Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER

Open source software for quantification of cell migration, protrusions, and fluorescence intensities

(2015) David J. Barry et al.   JOURNAL OF CELL BIOLOGY

Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

(2015) Joel Z. Nordin et al.   Nanomedicine-Nanotechnology Biology and Medicine

Diversity and selectivity in mRNA translation on the endoplasmic reticulum

(2015) David W. Reid et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton

(2015) Tadamoto Isogai et al.   Scientific Reports

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

The Unfolded Protein Response Triggers Selective mRNA Release from the Endoplasmic Reticulum

(2014) David W. Reid et al.   CELL

A Growth Factor-Induced, Spatially Organizing Cytoskeletal Module Enables Rapid and Persistent Fibroblast Migration

(2014) Katrin Martin et al.   DEVELOPMENTAL CELL

Tumor exosomes induce tunneling nanotubes in lipid raft-enriched regions of human mesothelioma cells

(2014) Venugopal Thayanithy et al.   EXPERIMENTAL CELL RESEARCH

Exosome Uptake through Clathrin-mediated Endocytosis and Macropinocytosis and Mediating miR-21 Delivery

(2014) Tian Tian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BMP-regulated exosomes fromDrosophilamale reproductive glands reprogram female behavior

(2014) Laura Corrigan et al.   JOURNAL OF CELL BIOLOGY

Directed evolution of APEX2 for electron microscopy and proximity labeling

(2014) Stephanie S Lam et al.   NATURE METHODS

Quantitative and stoichiometric analysis of the microRNA content of exosomes

(2014) J. R. Chevillet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De novo translation initiation on membrane-bound ribosomes as a mechanism for localization of cytosolic protein mRNAs to the endoplasmic reticulum

(2014) Sujatha Jagannathan et al.   RNA

Exosomes: the future of biomarkers in medicine

(2013) Francesca Properzi et al.   Biomarkers in Medicine

MicroRNAs Inhibit the Translation of Target mRNAs on the Endoplasmic Reticulum in Arabidopsis

(2013) Shengben Li et al.   CELL

How filopodia pull: What we know about the mechanics and dynamics of filopodia

(2013) Thomas Bornschlögl   Cytoskeleton

The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing

(2013) Lukas Stalder et al.   EMBO JOURNAL

Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1

(2013) Katrin J. Svensson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic reticulum–endosome contact increases as endosomes traffic and mature

(2013) Jonathan R. Friedman et al.   MOLECULAR BIOLOGY OF THE CELL

Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

(2013) Jerome Gilleron et al.   NATURE BIOTECHNOLOGY

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

(2013) Gaurav Sahay et al.   NATURE BIOTECHNOLOGY

Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity

(2013) H. C. Christianson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trichomonas vaginalis Exosomes Deliver Cargo to Host Cells and Mediate Host∶Parasite Interactions

(2013) Olivia Twu et al.   PLoS Pathogens

Dynamics of exosome internalization and trafficking

(2012) Tian Tian et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Exosome target cell selection and the importance of exosomal tetraspanins: a hypothesis

(2011) Sanyukta Rana et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis

(2011) J. L. Hood et al.   CANCER RESEARCH

Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis

(2011) D. Fitzner et al.   JOURNAL OF CELL SCIENCE

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Cellular Internalization of Exosomes Occurs Through Phagocytosis

(2010) Du Feng et al.   TRAFFIC

Identification and Characterization of a Small Molecule Inhibitor of Formin-Mediated Actin Assembly

(2009) Syed A. Rizvi et al.   CHEMISTRY & BIOLOGY

Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

(2009) Isabella Parolini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cross-talk between Rac1 and Cdc42 GTPases regulates formation of filopodia required for dengue virus type-2 entry into HMEC-1 cells

(2009) H. Zamudio-Meza et al.   JOURNAL OF GENERAL VIROLOGY

HIV-1 Nef Inhibits Ruffles, Induces Filopodia, and Modulates Migration of Infected Lymphocytes

(2009) C. Nobile et al.   JOURNAL OF VIROLOGY

Caveolin-1-Dependent Infectious Entry of Human Papillomavirus Type 31 in Human Keratinocytes Proceeds to the Endosomal Pathway for pH-Dependent Uncoating

(2008) J. L. Smith et al.   JOURNAL OF VIROLOGY

Filopodia: molecular architecture and cellular functions

(2008) Pieta K. Mattila et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY