Decreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment

Multiple therapeutic effects of progranulin on experimental acute ischaemic stroke

(2015) Masato Kanazawa et al.   BRAIN

VAP-1 blockade prevents subarachnoid hemorrhage-associated cerebrovascular dilating dysfunction via repression of a neutrophil recruitment-related mechanism

(2015) Haoliang Xu et al.   BRAIN RESEARCH

Progranulin Reduced Neuronal Cell Death by Activation of Sortilin 1 Signaling Pathways After Subarachnoid Hemorrhage in Rats

(2015) Bo Li et al.   CRITICAL CARE MEDICINE

Targeting Neutrophils in Ischemic Stroke: Translational Insights from Experimental Studies

(2015) Glen C Jickling et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Metalloproteinase-9 and neutrophil gelatinase-associated lipocalin plasma and tissue levels evaluation in middle cerebral artery aneurysms

(2014) Raffaele Serra et al.   BRITISH JOURNAL OF NEUROSURGERY

Progranulin is required for proper ER stress response and inhibits ER stress-mediated apoptosis through TNFR2

(2014) Meiling Li et al.   CELLULAR SIGNALLING

Astaxanthin offers neuroprotection and reduces neuroinflammation in experimental subarachnoid hemorrhage

(2014) Xiang-Sheng Zhang et al.   JOURNAL OF SURGICAL RESEARCH

Blood–brain barrier permeability change and regulation mechanism after subarachnoid hemorrhage

(2014) Zhiqing Li et al.   METABOLIC BRAIN DISEASE

Progranulin in neurodegenerative disease

(2014) Terri L. Petkau et al.   TRENDS IN NEUROSCIENCES

Expression and cell distribution of receptor for advanced glycation end-products in the rat cortex following experimental subarachnoid hemorrhage

(2013) Hua Li et al.   BRAIN RESEARCH

Leukocyte infiltration in experimental stroke

(2013) Nina Vindegaard Grønberg et al.   Journal of Neuroinflammation

The growth factor progranulin attenuates neuronal injury induced by cerebral ischemia-reperfusion through the suppression of neutrophil recruitment

(2013) Yusuke Egashira et al.   Journal of Neuroinflammation

Progranulin Deficiency Promotes Post-Ischemic Blood-Brain Barrier Disruption

(2013) K. Jackman et al.   JOURNAL OF NEUROSCIENCE

Delayed neurological deterioration after subarachnoid haemorrhage

(2013) R. Loch Macdonald   Nature Reviews Neurology

Early Brain Injury, an Evolving Frontier in Subarachnoid Hemorrhage Research

(2013) Mutsumi Fujii et al.   Translational Stroke Research

Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits

(2012) Zong Zhuang et al.   BMC NEUROSCIENCE

Insights into the role of progranulin in immunity, infection, and inflammation

(2012) J. Jian et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Transition of research focus from vasospasm to early brain injury after subarachnoid hemorrhage

(2012) Basak Caner et al.   JOURNAL OF NEUROCHEMISTRY

Chemokine receptor CXCR2: Physiology regulator and neuroinflammation controller?

(2012) Mike Veenstra et al.   JOURNAL OF NEUROIMMUNOLOGY

Role of autophagy in early brain injury after subarachnoid hemorrhage in rats

(2012) Hongbo Zhao et al.   MOLECULAR BIOLOGY REPORTS

Exacerbated inflammatory responses related to activated microglia after traumatic brain injury in progranulin-deficient mice

(2012) Y. Tanaka et al.   NEUROSCIENCE

Neuroprotective effects of progranulin in ischemic mice

(2011) Jiang Tao et al.   BRAIN RESEARCH

Contribution of Matrix Metalloproteinase-9 to Cerebral Edema and Functional Outcome following Experimental Subarachnoid Hemorrhage

(2011) Sergej Feiler et al.   CEREBROVASCULAR DISEASES

Cellular Effects of Progranulin in Health and Disease

(2011) Louis De Muynck et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Loss of function mutations in the progranulin gene are related to pro-inflammatory cytokine dysregulation in frontotemporal lobar degeneration patients

(2011) Paola Bossù et al.   Journal of Neuroinflammation

Reduction of neutrophil activity decreases early microvascular injury after subarachnoid haemorrhage

(2011) Victor Friedrich et al.   Journal of Neuroinflammation

Comparison Evans Blue injection routes: Intravenous versus intraperitoneal, for measurement of blood–brain barrier in a mice hemorrhage model

(2010) Anatol Manaenko et al.   JOURNAL OF NEUROSCIENCE METHODS

Metamorphosis of Subarachnoid Hemorrhage Research: from Delayed Vasospasm to Early Brain Injury

(2010) Fatima A. Sehba et al.   MOLECULAR NEUROBIOLOGY

Inflammation and Cerebral Vasospasm After Subarachnoid Hemorrhage

(2010) Gustavo Pradilla et al.   NEUROSURGERY CLINICS OF NORTH AMERICA

The granulin gene family: from cancer to dementia

(2009) Andrew Bateman et al.   BIOESSAYS

Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

(2009) Fangfang Yin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration

(2008) R. Ghidoni et al.   NEUROLOGY

MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke

(2008) Anna Rosell et al.   STROKE