Neurobehavioral testing in subarachnoid hemorrhage: A review of methods and current findings in rodents

Progesterone improves long-term functional and histological outcomes after permanent stroke in older rats

(2016) Bushra Wali et al.   BEHAVIOURAL BRAIN RESEARCH

Beneficial Properties of Argon After Experimental Subarachnoid Hemorrhage

(2016) Anke Höllig et al.   CRITICAL CARE MEDICINE

Deficiency of tenascin-C and attenuation of blood-brain barrier disruption following experimental subarachnoid hemorrhage in mice

(2016) Masashi Fujimoto et al.   JOURNAL OF NEUROSURGERY

Isoflurane postconditioning with cardiac support promotes recovery from early brain injury in mice after severe subarachnoid hemorrhage

(2016) Tomoko Mutoh et al.   LIFE SCIENCES

Tozasertib attenuates neuronal apoptosis via DLK/JIP3/MA2K7/JNK pathway in early brain injury after SAH in rats

(2016) Cheng Yin et al.   NEUROPHARMACOLOGY

An apoE-derived mimic peptide, COG1410, alleviates early brain injury via reducing apoptosis and neuroinflammation in a mouse model of subarachnoid hemorrhage

(2016) Yue Wu et al.   NEUROSCIENCE LETTERS

Value of Three-Dimensional Maximum Intensity Projection Display to Assist in Magnetic Resonance Imaging (MRI)-Based Grading in a Mouse Model of Subarachnoid Hemorrhage

(2016) Tomoko Mutoh et al.   MEDICAL SCIENCE MONITOR

Progesterone Treatment Shows Benefit in Female Rats in a Pediatric Model of Controlled Cortical Impact Injury

(2016) Rastafa I. Geddes et al.   PLoS One

Sex-related differences in effects of progesterone following neonatal hypoxic brain injury

(2015) Bethany L. Peterson et al.   BEHAVIOURAL BRAIN RESEARCH

Embracing failure: What the Phase III progesterone studies can teach about TBI clinical trials

(2015) Donald G. Stein   BRAIN INJURY

Topiramate attenuates early brain injury following subarachnoid haemorrhage in rats via duplex protection against inflammation and neuronal cell death

(2015) Yong Tian et al.   BRAIN RESEARCH

Recombinant osteopontin attenuates experimental cerebral vasospasm following subarachnoid hemorrhage in rats through an anti-apoptotic mechanism

(2015) Junchi He et al.   BRAIN RESEARCH

Apigenin protects blood–brain barrier and ameliorates early brain injury by inhibiting TLR4-mediated inflammatory pathway in subarachnoid hemorrhage rats

(2015) Tingting Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Effect of magnesium treatment and glucose levels on delayed cerebral ischemia in patients with subarachnoid hemorrhage: a substudy of the Magnesium in Aneurysmal Subarachnoid Haemorrhage trial (MASH-II)

(2015) Jolien F. Leijenaar et al.   International Journal of Stroke

Decreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment

(2015) Chenhui Zhou et al.   Journal of Neuroinflammation

A magnetic resonance imaging grading system for subarachnoid hemorrhage severity in a rat model

(2015) Hajime Shishido et al.   JOURNAL OF NEUROSCIENCE METHODS

Dimethylfumarate alleviates early brain injury and secondary cognitive deficits after experimental subarachnoid hemorrhage via activation of Keap1-Nrf2-ARE system

(2015) Yizhi Liu et al.   JOURNAL OF NEUROSURGERY

Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery: Design and Methods

(2015) Wai Poon et al.   JOURNAL OF NEUROTRAUMA

Sexual dimorphism in gene expression after aneurysmal subarachnoid hemorrhage

(2015) Victor Friedrich et al.   NEUROLOGICAL RESEARCH

Administration of a PTEN inhibitor BPV(pic) attenuates early brain injury via modulating AMPA receptor subunits after subarachnoid hemorrhage in rats

(2015) Yujie Chen et al.   NEUROSCIENCE LETTERS

Protective effects of Ephedra sinica extract on blood–brain barrier integrity and neurological function correlate with complement C3 reduction after subarachnoid hemorrhage in rats

(2015) Shilun Zuo et al.   NEUROSCIENCE LETTERS

Gait analysis in three different 6-hydroxydopamine rat models of Parkinson's disease

(2015) Ming Zhou et al.   NEUROSCIENCE LETTERS

Peroxisome Proliferator–Activated Receptor β/δ Alleviates Early Brain Injury After Subarachnoid Hemorrhage in Rats

