Chondroitin sulfate microspheres anchored with drug-loaded liposomes play a dual antioxidant role in the treatment of osteoarthritis

Liquiritin Alleviates Depression-Like Behavior in CUMS Mice by Inhibiting Oxidative Stress and NLRP3 Inflammasome in Hippocampus

(2022) Chang Liu et al.   Evidence-based Complementary and Alternative Medicine

Overcoming barriers by local drug delivery with liposomes

(2021) S.G. Antimisiaris et al.   ADVANCED DRUG DELIVERY REVIEWS

Does glucosamine, chondroitin sulfate, and methylsulfonylmethane supplementation improve the outcome of temporomandibular joint osteoarthritis management with arthrocentesis plus intraarticular hyaluronic acid injection. A randomized clinical trial

(2021) Songül Cömert Kılıç   JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY

Modulation of Local Overactive Inflammation via Injectable Hydrogel Microspheres

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Design of liposomes as drug delivery system for therapeutic applications

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Study of chondroitin sulfate E oligosaccharide as a promising complement C5 inhibitor for osteoarthritis alleviation

(2021) Chen Yu et al.   Materials Science & Engineering C-Materials for Biological Applications

Biomimetic injectable hydrogel microspheres with enhanced lubrication and controllable drug release for the treatment of osteoarthritis

(2021) Ying Han et al.   Bioactive Materials

The Role of Inflammation in the Pathogenesis of Osteoarthritis

(2020) Yoke Yue Chow et al.   MEDIATORS OF INFLAMMATION

Liquiritin inhibits proliferation and induces apoptosis in HepG2 hepatocellular carcinoma cells via the ROS-mediated MAPK/AKT/NF-κB signaling pathway

(2020) Jia-Ru Wang et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Resveratrol counteracts IL‐1β‐mediated impairment of extracellular matrix deposition in 3D articular chondrocyte constructs

(2020) Sebastian Frischholz et al.   Journal of Tissue Engineering and Regenerative Medicine

LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis

(2020) Manoj Arra et al.   Nature Communications

Ball‐Bearing‐Inspired Polyampholyte‐Modified Microspheres as Bio‐Lubricants Attenuate Osteoarthritis

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GDF5-GelMA injectable microspheres laden with adipose-derived stem cells for disc degeneration repair

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The regulation of cartilage extracellular matrix homeostasis in joint cartilage degeneration and regeneration

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Proinflammatory polarization of stifle synovial macrophages in dogs with cruciate ligament rupture

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Chondroitin sulfate immobilized PCL nanofibers enhance chondrogenic differentiation of mesenchymal stem cells

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Recent advances in intra-articular drug delivery systems for osteoarthritis therapy

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Nrf2/ARE pathway attenuates oxidative and apoptotic response in human osteoarthritis chondrocytes by activating ERK1/2/ELK1-P70S6K-P90RSK signaling axis

(2018) Nazir M. Khan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox and NF-κB signaling in osteoarthritis

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Neuroprotective effect of liquiritin as an antioxidant via an increase in glucose-6-phosphate dehydrogenase expression on B65 neuroblastoma cells

(2017) Yoshihiko Nakatani et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis

(2017) Bruno R da Costa et al.   LANCET

Myricitrin Modulates NADPH Oxidase-Dependent ROS Production to Inhibit Endotoxin-Mediated Inflammation by Blocking the JAK/STAT1 and NOX2/p47phox Pathways

(2017) Shimei Qi et al.   Oxidative Medicine and Cellular Longevity

Impact of total knee replacement practice: cost effectiveness analysis of data from the Osteoarthritis Initiative

(2017) Bart S Ferket et al.   BMJ-British Medical Journal

Impact of total knee replacement practice: cost effectiveness analysis of data from the Osteoarthritis Initiative

(2017) Bart S Ferket et al.   BMJ-British Medical Journal

Drug-Free ROS Sponge Polymeric Microspheres Reduce Tissue Damage from Ischemic and Mechanical Injury

(2017) Kristin P. O’Grady et al.   ACS Biomaterials-Science & Engineering

Drug-Free ROS Sponge Polymeric Microspheres Reduce Tissue Damage from Ischemic and Mechanical Injury

