Structural principles of distinct assemblies of the human α4β2 nicotinic receptor

The ( α 4) 3 ( β 2) 2 Stoichiometry of the Nicotinic Acetylcholine Receptor Predominates in the Rat Motor Cortex

(2017) Kristen E. DeDominicis et al.   MOLECULAR PHARMACOLOGY

Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites

(2017) Duncan Laverty et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for GABAA receptor potentiation by neurosteroids

(2017) Paul S Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites

(2017) Duncan Laverty et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for GABAA receptor potentiation by neurosteroids

(2017) Paul S Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A pipeline approach to single-particle processing inRELION

(2017) Rafael Fernandez-Leiro et al.   Acta Crystallographica Section D-Structural Biology

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

X-ray structure of the human α4β2 nicotinic receptor

(2016) Claudio L. Morales-Perez et al.   NATURE

Emerging Molecular Mechanisms of Signal Transduction in Pentameric Ligand-Gated Ion Channels

(2016) Ákos Nemecz et al.   NEURON

Distinctive effects of nicotinic receptor intracellular-loop mutations associated with nocturnal frontal lobe epilepsy

(2016) Maegan M. Weltzin et al.   NEUROPHARMACOLOGY

UniProt: the universal protein knowledgebase

(2016)   NUCLEIC ACIDS RESEARCH

Manipulation of Subunit Stoichiometry in Heteromeric Membrane Proteins

(2016) Claudio L. Morales-Perez et al.   STRUCTURE

Engineered α4β2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4–α4 interface

(2015) Philip K. Ahring et al.   NEUROPHARMACOLOGY

Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6

(2015) Timothy Grant et al.   eLife

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

Structure of the Yeast Mitochondrial Large Ribosomal Subunit

(2014) A. Amunts et al.   SCIENCE

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

A Fluorescence-Detection Size-Exclusion Chromatography-Based Thermostability Assay for Membrane Protein Precrystallization Screening

(2012) Motoyuki Hattori et al.   STRUCTURE

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Additional Acetylcholine (ACh) Binding Site at α4/α4 Interface of (α4β2)2α4 Nicotinic Receptor Influences Agonist Sensitivity

(2011) Simone Mazzaferro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tilt-Pair Analysis of Images from a Range of Different Specimens in Single-Particle Electron Cryomicroscopy

(2011) Richard Henderson et al.   JOURNAL OF MOLECULAR BIOLOGY

A Bayesian View on Cryo-EM Structure Determination

(2011) Sjors H.W. Scheres   JOURNAL OF MOLECULAR BIOLOGY

Unraveling the High- and Low-Sensitivity Agonist Responses of Nicotinic Acetylcholine Receptors

(2011) K. Harpsoe et al.   JOURNAL OF NEUROSCIENCE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Pentameric concatenated (α4)2(β2)3 and (α4)3(β2)2 nicotinic acetylcholine receptors: subunit arrangement determines functional expression

(2009) A-L Carbone et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nicotine Normalizes Intracellular Subunit Stoichiometry of Nicotinic Receptors Carrying Mutations Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy

(2009) C. D. Son et al.   MOLECULAR PHARMACOLOGY

Structural Determinants of Ca2+Permeability and Conduction in the Human 5-Hydroxytryptamine Type 3A Receptor

(2008) Matthew R. Livesey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Ion Selectivity Filter in the Extracellular Domain of Cys-loop Receptors Reveals Determinants for Ion Conductance

(2008) Scott B. Hansen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PROMALS3D: a tool for multiple protein sequence and structure alignments

(2008) Jimin Pei et al.   NUCLEIC ACIDS RESEARCH