(2015) Zhipeng Teng et al.   STROKE

Attention Deficits After Aneurysmal Subarachnoid Hemorrhage Measured Using the Test of Variables of Attention

(2015) S. Wallmark et al.   STROKE

Macrophage-Inducible C-Type Lectin/Spleen Tyrosine Kinase Signaling Pathway Contributes to Neuroinflammation After Subarachnoid Hemorrhage in Rats

(2015) Yue He et al.   STROKE

Soluble Epoxide Hydrolase in Hydrocephalus, Cerebral Edema, and Vascular Inflammation After Subarachnoid Hemorrhage

(2015) Dominic A. Siler et al.   STROKE

Pharmacologic Management of Subarachnoid Hemorrhage

(2015) Adam M.H. Young et al.   World Neurosurgery

Sex Differences in the Formation of Intracranial Aneurysms and Incidence and Outcome of Subarachnoid Hemorrhage: Review of Experimental and Human Studies

(2015) Nefize Turan et al.   Translational Stroke Research

Mouse cerebral magnetic resonance imaging fails to visualize brain volume changes after experimental subarachnoid hemorrhage

(2014) Etienne N. Atangana et al.   ACTA NEUROCHIRURGICA

Intelligent data analysis of instrumented gait data in stroke patients—A systematic review

(2014) Jakob Wikström et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Endovascular Perforation Subarachnoid Hemorrhage Fails to Cause Morris Water Maze Deficits in the Mouse

(2014) Eric Milner et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Simvastatin in aneurysmal subarachnoid haemorrhage (STASH): a multicentre randomised phase 3 trial

(2014) Peter J Kirkpatrick et al.   LANCET NEUROLOGY

pH-Sensitive NMDA Inhibitors Improve Outcome in a Murine Model of SAH

(2014) Haichen Wang et al.   Neurocritical Care

Effect of 18β-glycyrrhetinic acid on cerebral vasospasm caused by asymmetric dimethylarginine after experimental subarachnoid hemorrhage in rats

(2014) Dong Zhao et al.   NEUROLOGICAL RESEARCH

Ceftriaxone alleviates early brain injury after subarachnoid hemorrhage by increasing excitatory amino acid transporter 2 expression via the PI3K/Akt/NF-κB signaling pathway

(2014) D. Feng et al.   NEUROSCIENCE

Long-Term Functional Consequences and Ongoing Cerebral Inflammation after Subarachnoid Hemorrhage in the Rat

(2014) Elke Kooijman et al.   PLoS One

Neuroprotective Effect of Hydrogen-Rich Saline against Neurologic Damage and Apoptosis in Early Brain Injury following Subarachnoid Hemorrhage: Possible Role of the Akt/GSK3β Signaling Pathway

(2014) Yuan Hong et al.   PLoS One

Tert-Butylhydroquinone Alleviates Early Brain Injury and Cognitive Dysfunction after Experimental Subarachnoid Hemorrhage: Role of Keap1/Nrf2/ARE Pathway

(2014) Zhong Wang et al.   PLoS One

Metabolic Therapy with Deanna Protocol Supplementation Delays Disease Progression and Extends Survival in Amyotrophic Lateral Sclerosis (ALS) Mouse Model

(2014) Csilla Ari et al.   PLoS One

Inflammation, Vasospasm, and Brain Injury after Subarachnoid Hemorrhage

(2014) Brandon A. Miller et al.   Biomed Research International

Progesterone in experimental permanent stroke: a dose-response and therapeutic time-window study

(2013) Bushra Wali et al.   BRAIN

Delayed neurovascular inflammation after mild traumatic brain injury in rats

(2013) Yu-Duan Tsai et al.   BRAIN INJURY

Protective effect of HIF-1α against hippocampal apoptosis and cognitive dysfunction in an experimental rat model of subarachnoid hemorrhage

(2013) Yushu Dong et al.   BRAIN RESEARCH

Progesterone and vitamin D: Improvement after traumatic brain injury in middle-aged rats

(2013) Huiling Tang et al.   HORMONES AND BEHAVIOR

Delayed Progesterone Treatment Reduces Brain Infarction and Improves Functional Outcomes after Ischemic Stroke: A Time-Window Study in Middle-Aged Rats

(2013) Seema Yousuf et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Tamoxifen as an effective neuroprotectant against early brain injury and learning deficits induced by subarachnoid hemorrhage: possible involvement of inflammatory signaling

