Collective migration and cell jamming in asthma, cancer and development

Cellular Contraction and Polarization Drive Collective Cellular Motion

(2016) Jacob Notbohm et al.   BIOPHYSICAL JOURNAL

Epithelial tricellular junctions act as interphase cell shape sensors to orient mitosis

(2016) Floris Bosveld et al.   NATURE

Clusters of circulating tumor cells traverse capillary-sized vessels

(2016) Sam H. Au et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contact inhibition of locomotion determines cell–cell and cell–substrate forces in tissues

(2016) Juliane Zimmermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A collective route to metastasis: Seeding by tumor cell clusters

(2016) K. J. Cheung et al.   SCIENCE

Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability

(2016) D. R. Pattabiraman et al.   SCIENCE

Motility-Driven Glass and Jamming Transitions in Biological Tissues

(2016) Dapeng Bi et al.   Physical Review X

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

A self-organized biomechanical network drives shape changes during tissue morphogenesis

(2015) Akankshi Munjal et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

A molecular mechanotransduction pathway regulates collective migration of epithelial cells

(2015) Tamal Das et al.   NATURE CELL BIOLOGY

Control of cell–cell forces and collective cell dynamics by the intercellular adhesome

(2015) Elsa Bazellières et al.   NATURE CELL BIOLOGY

Unjamming and cell shape in the asthmatic airway epithelium

(2015) Jin-Ah Park et al.   NATURE MATERIALS

A density-independent rigidity transition in biological tissues

(2015) Dapeng Bi et al.   Nature Physics

Testing the differential adhesion hypothesis across the epithelial−mesenchymal transition

(2015) Steve Pawlizak et al.   NEW JOURNAL OF PHYSICS

Active Tensile Modulus of an Epithelial Monolayer

(2015) Romaric Vincent et al.   PHYSICAL REVIEW LETTERS

Putting the Squeeze on Airway Epithelia

(2015) Jin-Ah Park et al.   PHYSIOLOGY

Emergence of homeostatic epithelial packing and stress dissipation through divisions oriented along the long cell axis

(2015) Tom P. J. Wyatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physics of active jamming during collective cellular motion in a monolayer

(2015) Simon Garcia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

(2015) M. J. Schuijs et al.   SCIENCE

Cell shapes and patterns as quantitative indicators of tissue stress in the plant epidermis

(2015) Sangwoo Kim et al.   Soft Matter

Collective cell migration: guidance principles and hierarchies

(2015) Anna Haeger et al.   TRENDS IN CELL BIOLOGY

Cell jamming: Collective invasion of mesenchymal tumor cells imposed by tissue confinement

(2014) Anna Haeger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Vertex Models of Epithelial Morphogenesis

(2014) Alexander G. Fletcher et al.   BIOPHYSICAL JOURNAL

Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis

(2014) Nicola Aceto et al.   CELL

Interplay of Cell Shape and Division Orientation Promotes Robust Morphogenesis of Developing Epithelia

(2014) Fengzhu Xiong et al.   CELL

Twist1-induced dissemination preserves epithelial identity and requires E-cadherin

(2014) Eliah R. Shamir et al.   JOURNAL OF CELL BIOLOGY

Universal Area Distributions in the Monolayers of Confluent Mammalian Cells

(2014) Gary Wilk et al.   PHYSICAL REVIEW LETTERS

Power Steering, Power Brakes, and Jamming: Evolution of Collective Cell-Cell Interactions

(2014) Jeffrey J. Fredberg   PHYSIOLOGY

Collective migration and cell jamming

(2013) Monirosadat Sadati et al.   DIFFERENTIATION

Mush rather than machine

(2013) Enhua H. Zhou et al.   NATURE MATERIALS

Propulsion and navigation within the advancing monolayer sheet

(2013) Jae Hun Kim et al.   NATURE MATERIALS

The epigenetics of epithelial-mesenchymal plasticity in cancer

(2013) Wai Leong Tam et al.   NATURE MEDICINE

Alignment of cellular motility forces with tissue flow as a mechanism for efficient wound healing

(2013) M. Basan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Slow and anomalous dynamics of an MCF-10A epithelial cell monolayer

(2013) Kenechukwu David Nnetu et al.   Soft Matter

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

(2012) George T. Eisenhoffer et al.   NATURE

The airway epithelium in asthma

(2012) Bart N Lambrecht et al.   NATURE MEDICINE

Mechanical waves during tissue expansion

(2012) Xavier Serra-Picamal et al.   Nature Physics

The impact of jamming on boundaries of collectively moving weak-interacting cells

(2012) Kenechukwu David Nnetu et al.   NEW JOURNAL OF PHYSICS

Collective motion

(2012) Tamás Vicsek et al.   PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS

Physico-Genetic Determinants in the Evolution of Development

(2012) S. A. Newman   SCIENCE

Adhesion Functions in Cell Sorting by Mechanically Coupling the Cortices of Adhering Cells

(2012) J.-L. Maitre et al.   SCIENCE

What effect does asthma treatment have on airway remodeling? Current perspectives

(2011) Sheharyar R. Durrani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Collective cell guidance by cooperative intercellular forces

(2011) Dhananjay T. Tambe et al.   NATURE MATERIALS

Effect of Bronchoconstriction on Airway Remodeling in Asthma

(2011) Christopher L. Grainge et al.   NEW ENGLAND JOURNAL OF MEDICINE

Active jamming: Self-propelled soft particles at high density

(2011) Silke Henkes et al.   PHYSICAL REVIEW E

Dynamic heterogeneity comes to life

(2011) J. P. Garrahan   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glass-like dynamics of collective cell migration

(2011) T. E. Angelini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plithotaxis and emergent dynamics in collective cellular migration

(2011) Xavier Trepat et al.   TRENDS IN CELL BIOLOGY

Do Airway Epithelium Air–Liquid Cultures Represent theIn VivoAirway Epithelium Transcriptome?

(2010) Anna Dvorak et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Movement Directionality in Collective Migration of Germ Layer Progenitors

(2010) Yohanna Arboleda-Estudillo et al.   CURRENT BIOLOGY

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Physical forces during collective cell migration

(2009) Xavier Trepat et al.   Nature Physics

The Airway Epithelium is Central to the Pathogenesis of Asthma

(2008) Stephen T. Holgate   ALLERGOLOGY INTERNATIONAL