(2017) Kristin P. O’Grady et al.   ACS Biomaterials Science & Engineering

Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis

(2016) Sergio Portal-Núñez et al.   BIOCHEMICAL PHARMACOLOGY

Intra-articular delivery of sinomenium encapsulated by chitosan microspheres and photo-crosslinked GelMA hydrogel ameliorates osteoarthritis by effectively regulating autophagy

(2016) Pengfei Chen et al.   BIOMATERIALS

Ageing and the pathogenesis of osteoarthritis

(2016) Richard F. Loeser et al.   Nature Reviews Rheumatology

Direct in vivo evidence of activated macrophages in human osteoarthritis

(2016) V.B. Kraus et al.   OSTEOARTHRITIS AND CARTILAGE

The Reactive Oxygen Species in Macrophage Polarization: Reflecting Its Dual Role in Progression and Treatment of Human Diseases

(2016) Hor-Yue Tan et al.   Oxidative Medicine and Cellular Longevity

Economic and Humanistic Burden of Osteoarthritis: A Systematic Review of Large Sample Studies

(2016) Feng Xie et al.   PHARMACOECONOMICS

Chondroitin Sulfate Immobilized on a Biomimetic Scaffold Modulates Inflammation While Driving Chondrogenesis

(2016) Bruna Corradetti et al.   Stem Cells Translational Medicine

Osteoarthritis

(2016) Johanne Martel-Pelletier et al.   Nature Reviews Disease Primers

Targets, models and challenges in osteoarthritis research

(2015) S. Thysen et al.   Disease Models & Mechanisms

Liposomes Modified with Superhydrophilic Polymer Linked to a Nonphospholipid Anchor Exhibit Reduced Complement Activation and Enhanced Circulation

(2015) Okhil K. Nag et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Particle-based technologies for osteoarthritis detection and therapy

(2015) Taylor E. Kavanaugh et al.   Drug Delivery and Translational Research

Fabrication of monodisperse liposomes-in-microgel hybrid microparticles in capillary-based microfluidic devices

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Injectable multifunctional microgel encapsulating outgrowth endothelial cells and growth factors for enhanced neovascularization

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The effects of Glycyrrhizae uralenis and its major bioactive components on pharmacokinetics of daphnetin in Cortex daphnes in rats

(2014) Wen Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Ursolic Acid Incorporation Does Not Prevent the Formation of a Non-lamellar Phase in pH-Sensitive and Long-Circulating Liposomes

(2014) Sávia C. A. Lopes et al.   LANGMUIR

Binding of Chondroitin 4-Sulfate to Cathepsin S Regulates Its Enzymatic Activity

(2013) Juliette Sage et al.   BIOCHEMISTRY

High resistance of the mechanical properties of the chondrocyte pericellular matrix to proteoglycan digestion by chondroitinase, aggrecanase, or hyaluronidase

(2013) Rebecca E. Wilusz et al.   Journal of the Mechanical Behavior of Biomedical Materials

Health economics in the field of osteoarthritis: An Expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)

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Functional folate receptor beta-expressing macrophages in osteoarthritis synovium and their M1/M2 expression profiles

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Interactions of nanoparticles with plasma proteins: implication on clearance and toxicity of drug delivery systems

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(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis

(2010) Mary B. Goldring et al.   Annals of the New York Academy of Sciences

Selenomethionine inhibits IL-1β inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX2) expression in primary human chondrocytes

(2010) A.W.M. Cheng et al.   OSTEOARTHRITIS AND CARTILAGE

Hydrogel nanocomposites: a review of applications as remote controlled biomaterials

(2010) Nitin S. Satarkar et al.   Soft Matter

The role of synovitis in osteoarthritis

(2010) Claire Y. J. Wenham et al.   Therapeutic Advances in Musculoskeletal Disease

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Nanocomposite polymer hydrogels

(2008) Patrick Schexnailder et al.   COLLOID AND POLYMER SCIENCE

Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis

(2007) C.M. Davies et al.   OSTEOARTHRITIS AND CARTILAGE