Triphenylphosphonium-Conjugated Poly(ε-caprolactone)-Based Self-Assembled Nanostructures as Nanosized Drugs and Drug Delivery Carriers for Mitochondria-Targeting Synergistic Anticancer Drug Delivery

Reversal of doxorubicin resistance in breast cancer by mitochondria-targeted pH-responsive micelles

(2015) Pengcheng Yu et al.   Acta Biomaterialia

Multifunctional self-assembled polymeric nanoprobes for FRET-based ratiometric detection of mitochondrial H2O2 in living cells

(2015) Jing Qiao et al.   CHEMICAL COMMUNICATIONS

Surface engineering of nanoparticles for therapeutic applications

(2014) Kenya Kobayashi et al.   POLYMER JOURNAL

Targeted Delivery of Doxorubicin to Mitochondria

(2013) Graham R. Chamberlain et al.   ACS Chemical Biology

Alkyne-Azide “Click” Chemistry in Designing Nanocarriers for Applications in Biology

(2013) Pramod Avti et al.   MOLECULES

Mitochondrial Delivery of Doxorubicin by Triphenylphosphonium-Functionalized Hyperbranched Nanocarriers Results in Rapid and Severe Cytotoxicity

(2013) Theodossis A. Theodossiou et al.   PHARMACEUTICAL RESEARCH

Re-Directing an Alkylating Agent to Mitochondria Alters Drug Target and Cell Death Mechanism

(2013) Rida Mourtada et al.   PLoS One

Intracellular delivery of redox cycler-doxorubicin to the mitochondria of cancer cell by folate receptor targeted mitocancerotropic liposomes

(2012) Sarandeep Singh Malhi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Mitochondrial accumulation of a lipophilic cation conjugated to an ionisable group depends on membrane potential, pH gradient and pK a: implications for the design of mitochondrial probes and therapies

(2012) Peter G. Finichiu et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo

(2012) Swati Biswas et al.   JOURNAL OF CONTROLLED RELEASE

In Vitro assessment of the utility of stearyl triphenyl phosphonium modified liposomes in overcoming the resistance of ovarian carcinoma Ovcar-3 cells to paclitaxel

(2012) Melani A. Solomon et al.   MITOCHONDRION

Odyssey of a cancer nanoparticle: From injection site to site of action

(2012) Joseph W. Nichols et al.   Nano Today

Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics

(2012) S. Marrache et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial pharmacology

(2012) Robin A.J. Smith et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mitochondria-Targeted Small Molecule Therapeutics and Probes

(2011) Robin A.J. Smith et al.   ANTIOXIDANTS & REDOX SIGNALING

Reconstitutable charged polymeric (PLGA)2-b-PEI micelles for gene therapeutics delivery

(2011) Deepa Mishra et al.   BIOMATERIALS

Trafficking microenvironmental pHs of polycationic gene vectors in drug-sensitive and multidrug-resistant MCF7 breast cancer cells

(2010) Han Chang Kang et al.   BIOMATERIALS

Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity

(2010) Melissa Millard et al.   PLoS One

Shape-Dependent Cytotoxicity and Proinflammatory Response of Poly(3,4-ethylenedioxythiophene) Nanomaterials

(2010) Wan-Kyu Oh et al.   Small

A cytosolic phospholipase A2-like protein in the filamentous fungusAspergillus oryzaelocalizes to the intramembrane space of the mitochondria

(2009) Kohei Takaya et al.   FEMS MICROBIOLOGY LETTERS

Subcellular targeting strategies for drug design and delivery

(2009) Lawrence Rajendran et al.   NATURE REVIEWS DRUG DISCOVERY

Mitochondrial drug delivery systems for macromolecule and their therapeutic application to mitochondrial diseases☆

(2008) Yuma Yamada et al.   ADVANCED DRUG DELIVERY REVIEWS

Size-Dependent Endocytosis of Nanoparticles

(2008) Sulin Zhang et al.   ADVANCED MATERIALS

Computational Investigation of Interaction between Nanoparticles and Membranes: Hydrophobic/Hydrophilic Effect

(2008) Yang Li et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Shape Induced Inhibition of Phagocytosis of Polymer Particles

(2008) Julie A. Champion et al.   PHARMACEUTICAL RESEARCH