Resistance and resilience to Alzheimer’s disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Resistance and resilience to Alzheimer’s disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort
Authors
Keywords
Resistance, Resilience, Alzheimer’s disease neuropathologic change, TDP-43, Hyperphosphorylated tau, Dementia, <em class="EmphasisTypeItalic ">C. elegans</em>
Journal
Acta Neuropathologica Communications
Volume 7, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-06-07
DOI
10.1186/s40478-019-0743-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Physical activity, common brain pathologies, and cognition in community-dwelling older adults
- (2019) Aron S. Buchman et al. NEUROLOGY
- Education and cognitive reserve in old age
- (2019) Robert S. Wilson et al. NEUROLOGY
- Tau and TDP-43 proteinopathies: kindred pathologic cascades and genetic pleiotropy
- (2019) Yevgen Chornenkyy et al. LABORATORY INVESTIGATION
- Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report
- (2019) Peter T Nelson et al. BRAIN
- Non-Alzheimer’s contributions to dementia and cognitive resilience in The 90+ Study
- (2018) John L. Robinson et al. ACTA NEUROPATHOLOGICA
- The Correlations between Postmortem Brain Pathologies and Cognitive Dysfunction in Aging and Alzheimer's Disease
- (2018) Wen-Ying Qiu et al. Current Alzheimer Research
- Assessing the Limitations and Biases in the Current Understanding of Chronic Traumatic Encephalopathy
- (2018) Nicole Schwab et al. JOURNAL OF ALZHEIMERS DISEASE
- Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration
- (2018) Laura M. Taylor et al. Molecular Neurodegeneration
- Lifestyle activities in mid-life contribute to cognitive reserve in late-life, independent of education, occupation, and late-life activities
- (2018) Dennis Chan et al. NEUROBIOLOGY OF AGING
- Resistance vs resilience to Alzheimer disease
- (2018) Eider M. Arenaza-Urquijo et al. NEUROLOGY
- The cerebellum and cognition
- (2018) Jeremy D. Schmahmann NEUROSCIENCE LETTERS
- TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer’s disease
- (2018) Sukriti Nag et al. Acta Neuropathologica Communications
- “End-Stage” Neurofibrillary Tangle Pathology in Preclinical Alzheimer's Disease: Fact or Fiction?
- (2018) Erin L. Abner et al. JOURNAL OF ALZHEIMERS DISEASE
- Neuropathologic Correlates of Cognition in a Population-Based Sample
- (2018) Brenna Cholerton et al. JOURNAL OF ALZHEIMERS DISEASE
- Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study
- (2018) Hyun-Sik Yang et al. LANCET NEUROLOGY
- The impact of education on cortical thickness in amyloid-negative subcortical vascular dementia: cognitive reserve hypothesis
- (2018) Na-Yeon Jung et al. Alzheimers Research & Therapy
- TDP-43 Neuropathologic Associations in the Nun Study and the Honolulu-Asia Aging Study
- (2018) Margaret E. Flanagan et al. JOURNAL OF ALZHEIMERS DISEASE
- Association of Apolipoprotein E ε4 With Transactive Response DNA-Binding Protein 43
- (2018) Alexandra M. Wennberg et al. JAMA Neurology
- Resistance to Alzheimer Disease Neuropathologic Changes and Apparent Cognitive Resilience in the Nun and Honolulu-Asia Aging Studies
- (2017) Caitlin S. Latimer et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer's disease: a longitudinal retrospective study
- (2017) Keith A Josephs et al. LANCET NEUROLOGY
- Safe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR
- (2017) Antonella Borgatti et al. MOLECULAR CANCER THERAPEUTICS
- Neuropathology in the Adult Changes in Thought Study: A Review
- (2017) Joshua A. Sonnen et al. JOURNAL OF ALZHEIMERS DISEASE
- Updated TDP-43 in Alzheimer’s disease staging scheme
- (2016) Keith A. Josephs et al. ACTA NEUROPATHOLOGICA
- Microinfarcts are common and strongly related to dementia in the oldest-old: The 90+ study
- (2016) María M. Corrada et al. Alzheimers & Dementia
- Clinical-pathologic correlations in vascular cognitive impairment and dementia
- (2016) Margaret Flanagan et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- TDP-43 stage, mixed pathologies, and clinical Alzheimer’s-type dementia
- (2016) Bryan D. James et al. BRAIN
- Quantitative comparison and reproducibility of pathologist scoring and digital image analysis of estrogen receptor β2 immunohistochemistry in prostate cancer
- (2016) Anthony E. Rizzardi et al. Diagnostic Pathology
- The Complex Role of Apolipoprotein E in Alzheimer’s Disease: an Overview and Update
- (2016) Laura Mahoney-Sanchez et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum
- (2016) Alberto Serrano-Pozo et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- “New Old Pathologies”: AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS)
- (2016) Peter T. Nelson et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Lifecourse Activity Participation From Early, Mid, and Later Adulthood as Determinants of Cognitive Aging: The Lothian Birth Cohort 1921
