Protection from cigarette smoke-induced vascular injury by recombinant human relaxin-2 (serelaxin)

Relaxin protects cardiac muscle cells from hypoxia/reoxygenation injury: involvement of the Notch-1 pathway

(2015) Giulia Boccalini et al.   FASEB JOURNAL

The role of Nrf2 in oxidative stress-induced endothelial injuries

(2015) B. Chen et al.   JOURNAL OF ENDOCRINOLOGY

Protection of coronary endothelial cells from cigarette smoke-induced oxidative stress by a new MnII-containing polyamine-polycarboxilate scavenger of superoxide anion

(2015) Matteo Becatti et al.   VASCULAR PHARMACOLOGY

Smoking and Cardiovascular Disease

(2014) Barbara Messner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Synthetic relaxins

(2014) Mohammed Akhter Hossain et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Serelaxin: a potential new drug for the treatment of acute heart failure

(2014) Natalia Neverova et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Localization of relaxin receptors in arteries and veins, and region-specific increases in compliance and bradykinin-mediated relaxation after in vivo serelaxin treatment

(2013) Maria Jelinic et al.   FASEB JOURNAL

Acute treatment with relaxin protects the kidney against ischaemia/reperfusion injury

(2013) Massimo Collino et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The biology behind the atherothrombotic effects of cigarette smoke

(2013) Adam Csordas et al.   Nature Reviews Cardiology

Relaxin Protects Rat Lungs from Ischemia-Reperfusion Injury via Inducible NO Synthase: Role of ERK-1/2, PI3K, and Forkhead Transcription Factor FKHRL1

(2013) Konstantin Alexiou et al.   PLoS One

Altered redox status in the blood of psoriatic patients: involvement of NADPH oxidase and role of anti-TNF-α therapy

(2013) V.V. Barygina et al.   REDOX REPORT

Relaxin improves TNF-α-induced endothelial dysfunction: the role of glucocorticoid receptor and phosphatidylinositol 3-kinase signalling

(2012) Thomas Dschietzig et al.   CARDIOVASCULAR RESEARCH

SIRT1 modulates MAPK pathways in ischemic–reperfused cardiomyocytes

(2012) Matteo Becatti et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial

(2012) John R Teerlink et al.   LANCET

Molecular and Cellular Mechanisms of Cigarette Smoke-Induced Myocardial Injury: Prevention by Vitamin C

(2012) Archita Das et al.   PLoS One

Antioxidants protect against increased risk of atherosclerosis induced by exposure to cigarette smoke: Histological and biochemical study

(2012) Soad Shaker Ali et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Relaxin Induces Rapid Dilation of Rodent Small Renal and Human Subcutaneous Arteries via PI3 Kinase and Nitric Oxide

(2011) Jonathan T. McGuane et al.   ENDOCRINOLOGY

Cerium Oxide Nanoparticles Inhibits Oxidative Stress and Nuclear Factor- B Activation in H9c2 Cardiomyocytes Exposed to Cigarette Smoke Extract

(2011) J. Niu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Arterial Intima-Media Thickness, Endothelial Function, and Apolipoproteins in Adolescents Frequently Exposed to Tobacco Smoke

(2010) Katariina Kallio et al.  

Estrogen, hormonal replacement therapy and cardiovascular disease

(2010) Xiao-Ping Yang et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Adverse Effects of Cigarette Smoke and Induction of Oxidative Stress in Cardiomyocytes and Vascular Endothelium

(2010) Anabel Varela Carver et al.   CURRENT PHARMACEUTICAL DESIGN

Nitric oxide-mediated blood flow regulation as affected by smoking and nicotine

(2010) Noboru Toda et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Relaxin Therapy Reverses Large Artery Remodeling and Improves Arterial Compliance in Senescent Spontaneously Hypertensive Rats

(2010) Qi Xu et al.   HYPERTENSION

Relaxin inhibits early steps in vascular inflammation

(2010) Anna Brecht et al.   REGULATORY PEPTIDES

Oxidative stress and accelerated vascular aging: implications for cigarette smoking

(2009) Anna Csiszar   Frontiers in Bioscience-Landmark

VEGFR-2 inhibition augments cigarette smoke-induced oxidative stress and inflammatory responses leading to endothelial dysfunction

(2008) Indika Edirisinghe et al.   FASEB JOURNAL