dilemma But May Have Pathogenetic Aspects Distinct From Alzheimer Disease

(2009) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Modeling the Association between 43 Different Clinical and Pathological Variables and the Severity of Cognitive Impairment in a Large Autopsy Cohort of Elderly Persons

(2008) Peter T. Nelson et al.   BRAIN PATHOLOGY

TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis

(2008) Vivianna M Van Deerlin et al.   LANCET NEUROLOGY

Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype

(2008) K. A. Josephs et al.   NEUROLOGY

TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

(2008) J. Sreedharan et al.   SCIENCE