Mitochondrial Delivery of Doxorubicin by Triphenylphosphonium-Functionalized Hyperbranched Nanocarriers Results in Rapid and Severe Cytotoxicity

Multistage pH-Responsive Liposomes for Mitochondrial-Targeted Anticancer Drug Delivery

(2012) Ran Mo et al.   ADVANCED MATERIALS

Increased expression of bHLH transcription factor E2A (TCF3) in prostate cancer promotes proliferation and confers resistance to doxorubicin induced apoptosis

(2012) Divya Patel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Surface conjugation of triphenylphosphonium to target poly(amidoamine) dendrimers to mitochondria

(2012) Swati Biswas et al.   BIOMATERIALS

Intracellular delivery of redox cycler-doxorubicin to the mitochondria of cancer cell by folate receptor targeted mitocancerotropic liposomes

(2012) Sarandeep Singh Malhi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Tamoxifen Subcellular Localization; Observation of Cell-Specific Cytotoxicity Enhancement by Inhibition of Mitochondrial ETC Complexes I and III

(2012) Theodossis Athanassios Theodossiou et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics

(2012) S. Marrache et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and Evaluation of Multifunctional Nanocarriers for Selective Delivery of Coenzyme Q10 to Mitochondria

(2011) Anjali Sharma et al.   BIOMACROMOLECULES

Mitochondrial targeting liposomes incorporating daunorubicin and quinacrine for treatment of relapsed breast cancer arising from cancer stem cells

(2011) Liang Zhang et al.   BIOMATERIALS

Protective Role of Transient Pore Openings in Calcium Handling by Cardiac Mitochondria

(2011) Paavo Korge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Surface modification of liposomes with rhodamine-123-conjugated polymer results in enhanced mitochondrial targeting

(2011) Swati Biswas et al.   JOURNAL OF DRUG TARGETING

A novel mitotropic oligolysine nanocarrier: Targeted delivery of covalently bound D-Luciferin to cell mitochondria

(2011) Theodossis A. Theodossiou et al.   MITOCHONDRION

Dimeric Cationic Amphiphilic Polyproline Helices for Mitochondrial Targeting

(2011) Iris M. Geisler et al.   PHARMACEUTICAL RESEARCH

Mitochondrial Delivery of Biologically Active Molecules

(2011) Volkmar Weissig   PHARMACEUTICAL RESEARCH

From Serendipity to Mitochondria-Targeted Nanocarriers

(2011) Volkmar Weissig   PHARMACEUTICAL RESEARCH

Development of Novel Peptides for Mitochondrial Drug Delivery: Amino Acids Featuring Delocalized Lipophilic Cations

(2011) Shana O. Kelley et al.   PHARMACEUTICAL RESEARCH

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro

(2009) Partha Mukhopadhyay et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

TSPO Targeted Dendrimer Imaging Agent: Synthesis, Characterization, and Cellular Internalization

(2009) Lynn E. Samuelson et al.   BIOCONJUGATE CHEMISTRY

Mitochondria-targeting properties and photodynamic activities of porphyrin derivatives bearing cationic pendant

(2009) Wanhua Lei et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Mitochondrial drug delivery systems for macromolecule and their therapeutic application to mitochondrial diseases☆

(2008) Yuma Yamada et al.   ADVANCED DRUG DELIVERY REVIEWS

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Mitochondria Targeting by Guanidine− and Biguanidine−Porphyrin Photosensitizers

(2008) Martha Sibrian-Vazquez et al.   BIOCONJUGATE CHEMISTRY

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Living with death: the evolution of the mitochondrial pathway of apoptosis in animals

(2008) A Oberst et al.   CELL DEATH AND DIFFERENTIATION

Mitochondria-Penetrating Peptides

(2008) Kristin L. Horton et al.   CHEMISTRY & BIOLOGY

Core-shell type multiarm star poly(ε-caprolactone) with high molecular weight hyperbranched polyethylenimine as core: Synthesis, characterization and encapsulation properties

(2008) Xulong Cao et al.   EUROPEAN POLYMER JOURNAL

Molecular modeling and experimental evidence for hypericin as a substrate for mitochondrial complex III; mitochondrial photodamage as demonstrated using specific inhibitors

(2008) Theodossis Athanassios Theodossiou et al.   FREE RADICAL BIOLOGY AND MEDICINE

Novel Amiodarone−Doxorubicin Cocktail Liposomes Enhance Doxorubicin Retention and Cytotoxicity in DU145 Human Prostate Carcinoma Cells

(2008) Theodossis A. Theodossiou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel HPMA Copolymer-Bound Constructs for Combined Tumor and Mitochondrial Targeting

(2008) Vaikunth Cuchelkar et al.   MOLECULAR PHARMACEUTICS

Organelle-Targeted Nanocarriers: Specific Delivery of Liposomal Ceramide to Mitochondria Enhances Its Cytotoxicity in Vitro and in Vivo

(2008) Sarathi V. Boddapati et al.   NANO LETTERS

Mitochondrial Medicine: Pharmacological targeting of mitochondria in disease

(2007) J S Armstrong   BRITISH JOURNAL OF PHARMACOLOGY