- (2016) Alan J. Gow et al. JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
- Brain pathologies in extreme old age
- (2016) Janna H. Neltner et al. NEUROBIOLOGY OF AGING
- Neuropathologic comorbidity and cognitive impairment in the Nun and Honolulu-Asia Aging Studies
- (2016) Lon R. White et al. NEUROLOGY
- Hippocampal sclerosis and TDP-43 pathology in aging and Alzheimer disease
- (2015) Sukriti Nag et al. ANNALS OF NEUROLOGY
- The TMEM106B locus and TDP-43 pathology in older persons without FTLD
- (2015) L. Yu et al. NEUROLOGY
- Multiple pathologies are common and related to dementia in the oldest-old
- (2015) Claudia H. Kawas et al. NEUROLOGY
- APOε2 and education in cognitively normal older subjects with high levels of AD pathology at autopsy: findings from the Nun Study
- (2015) Diego Iacono et al. Oncotarget
- Incidence and extent of TDP-43 accumulation in aging human brain
- (2015) Akiko Uchino et al. Acta Neuropathologica Communications
- Primary age-related tauopathy (PART): a common pathology associated with human aging
- (2014) John F. Crary et al. ACTA NEUROPATHOLOGICA
- Hippocampal sclerosis in Lewy body disease is a TDP-43 proteinopathy similar to FTLD-TDP Type A
- (2014) Naoya Aoki et al. ACTA NEUROPATHOLOGICA
- TDP-43 is a key player in the clinical features associated with Alzheimer’s disease
- (2014) Keith A. Josephs et al. ACTA NEUROPATHOLOGICA
- Perforant path synaptic loss correlates with cognitive impairment and Alzheimer's disease in the oldest-old
- (2014) John L. Robinson et al. BRAIN
- Staging TDP-43 pathology in Alzheimer’s disease
- (2013) Keith A. Josephs et al. ACTA NEUROPATHOLOGICA
- Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing
- (2013) Janna H. Neltner et al. BRAIN
- Adult Changes in Thought Study: Dementia is an Individually Varying Convergent Syndrome with Prevalent Clinically Silent Diseases that may be Modified by Some Commonly Used Therapeutics
- (2013) Thomas J. Montine et al. Current Alzheimer Research
- Resilient Brain Aging: Characterization of Discordance between Alzheimer’s Disease Pathology and Cognition
- (2013) Selam Negash et al. Current Alzheimer Research
- TDP-43 Pathology, Cognitive Decline, and Dementia in Old Age
- (2013) Robert S. Wilson et al. JAMA Neurology
- National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
- (2012) Bradley T. Hyman et al. Alzheimers & Dementia
- Quantitative comparison of immunohistochemical staining measured by digital image analysis versus pathologist visual scoring
- (2012) Anthony E Rizzardi et al. Diagnostic Pathology
- Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
- (2012) Peter T. Nelson et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach
- (2011) Thomas J. Montine et al. ACTA NEUROPATHOLOGICA
- Ecology of the Aging Human Brain
- (2011) Joshua A. Sonnen ARCHIVES OF NEUROLOGY
- Neocortical and hippocampal amyloid-β and tau measures associate with dementia in the oldest-old
- (2011) John L. Robinson et al. BRAIN
- Alzheimer Disease Pathology in Subjects Without Dementia in 2 Studies of Aging: The Nun Study and the Adult Changes in Thought Study
- (2011) Karen S. SantaCruz et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study
- (2011) Melissa E Murray et al. LANCET NEUROLOGY
- Cerebral amyloid angiopathy pathology and cognitive domains in older persons
- (2010) Zoe Arvanitakis et al. ANNALS OF NEUROLOGY
- Phosphorylation Promotes Neurotoxicity in a Caenorhabditis elegans Model of TDP-43 Proteinopathy
- (2010) N. F. Liachko et al. JOURNAL OF NEUROSCIENCE
- Neuropathological Associates of Multiple Cognitive Functions in Two Community-Based Cohorts of Older Adults
- (2010) N. Maritza Dowling et al. JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
- Propositional Density and Cognitive Function in Later Life: Findings From the Precursors Study
- (2010) Michal Engelman et al. JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
- Image Analysis Algorithms for Immunohistochemical Assessment of Cell Death Events and Fibrosis in Tissue Sections
- (2009) Maryla Krajewska et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria
- (2009) Dennis W Dickson et al. LANCET NEUROLOGY
- Human cerebral neuropathology of Type 2 diabetes mellitus
- (2008) Peter T. Nelson et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Modeling the Association between 43 Different Clinical and Pathological Variables and the Severity of Cognitive Impairment in a Large Autopsy Cohort of Elderly Persons
- (2008) Peter T. Nelson et al. BRAIN PATHOLOGY
- Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship
- (2008) Peter T. Nelson et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype
- (2008) K. A. Josephs et al. NEUROLOGY
- AD brain pathology: Vascular origins?
- (2007) Lenore J. Launer et al. NEUROBIOLOGY OF AGING
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More