(2013) Xuebo Sun et al.   Journal of Neuroinflammation

Fifteen-year follow-up of upper limb function in children with moderate to severe traumatic brain injury

(2013) A Åhlander et al.   JOURNAL OF REHABILITATION MEDICINE

Delayed neurological deterioration after subarachnoid haemorrhage

(2013) R. Loch Macdonald   Nature Reviews Neurology

P2X7R/cryopyrin inflammasome axis inhibition reduces neuroinflammation after SAH

(2013) Sheng Chen et al.   NEUROBIOLOGY OF DISEASE

Reducing Mouse Anxiety during Handling: Effect of Experience with Handling Tunnels

(2013) Kelly Gouveia et al.   PLoS One

Chronic Hydrocephalus after Experimental Subarachnoid Hemorrhage

(2013) Peter Lackner et al.   PLoS One

Gender Influences the Initial Impact of Subarachnoid Hemorrhage: An Experimental Investigation

(2013) Victor Friedrich et al.   PLoS One

SAHIT Investigators—on the Outcome of Some Subarachnoid Hemorrhage Clinical Trials

(2013) R. Loch Macdonald et al.   Translational Stroke Research

fMRI of Working Memory Impairment after Recovery from Subarachnoid Hemorrhage

(2013) Timothy M. Ellmore et al.   Frontiers in Neurology

The neuro-behavioral profile in rats after subarachnoid hemorrhage

(2012) Matthew Boyko et al.   BRAIN RESEARCH

Inhibition of Rho kinase by hydroxyfasudil attenuates brain edema after subarachnoid hemorrhage in rats

(2012) Mutsumi Fujii et al.   NEUROCHEMISTRY INTERNATIONAL

Expression of NR2B in different brain regions and effect of NR2B antagonism on learning deficits after experimental subarachnoid hemorrhage

(2012) G. Chen et al.   NEUROSCIENCE

Randomized Trial of Clazosentan in Patients With Aneurysmal Subarachnoid Hemorrhage Undergoing Endovascular Coiling

(2012) R. Loch Macdonald et al.   STROKE

Evidence of Corticospinal Tract Injury at Midbrain in Patients With Subarachnoid Hemorrhage

(2012) Sang Seok Yeo et al.   STROKE

Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage

(2012) E. Sander Connolly et al.   STROKE

Temporal Changes in Glutamate, Glutamate Transporters, Basilar Arteries Wall Thickness, and Neuronal Variability in an Experimental Rat Model of Subarachnoid Hemorrhage

(2011) Ching-Tang Wu et al.   ANESTHESIA AND ANALGESIA

Long-term behavioral assessment of function in an experimental model for ischemic stroke

(2011) Angelo Encarnacion et al.   JOURNAL OF NEUROSCIENCE METHODS

Simvastatin Administration Ameliorates Neurobehavioral Consequences of Subarachnoid Hemorrhage in the Rat

(2011) Lucia Merlo et al.   JOURNAL OF NEUROTRAUMA

Minocycline Improves Functional Outcomes, Memory Deficits, and Histopathology after Endovascular Perforation-Induced Subarachnoid Hemorrhage in Rats

(2011) Prativa Sherchan et al.   JOURNAL OF NEUROTRAUMA

Re-Orientation of Clinical Research in Traumatic Brain Injury: Report of an International Workshop on Comparative Effectiveness Research

(2011) Andrew I.R. Maas et al.   JOURNAL OF NEUROTRAUMA

Therapeutic Benefit of Intravenous Transplantation of Mesenchymal Stem Cells After Experimental Subarachnoid Hemorrhage in Rats

(2011) Mohammad Ali Khalili et al.   Journal of Stroke & Cerebrovascular Diseases

Clazosentan, an endothelin receptor antagonist, in patients with aneurysmal subarachnoid haemorrhage undergoing surgical clipping: a randomised, double-blind, placebo-controlled phase 3 trial (CONSCIOUS-2)

(2011) R Loch Macdonald et al.   LANCET NEUROLOGY

Phosphodiesterase 5 Inhibition Attenuates Cerebral Vasospasm and Improves Functional Recovery After Experimental Subarachnoid Hemorrhage

(2011) Byung Hee Han et al.   NEUROSURGERY

Systemic L-Citrulline Prevents Cerebral Vasospasm in Haptoglobin 2-2 Transgenic Mice After Subarachnoid Hemorrhage

