Wnt3A Induces GSK-3β Phosphorylation and β-Catenin Accumulation Through RhoA/ROCK

The β-catenin signaling pathway induces aggressive potential in breast cancer by up-regulating the chemokine CCL5

(2015) Rika Yasuhara et al.   EXPERIMENTAL CELL RESEARCH

Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases

(2015) Eleonore Beurel et al.   PHARMACOLOGY & THERAPEUTICS

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma

(2014) Miwako Kakiuchi et al.   NATURE GENETICS

Epidermal Growth Factor Stimulates Nuclear Factor-κB Activation and Heme Oxygenase-1 Expression via c-Src, NADPH Oxidase, PI3K, and Akt in Human Colon Cancer Cells

(2014) Gi-Shih Lien et al.   PLoS One

SIRT2 overexpression in hepatocellular carcinoma mediates epithelial to mesenchymal transition by protein kinase B/glycogen synthase kinase-3β/β-catenin signaling

(2013) Juan Chen et al.   HEPATOLOGY

IκB Kinase γ/Nuclear Factor-κB-Essential Modulator (IKKγ/NEMO) Facilitates RhoA GTPase Activation, which, in Turn, Activates Rho-associated Kinase (ROCK) to Phosphorylate IKKβ in Response to Transforming Growth Factor (TGF)-β1

(2013) Hee-Jun Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small GTPase Rap1 regulates cell migration through regulation of small GTPase RhoA activity in response to transforming growth factor-β1

(2013) Mi-Young Moon et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention

(2013) J A McCubrey et al.   LEUKEMIA

ROCK has a crucial role in regulating prostate tumor growth through interaction with c-Myc

(2013) C Zhang et al.   ONCOGENE

Synergistic Inhibition of Survival, Proliferation, and Migration of U87 Cells with a Combination of LY341495 and Iressa

(2013) Zarina Yelskaya et al.   PLoS One

Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells

(2013) Oksana Voloshanenko et al.   Nature Communications

PI3K/Akt-dependent phosphorylation of GSK3β and activation of RhoA regulate Wnt5a-induced gastric cancer cell migration

(2012) Jiaojing Liu et al.   CELLULAR SIGNALLING

Small GTPases Rap1 and RhoA regulate superoxide formation by Rac1 GTPases activation during the phagocytosis of IgG-opsonized zymosans in macrophages

(2012) Yi Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Dvl2-Dependent Activation of Daam1 and RhoA Regulates Wnt5a-Induced Breast Cancer Cell Migration

(2012) Yichao Zhu et al.   PLoS One

Ras-related GTPases Rap1 and RhoA Collectively Induce the Phagocytosis of Serum-opsonized Zymosan Particles in Macrophages

(2011) Jae-Gyu Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GSK-3: Functional Insights from Cell Biology and Animal Models

(2011) Oksana Kaidanovich-Beilin et al.   Frontiers in Molecular Neuroscience

Galectin-3 Mediates Nuclear β-Catenin Accumulation and Wnt Signaling in Human Colon Cancer Cells by Regulation of Glycogen Synthase Kinase-3β Activity

(2009) Shumei Song et al.   CANCER RESEARCH

Chronological expression of Wnt target genes Ccnd1, Myc, Cdkn1a, Tfrc, Plf1 and Ramp3

(2009) Sonja Röhrs et al.   CELL BIOLOGY INTERNATIONAL

Rho GTPase activity modulates Wnt3a/β-catenin signaling

(2009) Jessica Rossol-Allison et al.   CELLULAR SIGNALLING

Wnt signaling pathways meet Rho GTPases

(2009) K. Schlessinger et al.   GENES & DEVELOPMENT

Phosphatidylinositol 3-Kinase Signaling Does Not Activate the Wnt Cascade

(2009) Ser Sue Ng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GSK3: a multifaceted kinase in Wnt signaling

(2009) Dianqing Wu et al.   TRENDS IN BIOCHEMICAL SCIENCES

WGEF activates Rho in the Wnt–PCP pathway and controls convergent extension in Xenopus gastrulation

(2008) Kosuke Tanegashima et al.   EMBO JOURNAL

G o mediates WNT-JNK signaling through Dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells

(2008) R. K. Bikkavilli et al.   JOURNAL OF CELL SCIENCE

Phosphorylation by p38 MAPK as an Alternative Pathway for GSK3  Inactivation

(2008) T. M. Thornton et al.   SCIENCE