Confinement and diffusion modulate bistability and stochastic switching in a reaction network with positive feedback

Positive feedback can lead to dynamic nanometer-scale clustering on cell membranes

(2014) Martijn Wehrens et al.   JOURNAL OF CHEMICAL PHYSICS

Stochastic analysis of biochemical reaction networks with absolute concentration robustness

(2014) D. F. Anderson et al.   Journal of the Royal Society Interface

Cellular Compartments Cause Multistability and Allow Cells to Process More Information

(2013) Heather A. Harrington et al.   BIOPHYSICAL JOURNAL

Stochastic transitions in a bistable reaction system on the membrane

(2013) M. Kochanczyk et al.   Journal of the Royal Society Interface

Cooperativity in Cellular Biochemical Processes: Noise-Enhanced Sensitivity, Fluctuating Enzyme, Bistability with Nonlinear Feedback, and Other Mechanisms for Sigmoidal Responses

(2012) Hong Qian   Annual Review of Biophysics

Optimal design of stimulus experiments for robust discrimination of biochemical reaction networks

(2012) R. J. Flassig et al.   BIOINFORMATICS

The Membrane Environment Can Promote or Suppress Bistability in Cell Signaling Networks

(2012) Steven M. Abel et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Identifying Dynamical Bottlenecks of Stochastic Transitions in Biochemical Networks

(2012) Christopher C. Govern et al.   PHYSICAL REVIEW LETTERS

Asymmetric Stochastic Switching Driven by Intrinsic Molecular Noise

(2012) David Frigola et al.   PLoS One

Micro/nanofabricated environments for synthetic biology

(2011) C Patrick Collier et al.   CURRENT OPINION IN BIOTECHNOLOGY

B Cell Activation Triggered by the Formation of the Small Receptor Cluster: A Computational Study

(2011) Beata Hat et al.   PLoS Computational Biology

A Density-Dependent Switch Drives Stochastic Clustering and Polarization of Signaling Molecules

(2011) Alexandra Jilkine et al.   PLoS Computational Biology

Functional Motifs in Biochemical Reaction Networks

(2010) John J. Tyson et al.   Annual Review of Physical Chemistry

Geometry-controlled kinetics

(2010) O. Bénichou et al.   Nature Chemistry

Signalling ballet in space and time

(2010) Boris N. Kholodenko et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Spatio-temporal correlations can drastically change the response of a MAPK pathway

(2010) K. Takahashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The smallest chemical reaction system with bistability

(2009) Thomas Wilhelm   BMC Systems Biology

Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells

(2009) Jayajit Das et al.   CELL

Stem Cell States, Fates, and the Rules of Attraction

(2009) Tariq Enver et al.   Cell Stem Cell

Positive feedback regulation results in spatial clustering and fast spreading of active signaling molecules on a cell membrane

(2009) Jayajit Das et al.   JOURNAL OF CHEMICAL PHYSICS

Lateral Diffusion of Membrane Proteins

(2009) Sivaramakrishnan Ramadurai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bistability by multiple phosphorylation of regulatory proteins

(2009) Orsolya Kapuy et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Stochastic dynamics and non-equilibrium thermodynamics of a bistable chemical system: the Schlogl model revisited

(2008) M. Vellela et al.   Journal of the Royal Society Interface

Feedback Loops Shape Cellular Signals in Space and Time

(2008) O. Brandman et al.   SCIENCE

Stochasticity and Cell Fate

(2008) R. Losick et al.   SCIENCE