An AFM Approach Applied in a Study of α-Crystallin Membrane Association: New Insights into Lens Hardening and Presbyopia Development

Alpha-Crystallin Association with the Model of Human and Animal Eye Lens-Lipid Membranes is Modulated by Surface Hydrophobicity of Membranes

(2022) Raju Timsina et al.   CURRENT EYE RESEARCH

Alpha-Crystallin-Membrane Association Modulated by Phospholipid Acyl Chain Length and Degree of Unsaturation

(2022) Geraline Trossi-Torres et al.   Membranes

25-Hydroxycholesterol Effect on Membrane Structure and Mechanical Properties

(2021) Marco M. Domingues et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cholesterol and cholesterol bilayer domains inhibit binding of alpha-crystallin to the membranes made of the major phospholipids of eye lens fiber cell plasma membranes

(2021) Raju Timsina et al.   EXPERIMENTAL EYE RESEARCH

Mechanical properties of the high cholesterol-containing membrane: An AFM study

(2021) Nawal K. Khadka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Association of Alpha-Crystallin with Fiber Cell Plasma Membrane of the Eye Lens Accompanied by Light Scattering and Cataract Formation

(2021) Raju Timsina et al.   Membranes

Glycation-mediated inter-protein cross-linking is promoted by chaperone–client complexes of α-crystallin: Implications for lens aging and presbyopia

(2020) Sandip K. Nandi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of Alpha-Crystallin with Phospholipid Membranes

(2020) Laxman Mainali et al.   CURRENT EYE RESEARCH

Structural and Functional Peculiarities of α-Crystallin

(2020) Olga M. Selivanova et al.   Biology-Basel

Transient elevation of temperature promotes cross-linking of α-crystallin-client proteins through formation of advanced glycation endproducts: A potential role in presbyopia and cataracts

(2020) Sandip K. Nandi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interaction of alpha-crystallin with four major phospholipids of eye lens membranes

(2020) Raju Timsina et al.   EXPERIMENTAL EYE RESEARCH

Increased Association of Deamidated αA-N101D with Lens membrane of transgenic αAN101D vs. wild type αA mice: potential effects on intracellular ionic imbalance and membrane disorganization

(2020) Om Srivastava et al.   BMC Ophthalmology

Atomic Force Microscopy as a Powerful Multifunctional Tool for Probing the Behaviors of Single Proteins

(2019) Mi Li et al.   IEEE TRANSACTIONS ON NANOBIOSCIENCE

3D structure of the native α-crystallin from bovine eye lens

(2018) Sergey N. Ryazantsev et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Membrane Disruption Mechanism of a Prion Peptide (106–126) Investigated by Atomic Force Microscopy, Raman and Electron Paramagnetic Resonance Spectroscopy

(2017) Jianjun Pan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Membrane insertion of αA-crystallin is oligomer-size dependent

(2016) Harry Christianto Tjondro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Fluid—Mosaic Model of Membrane Structure: Still relevant to understanding the structure, function and dynamics of biological membranes after more than 40years

(2013) Garth L. Nicolson   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Nanomechanical Properties of Lipid Membranes are Significantly Influenced by the Presence of Ethanol

(2013) Frank W.S. Stetter et al.   BIOPHYSICAL JOURNAL

AFM Study for Morphological Characteristics and Biomechanical Properties of Human Cataract Anterior Lens Capsules

(2012) Samjin Choi et al.   SCANNING

In Vivo Measurement of Age-Related Stiffening in the Crystalline Lens by Brillouin Optical Microscopy

(2011) Giuliano Scarcelli et al.   BIOPHYSICAL JOURNAL

Lipids and the ocular lens

(2010) Douglas Borchman et al.   JOURNAL OF LIPID RESEARCH

Nanoscale mechanical probing of supported lipid bilayers with atomic force microscopy

(2010) Chinmay Das et al.   PHYSICAL REVIEW E

Human lens lipids differ markedly from those of commonly used experimental animals

(2008) Jane M. Deeley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Multi-crystallin complexes exist in the water-soluble high molecular weight protein fractions of aging normal and cataractous human lenses

(2008) K. Srivastava et al.   EXPERIMENTAL EYE RESEARCH

The stiffness of human cataract lenses is a function of both age and the type of cataract

(2008) Karl R. Heys et al.   EXPERIMENTAL EYE RESEARCH

Presbyopia. Emerging from a blur towards an understanding of the molecular basis for this most common eye condition

(2008) Roger John Truscott   EXPERIMENTAL EYE RESEARCH