5-HT3 Receptor MX Helix Contributes to Receptor Function

Structures of highly flexible intracellular domain of human α7 nicotinic acetylcholine receptor

(2022) Vasyl Bondarenko et al.   Nature Communications

The MX-Helix of Muscle nAChR Subunits Regulates Receptor Assembly and Surface Trafficking

(2020) Jolene Chang Rudell et al.   Frontiers in Molecular Neuroscience

Delineating the Site of Interaction of the 5-HT3A Receptor with the Chaperone Protein RIC-3

(2019) Elham Pirayesh et al.   BIOPHYSICAL JOURNAL

A lipid site shapes the agonist response of a pentameric ligand-gated ion channel

(2019) Camille M. Hénault et al.   Nature Chemical Biology

Direct binding of phosphatidylglycerol at specific sites modulates desensitization of a ligand-gated ion channel

(2019) Ailing Tong et al.   eLife

Structural principles of distinct assemblies of the human α4β2 nicotinic receptor

(2018) Richard M. Walsh et al.   NATURE

Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT3A receptor

(2018) Sandip Basak et al.   NATURE

Conformational transitions of the serotonin 5-HT3 receptor

(2018) Lucie Polovinkin et al.   NATURE

Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer

(2018) Duncan Laverty et al.   NATURE

The MemProtMD database: a resource for membrane-embedded protein structures and their lipid interactions

(2018) Thomas D Newport et al.   NUCLEIC ACIDS RESEARCH

Pentameric quaternary structure of the intracellular domain of serotonin type 3A receptors

(2016) Akash Pandhare et al.   Scientific Reports

The M4 Transmembrane α-Helix Contributes Differently to Both the Maturation and Function of Two Prokaryotic Pentameric Ligand-gated Ion Channels

(2015) Camille M. Hénault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

X-ray structure of the mouse serotonin 5-HT3 receptor

(2014) Ghérici Hassaine et al.   NATURE

Agonists and antagonists induce different palonosetron dissociation rates in 5-HT3A and 5-HT3AB receptors

(2013) Sarah C.R. Lummis et al.   NEUROPHARMACOLOGY

Chemical Scale Studies of the Phe-Pro Conserved Motif in the Cys Loop of Cys Loop Receptors

(2010) Walrati Limapichat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-function study of the fourth transmembrane segment of the GABAρ1 receptor

(2010) Argel Estrada-Mondragón et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structural basis of function in Cys-loop receptors

(2010) Andrew J. Thompson et al.   QUARTERLY REVIEWS OF BIOPHYSICS

The M4 transmembrane segment contributes to agonist efficacy differences between α1 and α3 glycine receptors

(2009) Xuebin Chen et al.   MOLECULAR MEMBRANE BIOLOGY

An intramembrane aromatic network determines pentameric assembly of Cys-loop receptors

(2009) Svenja Haeger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Modular Design of Cys-loop Ligand-gated Ion Channels: Functional 5-HT3and GABA ρ1 Receptors Lacking the Large Cytoplasmic M3M4 Loop

(2008) Michaela Jansen et al.   JOURNAL OF GENERAL PHYSIOLOGY