(2011) Gustavo Pradilla et al.   NEUROSURGERY

α7 Nicotinic Acetylcholine Receptor Agonist PNU-282987 Attenuates Early Brain Injury in a Perforation Model of Subarachnoid Hemorrhage in Rats

(2011) Kamil Duris et al.   STROKE

Vasopressin V 1a Receptors Mediate Posthemorrhagic Systemic Hypertension Thereby Determining Rebleeding Rate and Outcome After Experimental Subarachnoid Hemorrhage

(2011) Konstantin Hockel et al.   STROKE

Standardized induction of subarachnoid hemorrhage in mice by intracranial pressure monitoring

(2010) Sergej Feiler et al.   JOURNAL OF NEUROSCIENCE METHODS

Taming anxiety in laboratory mice

(2010) Jane L Hurst et al.   NATURE METHODS

Preventing Vasospasm Improves Outcome After Aneurysmal Subarachnoid Hemorrhage: Rationale and Design of CONSCIOUS-2 and CONSCIOUS-3 Trials

(2010) R. Loch Macdonald et al.   Neurocritical Care

Learning deficits after experimental subarachnoid hemorrhage in rats

(2010) H. Jeon et al.   NEUROSCIENCE

Increased brain edema in aqp4-null mice in an experimental model of subarachnoid hemorrhage

(2010) M.J. Tait et al.   NEUROSCIENCE

Mechanisms of Osteopontin-Induced Stabilization of Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in Rats

(2010) Hidenori Suzuki et al.   STROKE

Pharmacologically Augmented S -Nitrosylated Hemoglobin Improves Recovery From Murine Subarachnoid Hemorrhage

(2010) Huaxin Sheng et al.   STROKE

Atrophic Enlargement of CSF Volume after Subarachnoid Hemorrhage: Correlation with Neuropsychological Outcome

(2009) P. Bendel et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

The usefulness of operant conditioning procedures to assess long-lasting deficits following transient focal ischemia in mice

(2009) André Ferrara et al.   BEHAVIOURAL BRAIN RESEARCH

Role of gap junctions in early brain injury following subarachnoid hemorrhage

(2009) Robert Ayer et al.   BRAIN RESEARCH

Brain edema formation and neurological impairment after subarachnoid hemorrhage in rats

(2009) Serge C. Thal et al.   JOURNAL OF NEUROSURGERY

Simvastatin Treatment Duration and Cognitive Preservation in Experimental Subarachnoid Hemorrhage

(2009) Ken Takata et al.   JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice

(2009) Valentine Bouet et al.   Nature Protocols

Brain atrophy and neuropsychological outcome after treatment of ruptured anterior cerebral artery aneurysms: a voxel-based morphometric study

(2009) Paula Bendel et al.   NEURORADIOLOGY

Role of Interleukin-1β in Early Brain Injury After Subarachnoid Hemorrhage in Mice

(2009) Takumi Sozen et al.   STROKE

Role of inflammation (leukocyte-endothelial cell interactions) in vasospasm after subarachnoid hemorrhage

(2009) Kaisorn L. Chaichana et al.   World Neurosurgery

Long-term assessment of motor and cognitive behaviours in the intraluminal perforation model of subarachnoid hemorrhage in rats

(2008) Gergely Silasi et al.   BEHAVIOURAL BRAIN RESEARCH

Long-term cognitive dysfunction following experimental subarachnoid hemorrhage: New perspectives

(2008) Ken Takata et al.   EXPERIMENTAL NEUROLOGY

Combined Therapeutic Strategy Using Erythropoietin and Mesenchymal Stem Cells Potentiates Neurogenesis after Transient Focal Cerebral Ischemia in Rats

(2008) Elise Esneault et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

CatWalk gait analysis in assessment of functional recovery after sciatic nerve injury

(2008) A. Bozkurt et al.   JOURNAL OF NEUROSCIENCE METHODS

Neurological impairment in rats after subarachnoid hemorrhage—A comparison of functional tests

(2008) Serge C. Thal et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Metaanalysis of Tirilazad Mesylate in Patients with Aneurysmal Subarachnoid Hemorrhage

(2008) Yeon Gyoe Jang et al.   Neurocritical Care

Clazosentan to Overcome Neurological Ischemia and Infarction Occurring After Subarachnoid Hemorrhage (CONSCIOUS-1)

(2008) R. Loch Macdonald et al.   STROKE

A new grading system evaluating bleeding scale in filament perforation subarachnoid hemorrhage rat model

(2007) Takashi Sugawara et al.   JOURNAL OF NEUROSCIENCE METHODS