Glycation-mediated inter-protein cross-linking is promoted by chaperone–client complexes of α-crystallin: Implications for lens aging and presbyopia

Succinylation Is a Gain-of-Function Modification in Human Lens αB-Crystallin

(2019) Sandip K. Nandi et al.   BIOCHEMISTRY

The absence of SIRT3 and SIRT5 promotes the acetylation of lens proteins and improves the chaperone activity of α-crystallin in mouse lenses

(2019) Sandip K. Nandi et al.   EXPERIMENTAL EYE RESEARCH

Asp 58 modulates lens αA-crystallin oligomer formation and chaperone function

(2018) Takumi Takata et al.   FEBS Journal

Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation

(2018) Eugene Serebryany et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BAG3 Is a Modular, Scaffolding Protein that physically Links Heat Shock Protein 70 (Hsp70) to the Small Heat Shock Proteins

(2017) Jennifer N. Rauch et al.   JOURNAL OF MOLECULAR BIOLOGY

Tryptophan and Non-Tryptophan Fluorescence of the Eye Lens Proteins Provides Diagnostics of Cataract at the Molecular Level

(2017) Anna Gakamsky et al.   Scientific Reports

 B-crystallin is essential for the TGF- 2-mediated epithelial to mesenchymal transition of lens epithelial cells

(2016) R. B. Nahomi et al.   BIOCHEMICAL JOURNAL

Mass spectrometric determination of early and advanced glycation in biology

(2016) Naila Rabbani et al.   GLYCOCONJUGATE JOURNAL

Sequential Application of Glass Coverslips to Assess the Compressive Stiffness of the Mouse Lens: Strain and Morphometric Analyses

(2016) Catherine Cheng et al.   Jove-Journal of Visualized Experiments

Comprehensive Analysis of Maillard Protein Modifications in Human Lenses: Effect of Age and Cataract

(2015) Mareen Smuda et al.   BIOCHEMISTRY

Acetylation of Gly1 and Lys2 Promotes Aggregation of Human γD-Crystallin

(2014) Michael A. DiMauro et al.   BIOCHEMISTRY

Amplitude of Accommodation in Type 1 Diabetes

(2014) Adnan et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Maillard Degradation Pathways of Vitamin C

(2013) Mareen Smuda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acetylation of Lysine 92 Improves the Chaperone and Anti-apoptotic Activities of Human αB-Crystallin

(2013) Rooban B. Nahomi et al.   BIOCHEMISTRY

Antioxidant Capacity of Lenses with Age-Related Cataract

(2012) Bojana Kisic et al.   Oxidative Medicine and Cellular Longevity

Hydroimidazolone Modification of the Conserved Arg12 in Small Heat Shock Proteins: Studies on the Structure and Chaperone Function Using Mutant Mimics

(2012) Ram H. Nagaraj et al.   PLoS One

Vitamin C Degradation Products and Pathways in the Human Lens

(2011) Ina Nemet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Racemisation and human cataract. d-Ser, d-Asp/Asn and d-Thr are higher in the lifelong proteins of cataract lenses than in age-matched normal lenses

(2010) Michelle Yu Sung Hooi et al.   AGE

Glycation research in amino acids: a place to call home

(2010) Naila Rabbani et al.   AMINO ACIDS

The pathogenic role of Maillard reaction in the aging eye

(2010) Ram H. Nagaraj et al.   AMINO ACIDS

Lens aging: Effects of crystallins

(2009) K. Krishna Sharma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glyoxalase I activity and immunoreactivity in the aging human lens

(2009) Maneesh Mailankot et al.   BIOGERONTOLOGY

Significance of α-crystallin heteropolymer with a 3:1 αA/αB ratio: chaperone-like activity, structure and hydrophobicity

(2008) P. N. B. S. Srinivas et al.   BIOCHEMICAL JOURNAL

Multi-crystallin complexes exist in the water-soluble high molecular weight protein fractions of aging normal and cataractous human lenses

(2008) K. Srivastava et al.   EXPERIMENTAL EYE RESEARCH